The
Halobacterium
sp. NRC-1
Genome
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tbpD
Gene ID
5163
Gene Name
tbpD
Annotation
transcription initiation factor IID
Location
pNRC100:128906←128349
Gene type
Functional gene
GC content
60.215
Hydropathicity
0.067741935483871
DNA (558 bp,
Edit
)
>tbpD|5163|128906|Rev|128349
atgagtacactcaccgacaccatccagatcgagaatgtcgtcgcctcgaccgatctcagccaggagttagccctcgagca
actcgcaactgacctccccggcgctgagtacaatcccggggattttcctggtgtcatctaccggctcgacgatccgaaat
cggcgacgctcatcttcgactctggcaaagctgtctgcaccggcgcccaatctgtcgacgacgtccacgacgccatcagt
atcgtcgtcgaagacctccgcgacctcggtatcgacatcccgcccagtccgccggttcacgtccagaatatcgtctgcag
cggcagtctggaccaagatctgaacctgaacgcgatcgccatcggactcggcctcgaagacgtcgaatacgaacccgaac
agttccccggcctcgtctatcgcctcaacgaccccgatgttgtggtgttgttgttcggcagcggcaaactcgtcatcacg
ggtgggagcaacccagacgacgcccaccacgcactcgagatcatccatgagcggctcaccgacctcggcctcctcgagta
a
pI
3.8
MW (k)
19.88101
Translation (186 aa,
Edit
)
>tbpD|5163|gene
MSTLTDTIQIENVVASTDLSQELALEQLATDLPGAEYNPGDFPGVIYRLDDPKSATLIFDSGKAVCTGAQSVDDVHDAIS
IVVEDLRDLGIDIPPSPPVHVQNIVCSGSLDQDLNLNAIAIGLGLEDVEYEPEQFPGLVYRLNDPDVVVLLFGSGKLVIT
GGSNPDDAHHALEIIHERLTDLGLLE
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tab-delimited
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Comment
TbpD coordinates the expression of over 10% of genes in the Halobacterium NRC-1 genome together with TfbA, consistent with the role of these two transcription factors in gene regulation. Some of the regulated genes code for heat shock proteins and their deletion leads to a temperature sensitive phenotype. See Coker and DasSarma [BMC Genetics 2007 Sep 24;8:61](https://www.ncbi.nlm.nih.gov/pubmed/17892563). This gene was formerly labeled as a chp 04/02 (chp BLAST analysis).