9 genomes BUD0137 10 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG1425 rrnB0306 HVO_2325 HVO_A0048 Hbo2373 Hmu1984 Hut1803 hla1239 NP3000A HQ1959A

Pairwise sequence scores
Consensus score	713	VNG1425	NP3000A	Hmu1984	HQ1959A	Hbo2373	Hut1803	hla1239	HVO_2325	rrnB0306	HVO_A0048
418	VNG1425	728	348	330	337	381	368	394	387	349	381
418	NP3000A	348	729	356	317	381	406	382	409	408	384
487	Hmu1984	330	356	700	387	436	436	444	461	416	407
482	HQ1959A	337	317	387	693	428	443	426	430	438	473
533	Hbo2373	381	381	436	428	692	468	491	472	429	509
592	Hut1803	368	406	436	443	468	707	533	480	453	496
599	hla1239	394	382	444	426	491	533	832	494	466	525
566	HVO_2325	387	409	461	430	472	480	494	708	494	493
519	rrnB0306	349	408	416	438	429	453	466	494	703	508
588	HVO_A0048	381	384	407	473	509	496	525	493	508	709

111 symbols
consensus       ---------MPEEVLFESESRQSRAEIAAYLRTVADNLENGDAITLKAGDQSVTMEPPAR
#oth            11222212212.11..11.4622.321.22..4..13.243442..5213311.222.24
VNG1425         ::::::::::T:T:::::::T::::DV:::::::::::Q:N:T:::S::GDTE:VD:::S
NP3000A         ::MHPPLQNTM:::::KT:K:::::D::SM::::::K:DD:GDL::S:::E:::LDV:SQ
Hmu1984         ::::::::::::::::::::D:R:TDV:::::Q:::S:DADGPL::R:::::::::L:ET
HQ1959A         ::::::::::::::::K::TN:::D:::::::S::T::::AEP:::TFKSE:::::::::
Hbo2373         :::::::::::::T::K:::K:::::::T:::::::A::S::SM::S::EK:::::::SN
Hut1803         :::::::::::::::::T:QSM:::D::T::::::::::G::::::E:::::::L::::Q
hla1239         MFSPRVLTV::::::::::::R::::::::::::::S::SDN::::QK:E:::::D::::
HVO_2325        :::::::::::::::::::N::A:::::S:::::::K:DA:EP::::::::T:::::::S
rrnB0306        ::::::::::::::::K:::D:::EA::S:::K:::::DS:AD::::::SET::LA::::
HVO_A0048       ::::::::::::::::K:::G:::E::::L::R::::::::::::::::SE:::L:::::

consensus       PTFEVKAEREGPAD-GPGELSIEFELEWDENADG------GGAGDGQLEIE
#oth            22..1.....21521343...1.1.1..116333111121345442514.3
VNG1425         VD::::::::TTGGS::D:::::::::::DADHS::::AD:ETT:TG:D:S
NP3000A         ::::I:::::-TEG:SET:::V:::I:::::G:S::::::---T::DI::A
Hmu1984         VE::::::::::T:::D::::V::::::P:::::::::::-::SGSS::::
HQ1959A         ::::::::::::T:::S::::::L:I::::SSSE::::::NASEST::K:K
Hbo2373         L:::::::::::T::A:::::V::::::::DSGD::::::-:G::SS:::S
Hut1803         ::::::::::::V:::S::::::L:::::::::::::::::TE:::E:R::
hla1239         ::::::::::::DN:::::::V::::::::EG::DDDGGD::E:::E:A::
HVO_2325        :::::::::::::G:::Y::::::::::::G::D::::::-::DA:G::::
rrnB0306        :::::::::::::G:NMT:::V::::::::TD::::::::D:S:S::::::
HVO_A0048       :::::::::::::N::::::::::::::::DGSD::::::::G:N:P::::