[T] (UspA) COG0589 Universal stress protein UspA and related nucleotide-binding proteins 9 genomes BUD0236 9 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG2521 rrnAC2221 HVO_1822 Hbo1661 Hmu0431 Hut1661 hla1321 NP1718A HQ1065A

Pairwise sequence scores
Consensus score	1085	Hut1661	rrnAC2221	Hmu0431	NP1718A	VNG2521	HQ1065A	hla1321	HVO_1822	Hbo1661
632	Hut1661	1102	517	522	481	513	461	508	505	470
652	rrnAC2221	517	1439	700	450	477	454	471	469	397
667	Hmu0431	522	700	1085	495	513	477	511	495	438
575	NP1718A	481	450	495	1052	510	506	509	529	512
653	VNG2521	513	477	513	510	1071	520	553	583	537
765	HQ1065A	461	454	477	506	520	1088	668	712	745
791	hla1321	508	471	511	509	553	668	1083	735	685
830	HVO_1822	505	469	495	529	583	712	735	1088	803
780	Hbo1661	470	397	438	512	537	745	685	803	1099

196 symbols
consensus       ----------------------------------------------RPLDIDLVLVPVDG
#oth            111111111111111111111111111111111111111111234535231111.111.3
Hut1661         ::::::::::::::::::::::::::::::::::::::::::::::MAVE::TI::::::
rrnAC2221       MTTVSNIHHASKPRLNTLLVTARDSPYDTTLPARTPVDFCRPGSQW:VM::::::A::::
Hmu0431         ::::::::::::::::::::::::::::::::::::::::::::::--M::::::A::::
NP1718A         ::::::::::::::::::::::::::::::::::::::::::::::--M:V:T:::::::
VNG2521         ::::::::::::::::::::::::::::::::::::::::::::::M::TV:T::A::::
HQ1065A         ::::::::::::::::::::::::::::::::::::::::::MTEN:L:SV::I:A:I:A
hla1321         :::::::::::::::::::::::::::::::::::::::::::::MTD::::::::S:::
HVO_1822        :::::::::::::::::::::::::::::::::::::::::::MSP:::S:::::::::Q
Hbo1661         ::::::::::::::::::::::::::::::::::::::::::MSDR::::VN:::::::R

consensus       SEESERAVEYAAAIAARYDAAVHALYVLDEDVVRAIETGDVDADAVAADHQAFTDSVRAR
#oth            124175.121.441.23.1.43.3121221334232241413342114435324333653
Hut1661         TDR:D:::KH:LP::D::::E::I:::IE:T:AAGL:Q::IE::S::NE:R::M:A::EQ
rrnAC2221       :DQ::::A:::I:V:E::::DL:L:F:I::RLHQD:DS:::S:T:I:EE:::::E:I:D:
Hmu0431         :NQ::A:::::L:::DA:::EI:L:F::::TLI::::ADE:::::I:DQ::V:AAEMQS:
NP1718A         ::TAMD:::::VE::D::G:G:::::LVG:NAAAEM:A:A:::TDI:TRGEQIMA::::I
VNG2521         TDA:VT:A:::VTV:D::::DA::::::G:T:T:::G::::AE:D:::GTNT:LNEIA:L
HQ1065A         ::::LD:::::SV:::K:::S::VVH:::::I:Q:::::T::KS:::T:G:TI:E:AETI
hla1321         ::::HE::D::I:V::E:::S:::::::::::::::DH:V::EGD::D:TE::::::VR:
HVO_1822        :::AT::A:::::V::E:::::::VH::G::::::::Q:V::E::::E:SK:V::T:S:L
Hbo1661         ::::AN:::H::::::E:::::::VH::GG:::::::::A::DED:V::ST:IQETAGEI

consensus       AAD--HDVALSTSVAYGFSTTRKTQHPGSVVLDTAEDLDADFIVVPREPVSGDPGEVLGK
#oth            354223436454.31411.4441432.11.1..2.12142..2.1..2333214332231
Hut1661         VRADG:NID::Q:TVF:Y:ASSL:R::V:::::A:::IG:::::I::QS:MDE::AM:::
rrnAC2221       FR::A::GVFE::S:TA::E::LM:T:::::::V:::::S::::::::EG:EE---AV:R
Hmu0431         LD:RG:EAG:NH:T:A:::P::LR:S::::I::V:::::::::::::::G:D:SVDAI:R
NP1718A         :GT::--:PVDH:S:C::::C:LS::::::I::V::M:AV::V::::Q::T::EEA:IE:
VNG2521         :P:::-G::VDS:I::::::S::R::::::I::A:A:I::::V:I:::GMREET:D::ER
HQ1065A         ::K::Y:ISA::::V:::::QI::T:::R:::::::::N:::L::::K:L::::::::SR
hla1321         :EA::AGI:H:N:I::::::KV::V:::::::::::E:ES::::::::::::::::::::
HVO_1822        :ET::A::PVT::::::::R:S:LR:::::::::::E:::::::::::::::::::::A:
Hbo1661         ::R::Y::E:A:::::::::KM:LR:::::::::::E:G:::V:::::::::::::::A:

consensus       AAEYVLLYASQPVLSV
#oth            1.2..13.......1.
Hut1661         V:::::T:::::::::
rrnAC2221       ::I::IE:::::::T:
Hmu0431         ::L::IE:::::::::
NP1718A         :::::IA:::::::::
VNG2521         ::::::::::::::::
HQ1065A         ::::::::::::::::
hla1321         ::::::::::::::::
HVO_1822        ::::::::::::::::
Hbo1661         ::::::::::::::::