[QR] (SmtA) COG0500 SAM-dependent methyltransferases 9 genomes BUD0180 9 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG2398 rrnAC2440 HVO_0019 Hbo1477 Hmu2740 Hut2977 hla0558 NP0956A HQ3733A

Pairwise sequence scores
Consensus score	1791	HQ3733A	Hut2977	Hmu2740	VNG2398	NP0956A	hla0558	HVO_0019	rrnAC2440	Hbo1477
1316	HQ3733A	1790	1107	1121	1156	1247	1258	1225	1163	1185
1338	Hut2977	1107	1786	1240	1106	1283	1224	1190	1179	1199
1350	Hmu2740	1121	1240	1943	1156	1262	1244	1246	1188	1325
1383	VNG2398	1156	1106	1156	1873	1225	1301	1350	1189	1267
1442	NP0956A	1247	1283	1262	1225	1802	1300	1305	1304	1395
1525	hla0558	1258	1224	1244	1301	1300	1772	1398	1316	1387
1546	HVO_0019	1225	1190	1246	1350	1305	1398	1796	1338	1418
1476	rrnAC2440	1163	1179	1188	1189	1304	1316	1338	2019	1398
1564	Hbo1477	1185	1199	1325	1267	1395	1387	1418	1398	1793

278 symbols
consensus       --------------------------------MSVRDEFDAWAADGRDRGMEDRHWHTAK
#oth            11111111111111111222212122222222...231..2..35.1.2...3.......
HQ3733A         ::::::::::::::::::::::::::::::::::::Q:::Q::NT:::::::E:::::::
Hut2977         :::::::::::::::::::::::::::::::::::G:A::Q::EQ:K:::::Q:::::::
Hmu2740         :::::::::::::::::::::::::::::::::::S:A::E::RS:K:Q:::R:::::::
VNG2398         :::::::::::::::::MPSGGVLPVGVHATP::::E:::E:::S:::K:::::::::::
NP0956A         ::::::::::::::::::::::::::::::::::::A:::::::::::::::Q:::::::
hla0558         ::::::::::::::::::::::::::::::::::::E:::E:::A:K:::::::::::::
HVO_0019        ::::::::::::::::::::::::::::::::::::::::::::::::K:::::::::::
rrnAC2440       MSITRRVRLSVDTCCYEAEIAGILRPQLLKGR::::E:::::::E:K:::::::::::::
Hbo1477         ::::::::::::::::::::::::::::::::::::::::::::::::K:::::::::::

consensus       HVLARMPVE-------------------DGDTVLDLGTGSGYALRALRETKGAGRAYGLD
#oth            21.2...1.1111111111111111111311211...1.....3....224221242.1.
HQ3733A         YA:S:::I::::::::::::::::::::::E:I:::::::::::::::::QDI:MSV:::
Hut2977         :A:G:::::::::::::::::::::::::::V:::::C:::::A::::AAG:::::::::
Hmu2740         :::::::::SEARSDSEQSSEERSDPRDE::::::::C:::::G:::::::::::V::I:
VNG2398         D::::::::::::::::::::::::::::D:::::::::::::V:::::-R:VA:G::::
NP0956A         :A::::::::::::::::::::::::::ADE::::::C:::::A::::DA:D::::::::
hla0558         ::::::::::::::::::::::::::::A::A:::::::::::::::::-R:I:::::::
HVO_0019        :A::::::::::::::::::::::::::E::::V::::::::::::::D:::I::GF:::
rrnAC2440       ::::::::::::::::::::::::::::P:::::::::::::::::::D:ND::PC::::
Hbo1477         ::::::::::::::::::::::::::::PD:V:::::C:::::G:::::::E:::V::::

consensus       GSPEMARNAREYTDDDAVGFLVGDFDALPFADDSIDHVFSMEAFYYAADPHHTLAEIRRV
#oth            21.2.24..23..114622133...45...22122..31.1..1..13..442.4.21.1
HQ3733A         :::K:VQ::::::T:SLLS:IK:::HQ:::::GT:::IW:::::::SQ::LQV:::::::
Hut2977         R::Q:::::::::::A:::::::::QH:::GT::V::A:::::I:::P::VEA:R:L:::
Hmu2740         AA::::H::SS::::PR:::AI:::EH:::D::::::C:::::::::Q:::AV:::L:::
VNG2398         :A::::A:::T:::::DLAYV::::GS::::::A::::::F::::::S::RE::::::::
NP0956A         :::::V:::::::::PQ:SYV::::GS::::A:::::A::::::::::::VGA:N:L:::
hla0558         :A::::C:::S:::::::::::::::::::::::L:::::::::::::::::::E:::::
HVO_0019        :::::VQ:::A:::T:DLS:::::::D:::D:::V:::W:::::::::::::::E::A:I
rrnAC2440       :::::L::::::::::GI:::R:::::::::T:::::::::::::::S::P:::E::A::
Hbo1477         :::::::::QS::::EKI:Y::::::E:::::::::::::::::::::::::::S:VA::

consensus       LRPGGTFYCAVNYYEENVHSHEWQENISVDMTRWSRAEYREAFREAGLHVAEQDTIPDRE
#oth            .11...1211.12321231113.2171313.21.2632...1..3..131.2.15.1.31
HQ3733A         ::S::::F::::FFD:SQ:T:R::DR:::::QL:DQTQ:::K::K:::YI::::::::E:
Hut2977         ::S::::::::D:VAD:P:TA::D:YVD:A:::::::::::::::::F:::::EA:::E:
Hmu2740         ::::::::::::RW::H::::::E:LVG:P:LL::E:Q:::::::::FA::S::R:::T:
VNG2398         :KS::::::G:::::::::::D::DS:::E::::D::T::::::G::::::A::L:A:T:
NP0956A         :::::::::::D:F::S::T:::::G:DI:::L:DYEQ:::::::::FY:::::::::::
hla0558         :K:::::::::::FA:SEQT:A:::::AI:::L:::::::::::::::Y:::::A:::::
HVO_0019        :K:::::::::::::::::::::::H::I::::::H::::::::D:::::::::S:A:LD
rrnAC2440       ::::::ANI::::::::::::::::F:DIE:::::AD:::::::::::A::A::::::::
Hbo1477         :::::::F:::::::::::::::::::::E::::TGE:::::::::::F:::::N:::::

consensus       TEIPPADEFPTDDWETREAMVERYRTFGTLLTVGVAP-
#oth            21..2134..214132.11.1111.14........322
HQ3733A         :::::::G::IEN:::::::ID::::W:::::::::::
Hut2977         V:::::A::::E::K:::::::HF:EH::::::::V::
Hmu2740         ::::AESD:::E:::::::::::::EY::::::::NTA
VNG2398         ID::A:S:::HEGFDS:AD:::::::::::::::::::
NP0956A         :::::E:::::::::R::D::::F:E:::::::::::A
hla0558         I:::D:SA::::S:HS:::::D::::W:::::::::::
HVO_0019        ID::A:T:::::::::::::::::::::::::::::::
rrnAC2440       V::::::T::::EF:::::::::::EL:::::::::TE
Hbo1477         ::::DE::::::N::::::::::::::::::::::SH: