[J] (-) COG2016 Predicted RNA-binding protein (contains PUA domain) 9 genomes BUD0212 9 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG2646 rrnAC2087 HVO_0390 Hbo1113 Hmu0232 Hut0829 hla0481 NP0340A HQ3178A

Pairwise sequence scores
Consensus score	1186	HQ3178A	VNG2646	NP0340A	Hut0829	rrnAC2087	Hmu0232	hla0481	HVO_0390	Hbo1113
788	HQ3178A	1172	653	722	679	746	707	738	784	801
862	VNG2646	653	1187	716	756	801	759	754	792	781
888	NP0340A	722	716	1194	761	837	803	790	806	803
894	Hut0829	679	756	761	1249	815	850	842	804	793
979	rrnAC2087	746	801	837	815	1199	995	798	864	836
1002	Hmu0232	707	759	803	850	995	1187	796	858	863
910	hla0481	738	754	790	842	798	796	1550	867	820
990	HVO_0390	784	792	806	804	864	858	867	1169	896
977	Hbo1113	801	781	803	793	836	863	820	896	1190

214 symbols
consensus       -----------------------------------------------MNVKSRHHLRSDE
#oth            11111111111111111111111111111111111111111111111.4.1......2.2
HQ3178A         ::::::::::::::::::::::::::::::::::::::::::::::::Q::::::::T::
VNG2646         ::::::::::::::::::::::::::::::::::::::::::::::::D:S::::::::D
NP0340A         ::::::::::::::::::::::::::::::::::::::::::::::::Q:::::::::::
Hut0829         :::::::::::::::::::::::::::::::::::::::::::::::::::::::::A:A
rrnAC2087       ::::::::::::::::::::::::::::::::::::::::::::::::E:::::::::::
Hmu0232         :::::::::::::::::::::::::::::::::::::::::::::::::::::::::A::
hla0481         MKVPTVLRTTATFSATATSSATAAPSATATITPWSGPFIGRAVDWVC:E::::::::::D
HVO_0390        ::::::::::::::::::::::::::::::::::::::::::::::::K:::::::::::
Hbo1113         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::

consensus       IDAIEEALAANLGVELDGDAYEKVEFADADWEVVLVDGDPLVLYVDDE--------PFLT
#oth            122143323661..4311121.5.113133322..1113131524312211111111.1.
HQ3178A         ::TLTAEIEHTT::A::A::::L::LDGVSYN:::A:DNLDIVRF:::::::::::::::
VNG2646         ::E:GD::RTG:::::::::::R:T:::EEF:I:::::::::W:P:G:::::::::::V:
NP0340A         :::L::R::DR:::TP:::S::R:::D:V:R:::::::E:::ASF::D::::::::L:::
Hut0829         ::E::D:::KG::::::AET::::T:E:S:::::::E:A:A:F::P:DESPDSTDD::::
rrnAC2087       V:T:TT::SE:::::::A:SF:::::D:S::D::::::::::::LNG:::::::::::::
Hmu0232         ::::::SV:::::::::A:TF:::::E:S::D:::::::::::::EG:::::::::::::
hla0481         :T::R::V:DH:::DI:::TF:F:::V::NY:L:::::E:A:F::::DE:::::::::::
HVO_0390        :::LCDSIESS:::A:A:::F:A:::::::Y:::::::E:A:M::::Q::::::::::::
Hbo1113         :SEL::EI::QT::QM::::::M::L::::FD::::::::V:V:M:::R:::::::::::

consensus       VRGANAYPPTTNVVTVDAGAISFVSDGADVMRPGITEADDDIEAGDLVVIAEETHGKVLA
#oth            .4.1.425.4531....1..1....3..11.....12.354.531.112.4.13.2.3.1
HQ3178A         :Q:::R:N::RS:::::::::::::N:::::::::VD:ETA:D:::F:L:V::::N::::
VNG2646         :A:::RTD:S:G::::::::V:::::::::::::::A:SPE:T:::::::Q:AA:::T::
NP0340A         :::::E:A:DSH:::::S::V:::::::N:::::::::TA:::P::::::V::A:::A:G
Hut0829         :::::E:Q:AQ::::::S:::::::::::::::::V:::ES:DS:::L::S::N::::::
rrnAC2087       :Q:::Q:::EKHI:::::::V::::::::I::::::::::::S:D:::::N::S:::F::
Hmu0232         :E:L::::::DH:::::S::::::::::::::::::::::G:A:::::A:N::S:::F::
hla0481         :::::D:E:E:GI::::::::::::G:::::::::V:::SA:RE:::::::::::E::::
HVO_0390        :K:::QF:::::::::::::V::::S:::::::::::::ES:::::::::::::::::::
Hbo1113         :A:::::E::K::::::::::::::::::::::::VD::::::P::::L:::::::::::

consensus       VGRALVDGDDMVGDSGKVVESIHHVGDDLFEFSV
#oth            1...432.3413.11....311.....1.11.21
HQ3178A         I::::::::ELI:::::::::::::::::YS:::
VNG2646         ::::::::TE:D:E:::::S:L:::::E::::::
NP0340A         ::::EA::::::::::::::TL:::::::Y::H:
Hut0829         ::::R:::SA:L::E::::DT::::::E:Y::AG
rrnAC2087       ::::QT:::::::::::::K:L::::::::::::
Hmu0232         ::::KAS::G::::::::::::::::::::::::
hla0481         :::::::::N:::::::::::::::::E:Y:::G
HVO_0390        :::::E::A:L:::::::::::::::::::::::
Hbo1113         :::::EP:AE:::::::::::L::::::::::A: