[T] (UspA) COG0589 Universal stress protein UspA and related nucleotide-binding proteins 9 genomes BUD0227 9 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG2520 rrnAC2220 HVO_1823 Hbo1660 Hmu0430 Hut1660 hla1102 NP1430A HQ1066A

Pairwise sequence scores
Consensus score	1090	HQ1066A	rrnAC2220	Hmu0430	NP1430A	Hut1660	VNG2520	hla1102	HVO_1823	Hbo1660
719	HQ1066A	1161	574	490	565	609	612	635	626	696
744	rrnAC2220	574	1129	787	543	655	585	664	620	619
666	Hmu0430	490	787	1091	527	642	543	586	613	589
690	NP1430A	565	543	527	1154	527	623	609	667	621
776	Hut1660	609	655	642	527	1107	629	648	678	711
811	VNG2520	612	585	543	623	629	1148	797	770	752
879	hla1102	635	664	586	609	648	797	1300	801	768
901	HVO_1823	626	620	613	667	678	770	801	1106	893
903	Hbo1660	696	619	589	621	711	752	768	893	1126

182 symbols
consensus       -------------------MFDTVVIATDGSASVRRAVDVALDLAARFDATVHALYVVDA
#oth            1111111111122212222.21.1.2.....4114...3321.2.52.1.3..21..213
HQ1066A         :::::::::::::::::::::E:I:::::::E:::::::TG::I:S:::::::C:::::E
rrnAC2220       :::::::::::::::::::::::::::::::G:AE:::EA:::::::::::::G:::::T
Hmu0430         ::::::::::::::::::::::::::::::::TAE:::TA:::::GQ::::::::::::S
NP1430A         :::::::::::::::::::::E:::V::::::::S::::CT::::SK::::::::::::E
Hut1660         ::::::::::::::::::::Y::::L:::::Q:AD:::T:G::::R:::::::::::T::
VNG2520         :::::::::::MPRGKHTA:I::::::::::E::G::::::::V::::::A::::::LE:
hla1102         MPYRTRPPVFNYHLGERVR::::I:::::::D:::::::::V:V::::::E:::V::::S
HVO_1823        :::::::::::::::::::::::I::::::::::::::S::V:::E::::S:::::::::
Hbo1660         :::::::::::::::::::::::I:V:::::E:::::::::::::D::G:S:::::::::

consensus       GEVESS-PDEVRDDLRDALAERGERALSQVAEA-----ADREVTTAVREGRPAAEICAYA
#oth            2322441.4422334252.533.35114535422322233532322213.3.333147.1
HQ1066A         NNTD:NK:LSDS:NDQMT:Y:H::K:VNT::GR::::::NH::I::IKH:N:SDK:E:::
rrnAC2220       ::::TT::E:::EA:ER:::TT:G::::FIL::ADAE:::E:LV::::::D::D:::T::
Hmu0430         :::AG:::EA::EEFEQ:::TT:GK::TFAR::AEAEEEEDA:V:T::::D::K:::R::
NP1430A         :HL:EL::TDLEG:I::G:D:Q:QQ::NDIVA:NERREDPV:LE::::V:H:EKQ:VG:V
Hut1660         S::DA:::AA:::::EA::QQH::DV:A:LTQQ:::::T::S:V::::::::::::::::
VNG2520         SD:::A::::::T:M::::E:::KD:V:A::DR:::::::VS::::::A:::P:::SQ::
hla1102         :::::T:::::::::::::DDH::A::D::TD:ATARD::LDI:IEA:::::::::SK::
HVO_1823        :D::TA:::RL::EM::::T::::E::AE:EA::::::T:::::V:::::::::::SN::
Hbo1660         S::D::::ERL::EM:E::T:::Q::::E:E:::::::T::S:::::::::::TVVGD::

consensus       REVDADVVAMGTRGRHGENRFLIGSVAERVVRTCPVPVLTVRQLEEDET------TPERA
#oth            3121..3112.....1..131.1.....41..2213........3344224123133353
HQ1066A         :DI::::I::::::::::::::::::::KL:::A:L::::::::AA:::DERLSG::::M
rrnAC2220       M:H::::IVS::::::::HGY:L:::::EL::EA:M:::::::::GEP-::::::N:::T
Hmu0430         E:I::::I:T::::::::HGY:L:::::G:::RAEM::::::::::AT-::::::NGL--
NP1430A         :D::::GI:::::::S::HS::L::::::::::::::::::::::GAAD:::::::A:A:
Hut1660         Q::A::::VT::::::::HA::L:::::A:::RS::::::::::DA:::SA:V::::QE:
VNG2520         :D::::A::T::::::::::::::::::::::::::::::::::ADT--::::::DA:QT
hla1102         ::I::::::::::::::::::::::::::::::::I::::::::TDE--::::::D:R:T
HVO_1823        ::::::A:::::::::::::::::::::::::::::::::::::::GT:DS:LL:SD:A:
Hbo1660         ::::::M:::::::::::::::::::::::::::::::::::::A::::DG:LEG:::S:

consensus       --
#oth            34
HQ1066A         ::
rrnAC2220       EV
Hmu0430         ::
NP1430A         GG
Hut1660         ::
VNG2520         TA
hla1102         TI
HVO_1823        ::
Hbo1660         ::