9 genomes BUD0238 9 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG1874 rrnAC3414 HVO_2584 Hbo2263 Hmu2371 Hut0968 hla1491 NP2428A HQ3214A

Pairwise sequence scores
Consensus score	1289	HQ3214A	hla1491	HVO_2584	Hbo2263	NP2428A	VNG1874	Hut0968	rrnAC3414	Hmu2371
785	HQ3214A	1314	748	721	744	515	432	542	581	586
857	hla1491	748	1564	830	861	520	557	610	663	631
933	HVO_2584	721	830	1356	953	512	545	614	632	612
933	Hbo2263	744	861	953	1309	517	598	642	688	615
683	NP2428A	515	520	512	517	1237	515	605	559	594
774	VNG1874	432	557	545	598	515	1309	640	696	698
860	Hut0968	542	610	614	642	605	640	1317	778	714
880	rrnAC3414	581	663	632	688	559	696	778	1314	916
878	Hmu2371	586	631	612	615	594	698	714	916	1317

214 symbols
consensus       ---------------------------------MYAVVGCSDCSALWLLED--RPETAQC
#oth            1111111111111111111111111111112231.2....33.422.234124323125.
HQ3214A         ::::::::::::::::::::::::::::::::::::::::TN:::M:::S:AHTA:S:T:
hla1491         MEATIPHIELDCILIDSATQVRGFKSGGDEPRG:::::::NE:A:M:::M:PQTSDS:R:
HVO_2584        ::::::::::::::::::::::::::::::::::::::::T::ANM:::S:PDGSK::T:
Hbo2263         :::::::::::::::::::::::::::::::::::::::::E:GSM:::T:PRQSK::N:
NP2428A         :::::::::::::::::::::::::::::::::::T::::PA:R:I:VV::::::::TE:
VNG1874         ::::::::::::::::::::::::::::::::MS:::::::::N:::VVAG::::::TS:
Hut0968         ::::::::::::::::::::::::::::::MTA::S::::T::::::VI:G::::::S::
rrnAC3414       :::::::::::::::::::::::::::::::::::::::::E:::::VT:G::::::T::
Hmu2371         :::::::::::::::::::::::::::::::::::::::::::::::IV:G::::A:T::

consensus       PRCGRRHQTKKLRKFVETDDRDAARQARAALLAKRQGDGEAFADLDHVSEMERAV--DEA
#oth            1..12112242114.32221221.121.112..31415121.244333332355311343
HQ3214A         :::::T:::::::H:::ES::E::::::S::::::D:NSA::::TA::AK:::TLAD:TQ
hla1491         ::::KT:::T::KR:F:SE::E:::E::::::::KRDESA:::E::::::L::::::::S
HVO_2584        :::::::::::::R:F:S::::::::::S:::::KH::S::::QVE::::LD:R:::E:S
Hbo2263         :::::T:::::::::L::E::E::::::::::::KH::S::::KTA:I::::SL:::E:S
NP2428A         R:::K::RFG:::S:AQ::TA:::ARV:SSM::D:AD::A-:V:PQTI-----DI::EGV
VNG1874         :::ET:::FGT:KQ::T:::E:H::EV::SI::NKA:Y::::::M:GFTALGEDA::MA:
Hut0968         ::::K:R:FDL::::AQ:ETA:::::::::M::E::DL::::DG::SYA:::A::::S::
rrnAC3414       ::::T:RKHE:R::::::::EAH::EV::SM::N:::E:D:::E::SYA::::Q::::D:
Hmu2371         ::::TTRKHE:R::::::::E:H::EV:SSM::N::DH:::::E::SF::::GRL:::D:

consensus       GIDDAEYLEASGVDADEVAAAGERAE-G---ASGSRSRLEIVRAALRELDAPTEEEVVAY
#oth            221.432.233.21321144.1442441111544242.6322241235513.1.331243
HQ3214A         QVS:N:::SGV:INP:A:EN:AQSDD:-:::-ATRQ::P::I:S:ISSQ::::::DIIS:
hla1491         ::::R:::::::I:::A:DE::A:::G::::E:D::::S::::D:VATV:E::::N:::H
HVO_2584        :V::R::::G::L:::::FE:::A:AR:RDSS:::PD::TV::E:I:DG:R:::::I::A
Hbo2263         ::::::::::::L::::::S:::Q:MQ::::QTS:SN::DV::E:::KE:R:::::::::
NP2428A         :::::TF:S:::::P:A::D:::TDT:-:::-::::::KR:LLDG:S:::::::A:::E:
VNG1874         ::::DD::D:A::::A:A:::::::::::::TRR::::QDT:::::::::E:::R::A:F
Hut0968         V:::D::::SK:::S::A:D::R::TE:::::G::T::E:::::::V:::D:D::AI:E:
rrnAC3414       :V::ET:::D::::T:A:S::AD:::Q:::::T:GS::K:T:TN:::A::E:::DDI:G:
Hmu2371         :PS:EAV:::A:::TE:::::A::S:G:::::G:GQ::T:::LS::::CE::::AD:ID:

consensus       ATERGVPADYARDALAKLRRAGEVSESRGTYRLL
#oth            .422..14442243.52.4.2.222133132.21
HQ3214A         ::D::::T:A::EL:E::I:Q:NLT::H::::::
hla1491         :SDH::::ET::EI:TR:A:R::L:::G:R::A:
HVO_2584        :V:::::::R:::L:D::::R::::::::RH::V
Hbo2263         :E:H:::GEA::NV:E::T:R::::::::R::::
NP2428A         ::AA:::EAK:ERL:T::::::::T:TD::L:R:
VNG1874         :A:H::GSE:VA::::::T:::::VDAGDG::::
Hut0968         :A:::::EK:T:R::SS:V:::D:::N::::::V
rrnAC3414       :E::::::S:T:K::K::V::::A:::::H::::
Hmu2371         ::::::::::V:::::::::R:::T::G::::R: