polD2

Gene ID	2338
Gene Name	polD2
Annotation	DNA polymerase type II large chain
Location	chromosome:1750278←1746169
Gene type	Functional gene
GC content	68.49
Hydropathicity	-0.501970802919708
DNA (4110 bp, Edit)	>polD2\|2338\|1750278\|Rev\|1746169 atgcggcccaccgacgaaacctacttcgaaacgctggaaaccggcctcgacgacgccttcgaggtcgcggaagccgcccg ggaacgcggggaagacccgacgccgaacgtcgaaatcccggtcgcaaaggacatggccgaccgcgtcgagaacatcctcg ggatcgacggcgtcgccgagcgcgtccgcgatctcgacggcgagatgagccgcgaggaggccgcgctggagctcgtcgcg gacttcgtcgacggccgcgtcggcgactacgacaccgacgccggcaagatcgagggcgcggtccgcaccgcggttgcact gctcactgagggcgtggtcgcggcccccatcgagggcatcgaccgcgttgaagtcaacgacaacgacgacggcacccagt acgtcgcggtctactacgccggccccatccggtcggccggcggcaccgcgcaggcgctctcggtgctcgtcgccgactac gcgcgtgcgatgctcggcatcgacgcgttcaaaccccgcgacgacgagatcgagcgctacgccgaggaggtcgatctcta cgactccgagaccggtctccagtactccccgaaggacgccgaaaccacgttcatcaccgaacactgtccggtgatgctgg acggcgaagcaaccggcaacgaggaggtcgatgggttccgcgacctcgaacgcatcgacaccaactccccgcggggcggc atgtgtctcgtgctcgcggagggcatcgcgctgaaagcccccaagatccagcgctacacccggaacctcgacgaagtcgc gtggccgtggctccaggacctcatcgacggcaccatcggcgccgacgacgccgacgaagacaccccggacgccggcagcg acagcgacgcaaccgacgagggggacgcccccagtgcgagcaccgacgccgaggagccaccccgcgccgccccctcggac aagttcctccgcgacctcatcgcgggccggccggtgttcggccatccctccaaaaacggcgggttcaggctgcgctacgg gcgtgcgcgaaaccacgggaacgcgaccgcgggcgtccacccggcgacgatgcacttgctcgatgacttcctcgcgacgg gcacccagatcaagaccgaacgccccgggaaggccgcgggcatcgtccccgtcgactccatcgaggggccgacggtgaaa ctcgccaacggcgacgtccgccacatcaacgaccccgcggacgccctcgacgtccgcaacggcgtcgcggagatcctcga cgtcggcgaatacctcgtgaactacggggagttcgtggagaacaaccacgagctcgcgcccgcctcgtacgcccccgagt ggtggattcaggacctcgacgccgcgggcgcggacgtgcaagccctccgggactcgccgtacgtcgatctcaccgccccc accgccgatcaagccatggcgtgggcgaccgactacgacgccccgctgcacccggcgtacacgtacctctggcacgacat cgacgtcgagcagttccgcgcgctcgccgacgccgtcgccgacgcccacaccgacgccagcgacgacgacgaccgcggtg tgctcgtgctcgatcacaccaccaccgtgcgcgagacgctcgaagcgctcctggtcacccaccaccagggcgacgacacc atccgggtcgacgactggctgccgctggcgcgctcgctcggcgtcaccgaatcgctcgaccgggagtgggagacgctctc tgaggccgccgccgagtggcccaacgccgtccgcgcggtcaacgaagtcgcgccgttcagcgtccaggagcgcgccccca cacgcatcgggaaccgcatgggccgccccgagaaatccgaatcccgcgatctctcgccggccgtccacaccctgttcccc atcggcgacgccggcggcagccagcgcgacgtcgccgacgccgcgcggtacgcgccggacatgtccgacacgcccggcga aatccccgtccgggtcggcgaccgcgtctgtccgtcctgcgacgagcacacctacgaatcgcggtgccccgactgcgggg actggaccgacccccactacgagtgccgggactgcggtgccgtcgccacccccgacgagtccgggcgcgtcgaatgcccg aactgcgggcgggacctcgacaacgtcaccacacaggtcatcgacatcaacgacgaataccacggcgcgctccgcgccgt cggcgagcgcgagaacgccttcgaccaactcaaaggcgtcaagggactgttatccgcggagaaaacccccgaacccatgg cgaaaggcgtcctgcgcgcgaaacacgacgtcaccgcgttcaaggacggcactgtccgctacgacatgaccgacctcccg gtgaccgccgtcacacccgcggagctcgacgtcactgccgggcagttccgcgaactcggctacaaccaggacatccacgg cgaccccctcgaacacgacgaccaactggtcgaactccgcgtgcaggacgtggtgctctccgacggcgcggccgaccaca tgctcaagaccgcggacttcgtcgacgacctcctcacccagtattacggcctcgacgccttctacgacctcgacgaccgc gacgatctcgtcggcgaactcgtcttcggcatggcaccccacacgtcggccgccgtcgtcggccgcgttgccggcttcac ctccgcgtccgtcggctacgcccacccctacttccacgccgcgaaacgccggaactgcttccacccggagacgaacgtct ggttccgcgacgagtccggggagtggcaccacgacccgatcgagacgctcgtcgaggcgcgactcgatcccgacacggcc gacgaggacgacttcggagccctcgtgcaggccctcgacggcgacgtgttcgtgccctcggtgaccgaggacggcgagga gaccctccagcgagtcgaagccgtctccaaacaccccgccccggaccacctcctcgcggtcgagacgaaacgcggccggg aactgaccgtgacccccgaccactcgatgcgtcggtggaccggggacggcatcgaacgcgtcgacgcccgggaactgacg gcgggcgacgctctccccgcaccgacacaggttccgggcgacggcgagacggcgacgtccgagctgcgttccgagtccct ggacggcacacacccgcagcgacgcttcggtgacggcggcagcgtccggaccgacgaggtcgtgtccgtcgaaccggtcc gatccagcgtcgaccacacgtactccctgaccgtcgcggagaccaacacgctcgtcgcaaacggcctgttcaccgggcag tgcgacggcgacgaggactgcgtgatgctgctgatggacggcctgatcaacttctcgaagtcgtacctgccggacaagcg cggcggccggatggacgcgccgctggtgatgtcctcccgcatcgaccccgcggagatcgacgacgaagcccacaacatcg acatcgaccgcgagtacccccgggagttctacgaggcgacccgggagctggccgaccccgaggacgtggcggacctcatc accctcgcggagtcgacggtcggcaccgacgaagagtacaccggcttcgggcacacccacgccacctccaacatccacct ggggccgtcgctgtcggcgtacaagaccctggggtcgatgatggacaagatggacgcccaactggagttggcccgcaaac tccggtcggtcgccgaaaccgacgtcgccgaacgcgtcatcgagtaccacttcctcccggacctcatcgggaacctgcgc gcgttcagccgccaggaaacccggtgtctggactgtggggagaaataccgccgcatgccgctcagcggcgactgccggga gtgcggtgggcgcgtgaacctcacggtccacgagggttccgtaaacaagtacatggacaccgccatgcgggtcgccaccg agtacgactgccgggagtacacgaaacagcgcctcgaaatcatggaccgacgcctggaatccgtcttcgaggacgacacc aacaagcaaagcggcatctccgatttcatgtga
E.C.#	2.7.7.7
pI	4.22
MW (k)	150.29475
Translation (1370 aa, Edit)	>polD2\|2338\|gene MRPTDETYFETLETGLDDAFEVAEAARERGEDPTPNVEIPVAKDMADRVENILGIDGVAERVRDLDGEMSREEAALELVA DFVDGRVGDYDTDAGKIEGAVRTAVALLTEGVVAAPIEGIDRVEVNDNDDGTQYVAVYYAGPIRSAGGTAQALSVLVADY ARAMLGIDAFKPRDDEIERYAEEVDLYDSETGLQYSPKDAETTFITEHCPVMLDGEATGNEEVDGFRDLERIDTNSPRGG MCLVLAEGIALKAPKIQRYTRNLDEVAWPWLQDLIDGTIGADDADEDTPDAGSDSDATDEGDAPSASTDAEEPPRAAPSD KFLRDLIAGRPVFGHPSKNGGFRLRYGRARNHGNATAGVHPATMHLLDDFLATGTQIKTERPGKAAGIVPVDSIEGPTVK LANGDVRHINDPADALDVRNGVAEILDVGEYLVNYGEFVENNHELAPASYAPEWWIQDLDAAGADVQALRDSPYVDLTAP TADQAMAWATDYDAPLHPAYTYLWHDIDVEQFRALADAVADAHTDASDDDDRGVLVLDHTTTVRETLEALLVTHHQGDDT IRVDDWLPLARSLGVTESLDREWETLSEAAAEWPNAVRAVNEVAPFSVQERAPTRIGNRMGRPEKSESRDLSPAVHTLFP IGDAGGSQRDVADAARYAPDMSDTPGEIPVRVGDRVCPSCDEHTYESRCPDCGDWTDPHYECRDCGAVATPDESGRVECP NCGRDLDNVTTQVIDINDEYHGALRAVGERENAFDQLKGVKGLLSAEKTPEPMAKGVLRAKHDVTAFKDGTVRYDMTDLP VTAVTPAELDVTAGQFRELGYNQDIHGDPLEHDDQLVELRVQDVVLSDGAADHMLKTADFVDDLLTQYYGLDAFYDLDDR DDLVGELVFGMAPHTSAAVVGRVAGFTSASVGYAHPYFHAAKRRNCFHPETNVWFRDESGEWHHDPIETLVEARLDPDTA DEDDFGALVQALDGDVFVPSVTEDGEETLQRVEAVSKHPAPDHLLAVETKRGRELTVTPDHSMRRWTGDGIERVDARELT AGDALPAPTQVPGDGETATSELRSESLDGTHPQRRFGDGGSVRTDEVVSVEPVRSSVDHTYSLTVAETNTLVANGLFTGQ CDGDEDCVMLLMDGLINFSKSYLPDKRGGRMDAPLVMSSRIDPAEIDDEAHNIDIDREYPREFYEATRELADPEDVADLI TLAESTVGTDEEYTGFGHTHATSNIHLGPSLSAYKTLGSMMDKMDAQLELARKLRSVAETDVAERVIEYHFLPDLIGNLR AFSRQETRCLDCGEKYRRMPLSGDCRECGGRVNLTVHEGSVNKYMDTAMRVATEYDCREYTKQRLEIMDRRLESVFEDDT NKQSGISDFM
Set Format
Comment	polD2 encodes the large subunit of the heterodimeric euryarchaeal specific D family DNA polymerase on the large chromosome. This polymerase is thought to act at the lagging strand and the polD2 gene has been determined to be essential.See Berquist et al. [BMC Genet. 2007 Jun 8;8:31](https://www.ncbi.nlm.nih.gov/pubmed/17559652).