[E] (GlnA) COG0174 Glutamine synthetase 9 genomes BUD0135 10 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG2093 rrnAC2780 HVO_0239 Hbo1259 Hmu3153 Hut2239 hla0901 NP0076A NP4376A HQ3643A

Pairwise sequence scores
Consensus score	3476	HQ3643A	NP0076A	NP4376A	Hbo1259	rrnAC2780	Hmu3153	Hut2239	HVO_0239	VNG2093	hla0901
2906	HQ3643A	3472	2789	2697	2921	2719	2728	2677	2750	2424	2469
3141	NP0076A	2789	3491	3062	2973	2861	2868	2896	2979	2517	2595
3067	NP4376A	2697	3062	3453	2880	2832	2841	2824	2914	2508	2537
3143	Hbo1259	2921	2973	2880	3487	2967	3001	2882	2958	2480	2544
3079	rrnAC2780	2719	2861	2832	2967	3674	3157	2936	2936	2473	2468
3095	Hmu3153	2728	2868	2841	3001	3157	3428	2908	2952	2490	2518
3086	Hut2239	2677	2896	2824	2882	2936	2908	3489	2985	2491	2529
3153	HVO_0239	2750	2979	2914	2958	2936	2952	2985	3512	2439	2533
2580	VNG2093	2424	2517	2508	2480	2473	2490	2491	2439	3476	2797
2667	hla0901	2469	2595	2537	2544	2468	2518	2529	2533	2797	3487

481 symbols
consensus       -----------------------TNDNAKTDGGLSAEAQAVLDEIEEKNVDFLRLQFTDI
#oth            111111111111111111333435657574223.144123.212.113311......1..
HQ3643A         ::::::::::::::::::MTDENKS:S:T::::::::::R:I:Q:::GD:E:::::::::
NP0076A         ::::::::::::::::::::::M::::VAA::::TK:::::V::::::::::::::::::
NP4376A         :::::::::::::::::::::::-----M::ES:TPDEKR:::::::::::::::::I::
Hbo1259         ::::::::::::::::::MTDDNA:SD:V:::::::K::::V::::::E:::::::::::
rrnAC2780       MSKCRRKRRNLCANQQGFSSSTAPIGCP:MTSE::EA::E:::::D::::::::::::::
Hmu3153         :::::::::::::::::::::::------MTSE:::D::D::E:::::::::::::::::
Hut2239         :::::::::::::::::::::::MTNEQV:::::::::::::E::D:Q::::::::::::
HVO_0239        ::::::::::::::::::VFRKM:E:::L::::::D:::::I::::::::::::::::::
VNG2093         :::::::::::::::::::::::MTNGDSSSSA:TDNER::::D::AQGI::::::::::
hla0901         ::::::::::::::::::::::M:DEH::P::::T:KE:::::::::E::::::::::::

consensus       LGTVKNVSIPADQAEKAFTEGIYFDGSSIEGFVRIQESDMRLDPDPSTFAVLPWRKRED-
#oth            1.11...111131.....11.........2............4...2..12....55332
HQ3643A         :::::::A::VSR:::::KD::::::::::::::::::::::K::::::::::::S---:
NP0076A         I:::::::V:::::::::::::::::::::::::::::::::I:::E:::I:::::::::
NP4376A         :::I:::AV:::::::::::::::::::::::::::::::::K:::::::I:::::::::
Hbo1259         :::::::AV::T::::::::::::::::::::::::::::::K:::E:::I::::D---:
rrnAC2780       :::I:::::T:::::::::::::::::::N:::::::::::::::::::S:::::ENVEG
Hmu3153         :::I::::V::::::::::::::::::::N::::::::::::::::E::S:::::NDGE:
Hut2239         :::::::::T:::::::::::::::::::D:::::::::::::::::::SL::::TS:::
HVO_0239        :::::::::::S:::::::::::::::::D::::::::::::E:::::::::::::K:N:
VNG2093         :::::::::::H::::::::::::::::::::::::::::::::::E::::::::SNG::
hla0901         ::V:::::V::H::::::::::::::::::::::::::::::V:::D::::::::SDGED

consensus       G-ASARLICDVINTSTGEPFEGDPRGVLKRAIERANEMGYTVNAAPEPEFFLFEEDEDGR
#oth            11311.2...132111.21.2.1..31..32151.211.1411421.......12.11.2
HQ3643A         ::R:::::::::::::::::A::::A:::ET::::::::F:I:TSS::::::::::::::
NP0076A         :::::::::::Y:::::::::::::Y::::::D::E::::SI:F::::::::::::DE::
NP4376A         ::::::M:::IY:::::::::::::Y:::Q:L:::E::::::::G:::::::::::DE::
Hbo1259         ::R::::::::::::::K:::::::Y:::Q::K:::::::KI:::::::::::::::E::
rrnAC2780       ::S:::::::::D:::::::S:::::::::::::::D::::::::::::::::::::E::
Hmu3153         S::A::::::::D:::::::A:::::::::::Q::E:::::::::::::::::::::E::
Hut2239         S::A::::::::::::::::::::::I::N::D:::::::E::V:::::::::::::::Y
HVO_0239        S::AG::::::F::::::::S::::::::::::::E:L::D::V::::::::::::::::
VNG2093         ::G::::::::VDRE-:NA:A:G::Q:::NVLA::DD:::S:SIG:::::::::K:D::N
hla0901         :S:A::I:::IVT:E-::::::G::Q::::VLSK:DD:::::SIG::::::::KT:D::N

consensus       ATTKTNDAGGYFDLAPKDLASDVRRDIIFGLESMGFEIEASHHEVAEGQHEINFEYDDAL
#oth            ...434.4..............1.21..31..3.1.21........21.1..1.2.11..
HQ3643A         ::::::::::::::::::::::I::E::H:::E:D:N::::::::::::Y::::::ES::
NP0076A         :::E:A:H::::::::::::::::::::Y:::::D:::::::::::R:::::::::::::
NP4376A         :::EFS:V::::::::::::::::Y:::A:::::::DV:::::::::S::::D:::::::
Hbo1259         ::::::::::::::::::::::::::::Y:::::::::::::::::::::::::::::::
rrnAC2780       ::::::::::::::::::::::::::::Y:::D:::D:::::::::Q:::::::T:::::
Hmu3153         ::::::::::::::::::::::::::::::::E:::D:::::::::Q:::::::T:::::
Hut2239         :::::G:H::::::::::::::::::::::::D:::::::::::::R:::::::T:::::
HVO_0239        :::V::::::::::::::::::::::::Y:::::::D:::::::::::::::::T:::::
VNG2093         :::TAH:Q::::::::::::::I::E:::T::A:::::::::::::R:::::::K:::::
hla0901         :::IPH:N::::::::::::::::KE:::T::E:::::::::::::::::::::K:::::

consensus       TTADNVATFRAVVRAIAAQHDLHATFMPKPIPKINGSGMHTHISLFTEDGENAFHDEDDE
#oth            11...11...2....1.21..1.........23.......1.3...221.2.1.1.31..
HQ3643A         :::::I::::T::::::::::::::::::::A::::::::::::::D:N:N::::::S::
NP0076A         ::::::::::T:::::::::::::::::::::R:::::::::M:::-:::::::::::::
NP4376A         ::::::::::::::::::::::::::::::::::::::::::L:::::::::::::G:::
Hbo1259         ::::::G:::T::::::::::::::::::::AR:::::::::L:::::::::::::::::
rrnAC2780       S:::::::::S:::::::E:::::::::::::::::::::::L:::::::::::::::::
Hmu3153         S:::::::::::::::::E:::::::::::::::::::::::F:::-:::::::::::::
Hut2239         S:::::::::S:::::::E::::::::::::::::::::::::::::D::::::::G:::
HVO_0239        S:::::::::S:::::::E:::::::::::::R:::::::::::::-K::::::::G:::
VNG2093         :::::I:::::::::V:E:::V:::::::::GE:::::::S:::::D:::::V:A:N:::
hla0901         :A:::I:::::::::V:S:::::::::::::AD:::::::S:::::D:::-:::A:DS::

consensus       FNLSETAKQFLAGILEHAPAITAVANPTVNSYKRLVPGYEAPVYVAWSDRNRSALIRKPA
#oth            .2..2..31131.1.3..2.11.121................1.1...12.....1.1.1
HQ3643A         :::::::HS::::V:::::::::I::::::::::::::::::::::::::::::::::::
NP0076A         :S::G::RSY:::::::::::::::::::::::::::::::::::::::::::::V::::
NP4376A         :D::D::RS::::V:::::::::::::::::::::::::::::::::::T:::::V::::
Hbo1259         ::::::::::T:::::::::::::S:::::::::::::::::::::::::::::::::::
rrnAC2780       ::::::::S:T::::K::::::::S:::::::::::::::::::::::::::::::::::
Hmu3153         :D::::::::T:::::::E::A::S:::::::::::::::::::::::::::::::::::
Hut2239         :::::::::::::::D::::::::T:::::::::::::::::::::::::::::::::::
HVO_0239        :D::D:::S:V::::D:::::::::D::::::::::::::::::I:::::::::::::::
VNG2093         :::::::Y::MG:V::::::F:::T:::::::::::::::::::I:::GV:::::::V:D
hla0901         :::::::Y::MG:::N::K:F:::T:::::::::::::::::I::::::T:::::V:V:D

consensus       ARVPAASRIEARFPDPSCNPYLAFAALIHAGLDGIEKDLDCPDPVRENIYEFDEAKREEY
#oth            .131111.1.3.1.........11.23.2...2.11522122111.11..1..121.31.
HQ3643A         ::::::::::L:S::::::::::L::I:T:::N::DDG:EA:::I:::::::::ET:M::
NP0076A         ::I:::::::L:S:::::::::::::M:::::::::N:::::::::D:::::::DT:D::
NP4376A         ::::::::::L:S:::::::::::::M:::::::::N::::::::::::::::::::D::
Hbo1259         ::::::::::::::::::::::::::::::::N:::RG:E:D::::::::::::::::::
rrnAC2780       ::T:::::::::::::::::::::::::::::::V:Q::E:D::::::::D:::E:::::
Hmu3153         ::T::::::::::::::::::::::::::::::::::E:::D::::::::::::::::::
Hut2239         :::::::::::::::::::::::::V::::::::V::EI:A:G:::::::::::::::::
HVO_0239        ::T:::::::::::::::::::::::::::::::V::G::::::::::::::::::::::
VNG2093         :A-GVSA:F:I:S::::::::::L::V:A::::::DT:A:PG:A:::D::::::D::DA:
hla0901         :A-GVSA:F:V:S:::::::::GL:SM:A:::H:::TEA:PG:::::D:::::DE::Q::

consensus       GIETLPSNLGEAVDALEADEVIQDALGEHVYEKFVEAKRQEFDEYLVDVSEWELDRYLET
#oth            ..2...52..3.221.24.2.312...3.2511.32..23.2511223..2..2.1...1
HQ3643A         ::D:::G:::::I:::DS:::::G:::D:::D::A:::T::Y::FR::::D:::::::::
NP0076A         :::::::::::::::::::::VL::::::IS:::::::T:::E:::::::::::::::::
NP4376A         :::::::::::::::::::::VL:::::::P:::M::::E::G::::E::::::::::::
Hbo1259         ::::::A:::::I:::QE:::V:::::::I::::::::S::Y::FR::::Q::::K:::K
rrnAC2780       ::T::::::::::E:::D::::::::::::::N:::::T::HK:::::::D::::::::K
Hmu3153         ::T::::::::::::::::::::::::Q::::N::D::T::Y::FR::::D::::::::K
Hut2239         ::D:::E:::::L::::D:D::L::::P:TG:::RQ:::::HK:::::::::::::::::
HVO_0239        ::::::KD::G::::::E:::::E:::D::F::::::::S::KD::::::Q:::::::::
VNG2093         ::D:::GH::D::T:::S:P:M::::::::C:::A::::H:YA::KAS:::::T:::::K
hla0901         ::::::P:::A::EE::T:::L:::::P:TS:::A:::S:::S:::TQ::Q::E::::::

consensus       F
#oth            1
HQ3643A         Y
NP0076A         :
NP4376A         :
Hbo1259         :
rrnAC2780       :
Hmu3153         :
Hut2239         :
HVO_0239        :
VNG2093         :
hla0901         :