The Halobacterium sp. NRC-1 Genome

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pcn

Gene ID2256
Gene Namepcn
Annotationproliferating-cell nuclear antigen
Locationchromosome:1679308←1678568
Gene typeFunctional gene
GC content64.64
Hydropathicity-0.0238866396761133
DNA (741 bp, Edit)>pcn|2256|1679308|Rev|1678568
atgttcaaggcgatagtaagcgccgacacgctccaggagacactcgactccgtgagcgtgctggtggacgagtgcaagat
ccacctcgacgacgacaccctctccattcgcgcagtcgaccccgccagcgtcggcatggtcgacctcgatctcgccgcca
ctgcgttcgaatcctatgaagccgacggcggcctcatcggcgtcaatctctcccggctggaggacatcgcgggcatggcc
gacgccggccagctcatccaactggaactcgacgaggaaacccgcaagctccacatccagatcgacggcctcgaatacac
gcttgcgctcatcgaccccgactcgatccgccaggaaccggacatcccggacctcgatctgcccgcgcacgtcgccatcg
aaggccgcgacatcgaccgcgcggtcaccgccgccgacatggtctccgaccacatcgcgctcggcgtcgacaccggcgac
gacctgttctacgtcaacgccgaaggcgacaccgacgacgtccacctcgaactcgcgcccgaccagctcatcgacctcga
cgccggcgacgcccacagcctgttcagcctcgactacctcaaggacatgaacaaggccatcccgacgaccgcggaggtcg
aactcgaactcggcgacgagttccccatcaagctgcacttcgacatcgccgacgcacaaggccacgtcacgtacatgttg
gccccgcgcatccagtccaactga
pI3.81
MW (k)26.82349
Translation (247 aa, Edit)>pcn|2256|gene
MFKAIVSADTLQETLDSVSVLVDECKIHLDDDTLSIRAVDPASVGMVDLDLAATAFESYEADGGLIGVNLSRLEDIAGMA
DAGQLIQLELDEETRKLHIQIDGLEYTLALIDPDSIRQEPDIPDLDLPAHVAIEGRDIDRAVTAADMVSDHIALGVDTGD
DLFYVNAEGDTDDVHLELAPDQLIDLDAGDAHSLFSLDYLKDMNKAIPTTAEVELELGDEFPIKLHFDIADAQGHVTYML
APRIQSN
pcn, on the large chromosome, codes for the Halobacterium sp. NRC-1 processivity clamp protein similar to the eukaryotic PCNA. The PCN gene is considered essential due to the inability to knock out the gene without the presence of a rescue plasmid containing the wild-type gene in trans. See Berquist et al. [BMC Genet. 2007 Jun 8;8:31](https://www.ncbi.nlm.nih.gov/pubmed/17559652).