[P] (PhoU) COG0704 Phosphate uptake regulator 9 genomes BUD0102 10 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG0458 rrnAC1510 rrnAC2150 HVO_2374 Hbo2073 Hmu2070 Hut1609 hla1707 NP1976A HQ3308A

Pairwise sequence scores
Consensus score	2433	VNG0458	hla1707	HQ3308A	HVO_2374	Hbo2073	NP1976A	Hut1609	Hmu2070	rrnAC1510	rrnAC2150
1670	VNG0458	2485	1592	1543	1536	1562	1479	1445	1452	1456	1466
1926	hla1707	1592	2632	1797	1913	1956	1605	1534	1549	1544	1558
1860	HQ3308A	1543	1797	2432	1922	2013	1541	1548	1510	1534	1565
1940	HVO_2374	1536	1913	1922	2429	2178	1574	1539	1578	1581	1593
2011	Hbo2073	1562	1956	2013	2178	2443	1632	1599	1583	1605	1621
1843	NP1976A	1479	1605	1541	1574	1632	2445	1637	1673	1689	1662
1932	Hut1609	1445	1534	1548	1539	1599	1637	2451	1878	1909	1938
1898	Hmu2070	1452	1549	1510	1578	1583	1673	1878	2420	1927	2016
1939	rrnAC1510	1456	1544	1534	1581	1605	1689	1909	1927	2421	2174
1964	rrnAC2150	1466	1558	1565	1593	1621	1662	1938	2016	2174	2435

361 symbols
consensus       -------------------------METRKVQVTGGSTYTVSIPKEWATENDVSAGSVVE
#oth            11111111111111111111111121.1....1.....1...1..3..2212112.2111
VNG0458         :::::::::::::::::::::::::::R::::::::::F::::::D::RDHS:E::DE:G
hla1707         MGQRSGCTSVYISDNLKGDGIRYRG::::::::::::::::::::T:::::::E::TEI:
HQ3308A         ::::::::::::::::::::::::MV::::::::::::F:::::::::NS::I:::::::
HVO_2374        ::::::::::::::::::::::::MV:::::::::::::::::::D:::D:G:::::E::
Hbo2073         ::::::::::::::::::::::::MV:::::::::::::::::::D:::::S:::::E::
NP1976A         ::::::::::::::::::::::::::::::::::::::::::L::G::::::I:G:::::
Hut1609         ::::::::::::::::::::::::::::::::::::::::::L:::::::::::::::::
Hmu2070         ::::::::::::::::::::::::::::::::::::::::::L:::::::::::::::::
rrnAC1510       ::::::::::::::::::::::::::::::::L:::::::::L::::::::G:ES:::::
rrnAC2150       ::::::::::::::::::::::::::::::::::::::::::L:::::::::::::::::

consensus       FHPEGDSLLLTPRRDDERTEGTLDITGLEGD-ELTRAVMTMYVSGFDIIALEAARITAEQ
#oth            .121422.112.34242342.111133152321.1...2........115.13531224.
VNG0458         :::DSG::::::ID:TDTDK:::T::DMH:E:::M::::::::::::VL::::ES:DPD:
hla1707         :::D::::F::::SEE:::R::I:::D:S:Q:A:::::T::::::::V:E::GTE::T::
HQ3308A         :Y::::::::A:TT:E:::R:S::V:D:A:E::::::::::::::::::S:TSS:::TT:
HVO_2374        :Y::::::F::::SEE:::::::::AT:::::::::::::::::::::::::SS:::TD:
Hbo2073         :Y::::::F::::TE::::::::::AN:A:::::::::::::::::::::::SG:::T::
NP1976A         ::::EE:::::::HG:DKI:::::::::::::::M:::V::::::::::T::T:QVS:A:
Hut1609         ::S:E:M:::S:QD:R::A::S::VS::TEET:::::::::::::::::R:::P::S:T:
Hmu2070         ::A:E:L:::S:::ENG:V::::::S::DE:H:::::::::::::::V:T::TP::SPK:
rrnAC1510       :YA:D:L::VS:QHG:DHV:::::V::::NRH:::::::::::::::::R::::::::::
rrnAC2150       ::A:R:L:::A:Q::NG:V::S::VE:::NRH:::::::::::::::::Q:::T::::::

consensus       RRTIRDATQGLVGLEVIEETRDRVVLQDLLDSSELSIHNAVTRMRLISLSMLEDAVAALA
#oth            .131.2.1.1.....111..43.1121.........22..11..2.1121.13..13.14
VNG0458         ::V:::::::::::::L:::SQ:::I:::::::::::::::R::H::AV:::::::T:::
hla1707         :S:V:E:V::::::::L::::N:::V:::::::::::::::::::::::::::::I:::S
HQ3308A         :::::E:::S::::::L::::::I:VR::::::::::::::::::::A::::G::ID:I:
HVO_2374        :::::E:::S::::::L::::::::IR::::::::::::::::::::A:::::::I::I:
Hbo2073         :::::E:::S::::::L::::::::IR::::::::::::::::::::::::::::I::I:
NP1976A         :::::::::::::::::G::SG::R:::::::::::M:::::::::VATT::A:::T::L
Hut1609         ::Y::N::::::::::::::G:::::::::::::::VN::I:::::V::T:TA:::T::I
Hmu2070         ::VV:::V::::::::::::S:::::::::::::::V:::I:::Q:V::T::A:::D::V
rrnAC1510       ::I::::::::::::M::::A:::::::::::::::VL::I:::::V::T::S:::E::I
rrnAC2150       ::I::::::::::::M::::T:::::::::::::::V:::I:::::V::T::S:::E::I

consensus       EDDDDLAADVIQRDDDVDRLWYMVSRIFRTVLRNPTAAEEIGLPRETCFDYQSSARQLER
#oth            33.412.1.134..1.1....31...1..32..3.21.422.23..42..11.2......
VNG0458         TR:P:I:R::TN::::::::::V::::::GA::S::V:Q:::IT::VA:::H::::::::
hla1707         :R:H:::R:::G::::L::::LV::::::AT::T:K::::L:::::E::::H::::::::
HQ3308A         TL:T:M:R:I:::::::::::MV::::::ST::T:K::::L::E::M::::::A::::::
HVO_2374        KQ:::M:R:::::::::::::MV::::::AT::T:K::::L:::::I::::::A::::::
Hbo2073         :L:::M:R:::::::::::::MV::::::AT::T:K::::L:::::V::::::A::::::
NP1976A         D:::E:::::V::::::::::S::::V::S:::D:S::AT:::D:::::::H::::::::
Hut1609         ::::E:::::ME::::::::::::::V:::::::::::NDM:F::::V:::::G::::::
Hmu2070         :::::::::::H::E:::::::::::V:::::::::::T:::F::::V::::::::::::
rrnAC1510       :::N::::::::::::::::::::::V:::::::::::N:::F::::V::::::::::::
rrnAC2150       ::::::::::M:::::::::::::::V:::::::::::N:::F::::V::F:::::::::

consensus       IADHATKIAHLSLNIEEPIPEDVADALDELRAEAISVPETAMDALLADDSDEATRLANEA
#oth            11...2..143254243333314333253.66216512241.1..12223231241.231
VNG0458         V::::::::TATHDLNDD:::::V:::ET:Q:D:TDII:::::::F::TA::::A::TQ:
hla1707         :G:::::::::T:::D::L:D::VE:VN::HGD:VE:ID::::::F::::E:::::::::
HQ3308A         ::::::::G::T:KFN:QV::::I:S:M::CD::Q:IVDA:::::FTA:NNKV:D:::D:
HVO_2374        :G::::::::::::F:::VDGEIVQ:IQ::FKDTE::VNGG::::F:EE::::S:::::S
Hbo2073         :G:::::::::T::F:::VS:::VS::E::YM::RK:VDDG::::FT::P:::S::::D:
NP1976A         :G:::A:::THAETLST:-:T:A:::IRD:HD::TE:VDMG:::::E::::R:::::HD:
Hut1609         :::::N:::DIATD::A-V::EE::::::::EI::::::::::::::::P:::VS:::::
Hmu2070         :::::::::E::RE:DA-:SGETGEK:RT::E::AT::::::E:::::::EA:VEQ::Q:
rrnAC1510       :::::::::S::QE:G:-:TGET::L::Q:ET:::A:::::::::::::N:::VE:::::
rrnAC2150       :::::::::S::QE:G:-:TGET:EL::Q:E::::A::::::::::TE:::::VE:::G:

consensus       RERIQDIDERAREVDELLRELD-PQRAQLLGLVVDSLSRSADYGGNIAETALQKAAPTP-
#oth            .461441.262.61.34213211133.13..11...11.1....1.1..1...1.1.2.3
VNG0458         :AQVR:::DQ::D::DR:HG:T:AHH::H::::::::::::::::::::::::::::::N
hla1707         :TGVRA::::V:AI:::::D::::T:::::::::::VL::::::::V:::::::::::::
HQ3308A         ::SV:Q::::::QI:::::G::::A:::::::I:::V:::::::::::::::::::::::
HVO_2374        ::AV:A::AS::GI:::::D::::A:::::::I:::V:::::::::::::::::::::::
Hbo2073         ::NV:Q::::::KI:::::D::::A:::::::I:::V:::::::::::::::::::::::
NP1976A         :T::ANV::LT:R::DEI:::::::Q:::::::::::::::::::::::::::N:::K::
Hut1609         :G::PEV::K:::::S:I:QF:D::::HR::::::::::T::::S::::S:::::V:R:A
Hmu2070         :GT:E:V:AM::::::QV::A::::S::V::::::::::T:::::::::S:::::::R::
rrnAC1510       :S::PEV::T:::::GKV:::::::S:::::R:::::::T:::::::::S:::::::R::
rrnAC2150       :SQ:P:V::T:::::GQI::F::::S::V:::I::::::T:::::::::S:::::::R:Q

consensus       -
#oth            2
VNG0458         P
hla1707         :
HQ3308A         :
HVO_2374        :
Hbo2073         :
NP1976A         :
Hut1609         :
Hmu2070         :
rrnAC1510       :
rrnAC2150       S