[R] (-) COG3413 Predicted DNA binding protein 9 genomes BUD0026 15 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG1488 rrnAC1193 rrnAC3490 HVO_0492 HVO_1117 HVO_B0159 Hbo2878 Hbo3768 Hmu2184 Hut0367 Hut0702 hla0221 NP1538A NP1564A HQ1863A

Pairwise sequence scores
Consensus score	1603	HQ1863A	Hut0702	Hbo3768	HVO_B0159	rrnAC1193	hla0221	VNG1488	HVO_0492	Hbo2878	Hut0367	NP1538A	HVO_1117	NP1564A	rrnAC3490	Hmu2184
780	HQ1863A	1651	484	468	527	472	510	556	532	522	632	592	621	557	608	632
751	Hut0702	484	1738	489	624	542	405	486	502	482	494	599	579	642	596	499
755	Hbo3768	468	489	1603	802	574	506	419	549	559	596	554	650	682	566	551
782	HVO_B0159	527	624	802	1533	660	477	470	631	599	629	564	592	635	592	567
774	rrnAC1193	472	542	574	660	1649	467	471	511	475	592	568	586	664	553	560
755	hla0221	510	405	506	477	467	2346	524	531	524	516	464	647	672	495	528
839	VNG1488	556	486	419	470	471	524	1644	872	804	508	584	598	613	513	529
968	HVO_0492	532	502	549	631	511	531	872	1636	1034	582	623	657	727	610	620
956	Hbo2878	522	482	559	599	475	524	804	1034	1622	609	607	667	682	625	603
837	Hut0367	632	494	596	629	592	516	508	582	609	1559	649	741	659	692	662
884	NP1538A	592	599	554	564	568	464	584	623	607	649	1590	765	686	692	671
992	HVO_1117	621	579	650	592	586	647	598	657	667	741	765	1600	860	757	686
1057	NP1564A	557	642	682	635	664	672	613	727	682	659	686	860	1625	772	647
894	rrnAC3490	608	596	566	592	553	495	513	610	625	692	692	757	772	1597	801
876	Hmu2184	632	499	551	567	560	528	529	620	603	662	671	686	647	801	1554

347 symbols
consensus       ------------------------------------------------------------
#oth            111111111111111111111111111111111111111111111111111111111111
HQ1863A         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
Hut0702         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
Hbo3768         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
HVO_B0159       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
rrnAC1193       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
hla0221         MSHASANSLVVIAVSAAPRIARQSGSASASNVSSSVSSPSVAVVGPVACGTFRFMDVGSG
VNG1488         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
HVO_0492        ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
Hbo2878         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
Hut0367         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP1538A         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
HVO_1117        ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP1564A         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
rrnAC3490       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
Hmu2184         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::

consensus       ----------------------------------------------MPAGIRAEVEVDGP
#oth            111111111111111111111111111111111111111111112336823333263872
HQ1863A         ::::::::::::::::::::::::::::::::::::::::::::::::D:::T:LA:HN:
Hut0702         ::::::::::::::::::::::::::::::::::::::::::::::-ME::::KLVIEE:
Hbo3768         :::::::::::::::::::::::::::::::::::::::::::::MTGQ:VH:::::VTG
HVO_B0159       ::::::::::::::::::::::::::::::::::::::::::::::----VHG:IH:AD:
rrnAC1193       :::::::::::::::::::::::::::::::::::::::::::::::SGR:L:::::F::
hla0221         SVHPNTGPAYVGCFIRNRRSVAPVCERRRRADGVNVLSDGGHERTQ:GS::::::SLPTA
VNG1488         ::::::::::::::::::::::::::::::::::::::::::::::::::::VT:SFPR:
HVO_0492        :::::::::::::::::::::::::::::::::::::::::::::::::::::T::F:S:
Hbo2878         ::::::::::::::::::::::::::::::::::::::::::::::::P::::T:AFTT:
Hut0367         ::::::::::::::::::::::::::::::::::::::::::::::----M:::I::LS:
NP1538A         ::::::::::::::::::::::::::::::::::::::::::::::--M:LE:A:KIPN:
HVO_1117        ::::::::::::::::::::::::::::::::::::::::::::MTSA::::::LK:T::
NP1564A         :::::::::::::::::::::::::::::::::::::::::::::::S:::::::R:::G
rrnAC3490       :::::::::::::::::::::::::::::::::::::::::::::MSDS:::V:LS::A:
Hmu2184         :::::::::::::::::::::::::::::::::::::::::::::::SE:L:V:LAI:S:

consensus       EACPVADVSDEADTPVTSVSRSVVGAD-GTVVEEFTA--DADAAPD------EDLEPVFD
#oth            7813258536864764632323774667274451.7423763565611123477536218
HQ1863A         TN:::STI:ATQEGS::DINWTGQ::N:E::T:::RVSQ:ISS:VE:::SDF:CA:::V:
Hut0702         PQ:D::A::RDCG-::A:::::A:PDED:R:HD:::V::REGDC::::::TLG:ATAI:Q
Hbo3768         AG:RIGNMPQKTE-EIS:I:::TMPSE:DS:TVD:::::ESGTEFN::::::-ST:E::H
HVO_B0159       SI:R:SEA:K--E:A:E:::::-:::TGD:AAV::::::PSS::I:::::::-:ADEI:H
rrnAC1193       RS:H:QPHA::-EWS:S::::::TS:AADP:I::::L:KGG:GP:SVLQTDGLNVDH::A
hla0221         SPS:FDG:V:-GS::IY::A::SSNG:PE:::L::I::::::LPVS:::::::GV:V:::
VNG1488         PV::I:VL:ER:N:TI:N::T:IAAD-::AP:T::LI::::::V::::::D:Y:RD:::T
HVO_0492        SV::::S:AHST:SV:D:::T:::STPGEVS:S::VL::E::DP::::::A:SA:::I:S
Hbo2878         DL::IVEL::A:EIT:D::ATN:PAS:C:EC:T::S:::::::DSE::::::T::T:I:S
Hut0367         ::::::GL:EQ::D:L:::::--A:NAE:::T::::V::SG::TLT::::D:DR:SQL:E
NP1538A         :Q:::::::A:::AR:GD::W:G:PN:D:S:::::EL:::T::D:P::::::D:M:K::G
HVO_1117        DG::::T::E-G::SGYAL:::MAPNER:S:::::VF:::D::EVP:::::::EM:EL:E
NP1564A         GS::::VA:AD:G::TY::A:::T:S:PDR:T:::ML::A:EGT::::::AGT:::A:::
rrnAC3490       G:::::S:::::G:A::D:A::-SPDAD:Q:I:::::TGTD:G:IE::::AR::M:K::V
Hmu2184         :::::::A:ERV:GS::N:T::TG:--:EA:::::S:::P:GTDVG:::::::AV::L:E

consensus       YGDKTVYRFSRDRGAG--CPCECVEAFGCPVADIRARDGSLVLTFHAADVETLRAIVAEL
#oth            556655213736866622141462286243164563562816333345365831422781
HQ1863A         V::ER::::K:NHEEA:::A::I::SS:A::::V:::S:V:H::L:LES:DK::T::DK:
Hut0702         DDRR:I::LA:S::Q::::A:::I:RE::T:R:VQVV::T:FV:VL:::LDGI::::ST:
Hbo3768         :D::::H::ECKT:TTPS::::F::SR::::RSF:TTENA::VQ:V:R:IRN::E::VG:
HVO_B0159       HEQ::I::VTHSFTEESR:A::LI:GH::::RHLE:DC:AV::S:V:::L:SF:D::VN:
rrnAC1193       :EQRH:FQL::AA:Q::::V::RI::A::V:HEFT:DTE:::V::LVD::P:::E:::D:
hla0221         ::A:AA:::KVP:VEA::S:FAILDRHSV::SETTI:::R::V::::T:LP:::SVLD:F
VNG1488         :T:RHL::VRH:AE:A:::::V:LG:HDT::NRY:::::E:QIV::GREFD:VQ:::G::
HVO_0492        ::S:HL::YTH:GS:D:::::::LGE:::::DRYF:QR:::T:V:::::Y:Q:Q:VIG::
Hbo2878         H:PTNR:::TH:D:VN:::::::LGQ::::::RYV:Q::H:T:V:::::Y:E::SV::::
Hut0367         :RSAS::::HHES-LD:::V::F::DHDH:ISE:::Q::::::SL:LTTIQD::DL:TD:
NP1538A         DNRYSI:::D:AGD:P:::I:QRI:T:::::::VE:V::::RIV:RP::::S:QE::GT:
HVO_1117        :::GS::::D:EG:I:::::::R::::D:::V:VQT:::A:F:::::P::::::DV::A:
NP1564A         ::S::M:::::E::V:::::::VI:VED:::V::HT:::N:H:V:::::M:::QEVIFS:
rrnAC3490       T:NG:R:Q:::S:-TE:::V::A::TYD::::::::EG:Q:R:::::P::DRV::::TR:
Hmu2184         N:SEAR:::R::PDQD:::F:DA::T:D:A:S::Q:E::QVIA:A:VD:AAQV::V:E::

consensus       RERFGDVDLRRLVRSPE--GTEEDDLVL-VDRGKLTDRQREVLETAYEMGYFEHPRGANA
#oth            3456543625424356611655776634132135..4..3...32.231...42.24.11
HQ1863A         DDAAER:E::Y::HADASG:SD:P:RA::::::A:::::Q:::Q:::S::::QY::D:::
Hut0702         ::SRDG:QVGT:::A:P::ES:SGP:WV:T:P:E::A::::::::::::::::Y::N:T:
Hbo3768         ::Q:P::S::::T::Q:::PEANNN::::IN:DT::E::Q::::::H:::::G::KD:::
HVO_B0159       KSA:DG:S::::TQ:EP::DSATGS::F::::DE::A:::::::::H:::::::::E:::
rrnAC1193       QSEGEA:K::::LEDTP::-::A:RP:V:L::A:::S::::::AR:H:::::::::D:T:
hla0221         ::SCS:MQVL::LQ:SS::TP::S:::T::::SE::E::::::TA::DA:::D::K::::
VNG1488         :AE:A:I:IQ::::A:T::::AAQ:TAF:::::Q:::::L:::T::::A::::R::::T:
HVO_0492        :D::PGL:IK::::::T:::DAPG:S:F::::::::T::L:::Q:::D:::::R::::::
Hbo2878         :D::P:::IK:F::::A::VEQSQ:S:F::::S:::T::L:::Q:::D:::::R::R:::
Hut0367         :::Y:A:RI:Y:LQVES::DE:GSTD:IPI::SR:::::K:::::::R::::SY::D:::
NP1538A         QRE::GIQ:EH::Q:S:::P::GE-T:V:::::R:::::::::::::::::::::K::::
HVO_1117        ::SS:S::V:::LQ:ST::-D:SR::::::E::Q::::::::::::H:::::D:::R::K
NP1564A         ::::PS::VQ::L:DQH::EAP::N:I::L::SR::::::::::::H::::::::M::::
rrnAC3490       K:LYDG:S::SMR:NGD::VDPV:-SI:::::S::::::Q::::::VD:::::Y:K::::
Hmu2184         :DA::::A::S:HQHG:::::LG:-A:V:::::Q::::::::::::H:::::DY:K::::

consensus       GEVAAELDINTSTFTEHLAAAQSKLLDDILDE---------------
#oth            332.43.11572.131.122.231.1355168632111111111111
HQ1863A         TT::D::G:GL::::::::V::R:::SEL:SQRV:::::::::::::
Hut0702         EA::T:::VA:P::::::::::RN::EGF::GSDNQSDTTIQSSHGQ
Hbo3768         T:::NA::::R:::A:::S::::::::S::EF:::::::::::::::
HVO_B0159       T::::A::::R:::::::S::::::::T:::V:::::::::::::::
rrnAC1193       :D::DA:::S::::::::::::R:::::L::SC::::::::::::::
hla0221         ::::ES:G:DR:::S::M::::R:::SAL::-:::::::::::::::
VNG1488         QAL:DD:G:AP:::::::L:::R:::G:A:ETDGT::::::::::::
HVO_0492        T:::::::::Q:::S::::::LT:::G:V:E:G::::::::::::::
Hbo2878         T:I:::::::P::L:::::::E::::E:::--:::::::::::::::
Hut0367         TD:::::::DG::::::::::::::M:EL:A:M::::::::::::::
NP1538A         ::::D::G::SA:LRG::S::::::::EM:A-:::::::::::::::
HVO_1117        :::::::G:T::::S::::M::K::MGA::Q::::::::::::::::
NP1564A         ::::D::::T::::S::::::::::::A:::A:::::::::::::::
rrnAC3490       :D::T::::SV:::A:::::::T::::S:VA::::::::::::::::
Hmu2184         ::::EA:::SV::LA:::::::T:::::V:P-:::::::::::::::