The
Halobacterium
sp. NRC-1
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phr2
Gene ID
1335
Gene Name
phr2
Annotation
photolyase/cryptochrome
Location
chromosome:995734←994268
Gene type
Functional gene
GC content
71.03
Hydropathicity
-0.594887525562372
DNA (1467 bp,
Edit
)
>phr2|1335|995734|Rev|994268
atgccggccgcccaaccccccggcatgcaactgttctggcaccgacgggacctccgcaccacggacaaccgcggcctcgc
agcggccgctccgggcgtgacagcggtcgacggcggccacgaccagggccctgtcgcggcggtgttctgcttcgacgacg
aggtgttggctcacgccgccccgccccgggtcgcgttcatgctggacgcgctggccgccctccgggagcgctaccgcgac
ctcggcagcgacctcattgtccgccacggcgaccccgctgcggtgctcccggcggtcgccaacgatctcgacgccacccg
ggtcgtctggaaccacgactactcggggctggccaccgaccgcgacgcgggcgtgcgcgacgccctcgacgcggcgggcg
tcgcacacgcccagttccacgacgccgtccaccaccggccgggcgagatccgcacgaacgcgggcgacccgtactcggtg
tacacgtacttctggcggaagtggcaggaccgcgagaagaacccgccggccccggagccagagcccgcggatctcgcggc
cgacaccgcgctcgcggacaccagcccgctgccgtccgtccaggagctcggcttcgcggagccggaggcggcggtccccg
acgccggaaccgcggcggcgcgatcgctgctcgatgccttccgcgagtccggcgacatctaccgctacgaggaccgccgc
gattacccccacgaggaacccacgtcgcggctctccccgcacctgaagttcggcacgatcgggatccgaacggtctacga
ggccgcacgcgcggcgaaatccgacgccgacaccgacgacgaacgcgagaacgtcgcggcgttcatcggccagctcgcgt
ggcgggagttctacgcacaagtcctgtatttcaaccagaacgtcgtctcggagaacttcaaagcgtacgagcaccccatc
gagtggcgcgacgaccccgcggcgctgcaggcctggaaggacggcgaaaccggctatccgatcgtggacgccggcatgcg
ccagctccgcgcggaagcgtacatgcacaaccgcgtgcggatgatcgtcgccgccttcctcacgaaagacctcctggtgg
actggcgggcgggctacgactggttccgggagaagctcgcggaccacgacaccgccaacgacaacggcggctggcagtgg
gccgcctccacgggcaccgacgcccagccgtacttccgggtgttcaacccgatgacccagggggagcgctacgaccccga
cgccgactacatcaccgagttcgtccccgaactccgggacgtgcccgcggacgcgatccacagctggcacgagctgtcgc
tgtccgagcgccgccgacacgccccggagtatccggaccccatcgtggaccacagccagcgccgcgaggacgcgatcgcg
atgttcgagcgtgcgcgcggcgacgagtga
E.C.#
4.1.99.3
pI
4.71
MW (k)
54.8459
Translation (489 aa,
Edit
)
>phr2|1335|gene
MPAAQPPGMQLFWHRRDLRTTDNRGLAAAAPGVTAVDGGHDQGPVAAVFCFDDEVLAHAAPPRVAFMLDALAALRERYRD
LGSDLIVRHGDPAAVLPAVANDLDATRVVWNHDYSGLATDRDAGVRDALDAAGVAHAQFHDAVHHRPGEIRTNAGDPYSV
YTYFWRKWQDREKNPPAPEPEPADLAADTALADTSPLPSVQELGFAEPEAAVPDAGTAAARSLLDAFRESGDIYRYEDRR
DYPHEEPTSRLSPHLKFGTIGIRTVYEAARAAKSDADTDDERENVAAFIGQLAWREFYAQVLYFNQNVVSENFKAYEHPI
EWRDDPAALQAWKDGETGYPIVDAGMRQLRAEAYMHNRVRMIVAAFLTKDLLVDWRAGYDWFREKLADHDTANDNGGWQW
AASTGTDAQPYFRVFNPMTQGERYDPDADYITEFVPELRDVPADAIHSWHELSLSERRRHAPEYPDPIVDHSQRREDAIA
MFERARGDE
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Comment
phr2 is a CPD photolyase that is required for UV damage repair in light and plays a major role in photoreactivation based on analysis of knockout strains. See McCready and Marcello [Biochem Soc Trans 2003 Jun;31(Pt3):694-8](https://www.ncbi.nlm.nih.gov/pubmed/12773185) and Baliga et al. [Genome Res 2004 Jun;14(6):1025-35](https://www.ncbi.nlm.nih.gov/pubmed/15140832). For a review, see DasSarma et al. [Photosynth Res 2001;70(1):3-17](https://www.ncbi.nlm.nih.gov/pubmed/16228359) and Kavakli et al. [Jan;93(1):93-103](https://www.ncbi.nlm.nih.gov/pubmed/28067410).
