[EJ] (AnsB) COG0252 L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D 9 genomes BUD0210 9 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG1844 rrnAC3442 HVO_2511 Hbo2170 Hmu2212 Hut0658 hla1123 NP2492A HQ2776A

Pairwise sequence scores
Consensus score	3117	VNG1844	HQ2776A	Hut0658	NP2492A	rrnAC3442	Hmu2212	hla1123	HVO_2511	Hbo2170
2465	VNG1844	3183	2191	2196	2211	2220	2265	2242	2223	2210
2410	HQ2776A	2191	3308	2043	2260	2221	2170	2224	2267	2378
2518	Hut0658	2196	2043	3100	2283	2400	2406	2220	2328	2283
2592	NP2492A	2211	2260	2283	3130	2371	2367	2326	2290	2354
2632	rrnAC3442	2220	2221	2400	2371	3129	2588	2197	2368	2319
2589	Hmu2212	2265	2170	2406	2367	2588	3164	2223	2322	2319
2551	hla1123	2242	2224	2220	2326	2197	2223	3288	2488	2411
2704	HVO_2511	2223	2267	2328	2290	2368	2322	2488	3115	2603
2648	Hbo2170	2210	2378	2283	2354	2319	2319	2411	2603	3126

461 symbols
consensus       --MNPGDRVRVERADVTNEGVLLPSSTDDHLVVKLDGGYNVGIDREDADVDVLESDVYDV
#oth            12231...12.2213323..1.2..22512..1..11.....12123.331112212211
VNG1844         MTAD:::::::THG:ASH::::V::PS:::::::::S:::::V:TA:::I:::DA:AVT:
HQ2776A         MSPH::::::::::::::::I:M::::S::::I::::::::::::A::SI:LVT::A::I
Hut0658         :::::::::A::DGER:F:::::::TDTET:::::PS:::::V:::A:EA:::::::::I
NP2492A         :::::::::::D:::::Y::::M::T::E::::::::::::::::A:::TE:::T:T:::
rrnAC3442       ::::A:::::::::AQ:Y:::::::::P::::::::::::::::::::SI::::::::::
Hmu2212         ::::A:::IH:::GAQAY:::::::::P::::::::::::::::::::T:E:V:T:::::
hla1123         :::Q:::::::D:G:::::::::::T:H:::::::::::::::::DE:::E::::GAR::
HVO_2511        ::::A::::::T::::::::::M::::E:::::::::::::::A::G:::::::T::::I
Hbo2170         ::::A:::::::::G:::::::M::T:S:Y:::::::::::::E:DE:::::::T::::I

consensus       EEAQDEEG-T----------------------SEIEFDDDLPTVSLISTGGTIASTVDYR
#oth            34334355351111111111111111111111.312.121...11...............
VNG1844         DGDTG:DAAG:::::::::::::::::::::::TV::::::::IA:::::::::::::::
HQ2776A         GGT:TDI:SSAGAGADTEADKTESDITSKSAA:AVA::ES::::::::::::::::::::
Hut0658         :PGEAS:E:-:::::::::::::::::::::::K::::E::::I::::::::::::::::
NP2492A         A:::TA:::::::::::::::::::::::::::::T:E::::::::::::::::::::::
rrnAC3442       :S::::QS:Q:::::::::::::::::::::::A::::::::::::::::::::::::::
Hmu2212         :S:::::::::::::::::::::::::::::::TV:::ES::::::::::::::::::::
hla1123         D:GA:AG:GEA::::::::::::::::::::::::T::G::::I::::::::::::::::
HVO_2511        :D::S:GDG::::::::::::::::::::::::::::::::::I::::::::::::::::
Hbo2170         ::::S:ST:::::::::::::::::::::::::::A::::::::::::::::::::::::

consensus       TGAVTAQFDAEDVLRAVPDLAGRANYRGRVVANILSENMTPAVWQDLAEAVREEIEAGAD
#oth            ..........1.......1...2........1.......1141.21..3.132..22.1.
VNG1844         :::::::::::::::::::::::::::::::::::::::E:SI:::::A:::::::::::
HQ2776A         :::::::::::::::::::::::::::::::R::::::::::::::::A::AD::R::::
Hut0658         ::::::::::::::::::E:::L::::::::::::::::::D::V:::::IH::::::::
NP2492A         ::::::::::::::::::E::::::::::::::::::::::E:::E::::::::::::::
rrnAC3442       ::::::::::::::::::::::M:::::::::::::::::::::::::Q::H::::N:::
Hmu2212         ::::::::::::::::::::::M:::::::::::::::::::::::::R:IH::::::::
hla1123         :::::::::::::::::::::::::::::::::::::::E:PI::E:::::::::A::::
HVO_2511        ::::::::::K:::::::::::::::::::::::::::::TD::V::::::A::::G:::
Hbo2170         :::::::::::::::::::::::::::::::::::::::::D::I:::::IEA:::::T:

consensus       GVVVMHGTDTMQFSASALSFMLDTPVPIVFTGSQRSADRPSSDNVMNAVCAVEAAKADAA
#oth            .1..........11.1.211..11...1.....................1..1..11141
VNG1844         ::::::::::::::::::::::E::::V::::::::::::::::::::::::::::S:V:
HQ2776A         ::::::::::::Y::::::Y:::::::V:::::::::::::::::::::::::::T::IS
Hut0658         :::::::::::::::::MA:::E::::::::::::::::::::::::::S::::::S:::
NP2492A         ::::::::::::YT:A:::::::::::V:::::::::::::::::::::::::::T::HS
rrnAC3442       :I::::::::::Y::::::::::::::::::::::::::::::::::::S:::::TS:C:
Hmu2212         :::::::::::::T:::VA::::::::::::::::::::::::::::::S::A:::S:::
hla1123         ::::::::::::Y::::::::::S::::::::::::::::::::::::::::::::::H:
HVO_2511        :::::::::::::::::M:::::::::::::::::::::::::::::::::::::::E::
Hbo2170         :I:::::::::::T:A:M::::::::::::::::::::::::::::::::::::::::C:

consensus       EVLVCMHASESDDRCALHRGTRVRKNHTSRRDAFETVGAEPLGEVDYEAEE---------
#oth            1121...1221..4....1...1..1........1.1123.1.51111355124321113
VNG1844         ::M:::::T::::::::::::::::T:::::::::::::T:::Y:::D:ASEAATA:::D
HQ2776A         G:F::::::TA::T::::::::::::::::::::K::::T:I:KIE:DT:T:::::::::
Hut0658         ::MI::::T::::A::::::::A:::::::::::::ISRA:::::::DSRT:::::::::
NP2492A         ::::::::T::::N:::::::::::::::::::::::::::::N::W:TGD:::::::::
rrnAC3442       ::::::::D::::::::::::::::::::::::::::::K:::::::DIDGEST::::::
Hmu2212         ::M::::E:::::::::::::::::::::::::::::::::::T:::::VSESDSD:::S
hla1123         :T:::::::Q:::A::::::::::::::::::::::::GA:::RI::::AAEAGADGDAA
HVO_2511        ::M::::::::::V::::E::::::::::::::::::::K::::::::::::::::::::
Hbo2170         :::::::::::::V::::::::::::::::::::::::::::::I:::T:::::::::::

consensus       ---VTFRRDHAARGE------ADLALHDDLETDVELVKFTPGMDPSAL-AAL--EGAAGV
#oth            332122313324.33111111333415431352.2.11.2..2242333153223442.2
VNG1844         ARG::VEGA:::::D:::::::T:DVASA::PA::::::::::NE:L::::C::::S:::
HQ2776A         ::::S:H::::::ES::::::TE:N:TSE:NE::M:LT:::::NIDRQT:F:TDSTPD:L
Hut0658         ::::::::EY:E:::::::::T::::Q:::::::D:::::::AG::M::DPV::::::::
NP2492A         ::::S:::PV:D::D::::::::PR:QGE:N::::::T:V::T:ADR:::VA:::::D:L
rrnAC3442       ::::::H:EYTE:DA::::::V::::::NI::::::L::S::::::L:E::A::::SE:I
Hmu2212         TDG:::::E::Q:::::::::IE:::::E:::::::::::::T:A:R:::M:::DD:::I
hla1123         DAAIEWT::PLP:::DAGEDG:SVD:EP::DG:::::::::::::A:W:DY:::DSKD::
HVO_2511        :::::::::YTP:C:::::::::::::A:I:SE::::::::::::A:::DY:::DEK:::
Hbo2170         :::I:::::::::::::::::TEFSVRS::SD::D:L:::::::LD:YADF:RGQDLD:L

consensus       VIEGTGLGHVHTDWIPRIEELVEDGTVVVMTSQCLEGRVCDRVYDTGRDLLDAGVVEAGD
#oth            111.......2112143333.33412312..1..12...............2...1.11.
VNG1844         :::::::::::S:LTDT:GS::D:::T::::::::::::::::::::::::A::::::::
HQ2776A         I:A:::::::::EF::TVA:::A::V::A:::::I::::::::::::::::E::::::::
Hut0658         ::::::::::N::::D::DA::::::A:::::::ID:::::::::::::::::::I:GE:
NP2492A         ::::::::::N::::A::D::TD:::T:::::::I::::::::::::::::::::I::::
rrnAC3442       ::::::::::N::::GT::::---DIPM:::::::::::::::::::::::::::I:GE:
Hmu2212         :V::::::::D::::EVVDD:TD:::A::::::::D:::::::::::::::A:::::GE:
hla1123         :::::::::::::L:::::A:I:N::::A::::::A::::::::::::::::::::::::
HVO_2511        :::::::::::::L::QF:::::G::::A:::::::::::::::::::::::::::::::
Hbo2170         :V:::::::::::F::VL:::::S::::T::T:::::::::::::::::::E::::::::

consensus       TLPGTAKVKLMWALANADDPADAMQEPLAGELTQRSTPWE-
#oth            1..1..2.....11116411231.33312.11142.3..31
VNG1844         ::::::::::::::::::::EA::::SV::A::TQ:R::TA
HQ2776A         ::::::::::::::::HP::TN::RKS:::::QH::V::::
Hut0658         M:::::M:::::V:::R::::A::G::::::I:E:::::::
NP2492A         :::A::Y:::::::EH::SV:E:::R::::::QE:::::T:
rrnAC3442       M:::::::::::::::S::V::T::::::::IQ::::::L:
Hmu2212         M:::::::::::::::TS:V::T:S::::::IQSQ:R::T:
hla1123         ::::::::::::::::LS:::E::GRD::::::EE:Q::R:
HVO_2511        ::::::::::::::::VA::T:::GRN:E:::::::V::::
Hbo2170         :::::::::::::V::LE::EE:::QS:S:::::::V::::