[P] (PhoU) COG0704 Phosphate uptake regulator 9 genomes BUD0103 10 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG0766 pNG7066 rrnAC0819 HVO_1181 Hbo0378 Hmu1528 Hut1001 hla2608 NP1386A HQ2746A

Pairwise sequence scores
Consensus score	2514	pNG7066	Hut1001	VNG0766	NP1386A	rrnAC0819	Hmu1528	hla2608	HQ2746A	HVO_1181	Hbo0378
1084	pNG7066	2695	957	1047	946	944	892	943	981	1044	982
1997	Hut1001	957	2515	1802	1903	1905	1811	1731	1754	1841	1757
2003	VNG0766	1047	1802	2493	1862	1848	1738	1857	1842	1898	1801
2192	NP1386A	946	1903	1862	2517	2109	1944	1959	1938	2010	1938
2194	rrnAC0819	944	1905	1848	2109	2505	2093	1979	1949	2004	1885
2026	Hmu1528	892	1811	1738	1944	2093	2390	1803	1813	1888	1846
2138	hla2608	943	1731	1857	1959	1979	1803	4087	2013	2076	1997
2135	HQ2746A	981	1754	1842	1938	1949	1813	2013	2501	2074	2012
2251	HVO_1181	1044	1841	1898	2010	2004	1888	2076	2074	2506	2162
2159	Hbo0378	982	1757	1801	1938	1885	1846	1997	2012	2162	2408

543 symbols
consensus       ------------------------------------------------------------
#oth            111111111111111111111111111111111111111111111111111111111111
pNG7066         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
Hut1001         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
VNG0766         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP1386A         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
rrnAC0819       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
Hmu1528         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
hla2608         MVAVSTSPPPPTATRSLEVALHLGDQLVGVDRLRHVPVGTGLHRLHHLLLLVDARTHHDH
HQ2746A         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
HVO_1181        ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
Hbo0378         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::

consensus       ------------------------------------------------------------
#oth            111111111111111111111111111111111111111111111111111111111111
pNG7066         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
Hut1001         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
VNG0766         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP1386A         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
rrnAC0819       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
Hmu1528         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
hla2608         GVGPAVLDRSSRLDSGHLGHDDVHRHRIRFVRLEQLHRLRAVLRLADHLEGILQRVPDDG
HQ2746A         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
HVO_1181        ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
Hbo0378         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::

consensus       ------------------------------------------------------------
#oth            111111111111111111111111111111111111111111111111212222222222
pNG7066         ::::::::::::::::::::::::::::::::::::::::::::::::MRPDRTRNREIN
Hut1001         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
VNG0766         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP1386A         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
rrnAC0819       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
Hmu1528         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
hla2608         PLKRGVVDDEYPLGHTWPSTAERHKRVDRHGRPGPIDRPPRVLDPHCHRRAGTPCIFDEA
HQ2746A         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
HVO_1181        ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
Hbo0378         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::

consensus       -----------------METRKVQRLGPSTLAMTLPAEWAKEHDVEKGDEVSL-RMGGKG
#oth            222222222222222332421111211211111.1.11.1333313....1221.4233.
pNG7066         ARSSKSQEDKAVTPDPIRMK::::Q::S::::V:V:VD::RQ::IS:::::IVQ:DENG:
Hut1001         ::::::::::::::::::D:::::Q::::::::::::::TT:T:::::::I:I::I:D::
VNG0766         ::::::::::::::::::G:::::Q:::::::::::::::RSQ::V:::::TV::E::R:
NP1386A         :::::::::::::::MR:::::::::::::::::::::::S:QN:::::::::::::S::
rrnAC0819       ::::::::::::::::::::::::::::::::::::::::SA::::::::::::::::::
Hmu1528         :::::::::::::::::---------------::::::::SA:::::::::::::IS:N:
hla2608         YNEHRNKVKVYPAVSTS::::::::::::::::::::::::::G:N::::::::::::::
HQ2746A         ::::::::::::::::::::::::::::::::::::::::::NE:N::::::::::::::
HVO_1181        :::::::::::::::::::::::::::::::::::::::::::N:::::::TI::TS:::
Hbo0378         :::::::::::::::::---------------:::::::::::N:N::::::::::::::

consensus       TLTVLPESVQQEDSEATIHADNLDADALERAIVAQYVLGRRVIHVEAEEG-TLDSEHINA
#oth            2.1.3.112441133.3.5144121411....12......12.112453232.313111.
pNG7066         S:L:V::QPTI::V::::D::A:TP:::::::IT::::::QL:R:::TA-:P:GI::RD:
Hut1001         ::::::::::SG:T::::YVAD:::::V::::::::::::Q::::::D::A::::A::::
VNG0766         S:::T:A:AR:GET::::::TDF::::V:::::G:::::::I::::S:A-:A:::A::::
NP1386A         ::::M:::::::E:::V:::QS:::::V:::::::::::::I::::V:::G::::AQ:::
rrnAC0819       ::::M:::::T:E:::I:::E::::ASV:::::::::::::::::::P::E::E:S::::
Hmu1528         A:::::::::A:E:::I:Y:A::::::V:::::::::::::I::ID:G::E::P::::::
hla2608         :::::::::ST:E:K:V:N::G:::QS::::::::::::::::::RS:G-::::::::::
HQ2746A         ::::::::AS::::S:S:L::::N:N::::::::::::::::::I:R:DA:A::::::::
HVO_1181        :::::::::NT:::K:::R::S:N:E::::::::::::::::::I:KS:::A:::D::::
Hbo0378         ::::::::AS:::AL:::R::A:N::::::::::::::::::::I:KS:::A::::::::

consensus       VYNAETQLMGLGVIEETPERIAIRCSVDPEDFTLNNLLERLENTGSTMRGEAVKALAHGN
#oth            112..11.....11.12142121....112..2.31..1..12.1111.111121.11.1
pNG7066         IM:::RR:::::IV:QAERTVTV::::A::::D:PT::G::SR:EAVI::D:IS::IE:D
Hut1001         :::::::::::::::::::::TV::::::G::S:H:::::::S::::::N::IR::::::
VNG0766         ::S::::::::::V::::A::T:::::::A::D:::::::::::::::::::::::::::
NP1386A         ::::::::::::::::::::::::::::::::::D:::::::S::::::N:G::::::::
rrnAC0819       ::::::::::::::::::D:::::::::::::::::::::::S::::::N::::S:::::
Hmu1528         ::::::::::::::::R:::::::::::::::::::::::::S::::::N::::S:::::
hla2608         ::K:::::::::::::::SD:S::::::::::::D:::::::::::::::::::::::::
HQ2746A         ::S:::::::::::::::::::::::::::::::D::::::::::::::::GI:::::::
HVO_1181        ::K:::::::::::::::::::::::::A:::::::::::::::::::::::::::::::
Hbo0378         ::K:::::::::::::::::::::::::::::S:D:::::::::::::::::I:::::::

consensus       PDLAQRALNRERQANKIFVLLLRLIFTAYQNPNLARAVGLDSGFPLIGYRSVAKNLELTA
#oth            2..111111.11.11.1.1.1...1..2121.2121211.331...1....1.1111.4.
pNG7066         T::VETVES:QE:VE:L:Y:F:::V::I:R::R:NQ::::ET:::::::::::QDVV:M:
Hut1001         ::::::::::::::::::::::::::::H::::V::GI:::DA:::::::::::::::A:
VNG0766         :::::::::::::::::::::::::::::HD:G:::T::::E::::V:::::::::::V:
NP1386A         ::::::::::::::::::::::::::::::::::::::::S::::::::::I::::::::
rrnAC0819       :::::::::::::::::::::::::::::::::::::I::ND:::::::::I::::::::
Hmu1528         :::::::::::::::::::::::::::S:::::::::::::D:::::::::I::::::::
hla2608         ::::::::::::::::::::::::::::::::::::::::EE::::::::::::::::::
HQ2746A         A:::::::::::::::::::::::::::::::::::::D:N:::::::::::::::::I:
HVO_1181        :::::::::::::::::::::::::::S::::::::::::::::::::::::::::::::
Hbo0378         ::::::::::::::::::::::::::::::::::C:::::E:::::::::::::::::::

consensus       DNAEDIAEIVLEADGHTLDVDQSTMRRIREFTDQVDDITELAVQAVVERDYDLTIEVREL
#oth            .1.11..4113222312222135.12211122131123246215121311.131243.44
pNG7066         :T:VE::SLATDSA----TP::L:ASKLT:LG:AL::AASATRS::TTP:::A:EDA:AA
Hut1001         :::::::D:A::::::S::::AG::D:::DMVE:::K:S:Q::K:A:D:::PAA::::SK
VNG0766         ::::::::::MAT:::::::::A::::::::::A:::VAAS::S:A:N::::A:VA:::Q
NP1386A         ::::::::::::TE::::N:::K::::::::::D:NE::::G:::A:T:::::A::T:DA
rrnAC0819       :::::::::A::TED:S:N::S:::::::::::::N:::::::::A:D:N::TA:Q::::
Hmu1528         :::::::::A::S:D:::T:ES:::::::D:::::NE:::K::T:T::::::TA:::::T
hla2608         :::::::D::M::E:::::::SA:::Q::::::::::L:A::::::::::::::V:C:D:
HQ2746A         :::::::T::GD::E::::::TG:::::::::::::E::QI::N:::::N::K::TA:T:
HVO_1181        :::::::N::MD:E:::I:::::::::::::::H::E::TT::R::::::::::::C:::
Hbo0378         :::::::N::MD:::::::I:ST:::::::::::::K::AT:::S:::::::::V:C:::

consensus       FRDIRDREADILDDLP-EMDNEKLLQVREVLVSLQQTAQYAMRNAEIATNLALNEESDHV
#oth            16524222611143.21225136..441111.2.231.221211111.21..11132312
pNG7066         :DLVD::I::LNAH:E:SERP:P::ALQRAV:L:ERS:RH:RDSLSV::H::FRNDPSL:
Hut1001         ::E:DEMG::L::G:E:::P:::::A::::::G::D::::SV:::::::::::::::E:I
VNG0766         :SA:E:::::::A::::::N:AD::EA:::::::::S:::S:::::::A::::::Q:A:T
NP1386A         :A:::N::VE:::::D:::P::D::R::::::::G::::::V::::::::::::::::::
rrnAC0819       YK::G:K:HE::::::::::::A::E::::::::::::EF:V:S:::::::::::::E:T
Hmu1528         YAE:G:::TE:::::::::G::S:::::::::::::::E::V:::::::::::::::E:T
hla2608         :GRLE:::QE::GE::NDL::DT::MT::::::::H::E:::::::::A::::::P::::
HQ2746A         :QQ:S:::DE::S::::::::DN:::I:::::::::::::::::::::A:::::::CE::
HVO_1181        ::E:S:::R:::N::::::E:Q::::I:::::::::::::::::::::S:::::::::::
Hbo0378         ::::::K:R::::::D:::::Q::::I:::::::::::::::::::::A:::::::::::

consensus       TIE
#oth            226
pNG7066         :G:
Hut1001         :L:
VNG0766         :LT
NP1386A         ::K
rrnAC0819       :::
Hmu1528         E:K
hla2608         E:I
HQ2746A         K:R
HVO_1181        ::D
Hbo0378         ::G