[H] (MoaE) COG0314 Molybdopterin converting factor, large subunit 9 genomes BUD0249 9 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG0081 rrnAC1186 HVO_1864 Hbo1739 Hmu2945 Hut0723 hla0890 NP2274A HQ1099A

Pairwise sequence scores
Consensus score	1985	VNG0081	hla0890	HQ1099A	HVO_1864	Hbo1739	NP2274A	rrnAC1186	Hmu2945	Hut0723
1191	VNG0081	2259	827	822	879	864	916	979	1026	956
1180	hla0890	827	2202	854	968	940	966	906	930	921
1109	HQ1099A	822	854	2012	955	1064	914	862	891	917
1319	HVO_1864	879	968	955	1936	1191	987	1048	1069	970
1216	Hbo1739	864	940	1064	1191	1957	958	950	993	936
1224	NP2274A	916	966	914	987	958	1969	953	1001	983
1395	rrnAC1186	979	906	862	1048	950	953	2088	1273	1287
1457	Hmu2945	1026	930	891	1069	993	1001	1273	2065	1302
1419	Hut0723	956	921	917	970	936	983	1287	1302	2033

336 symbols
consensus       ----------------------------------MQVLGIVG---AGATALAERLAARLD
#oth            1111111111111111111111111111111111.332223.2223122213432454.3
VNG0081         MLPVVARCWSRAGGPVVPTAQRATLITPARQRTR:KA:SV::PA::DTD:A:AAV::A:R
hla0890         ::::::::::::::::::::::::::::::::::::PIS::::::P:::D::GT::D:::
HQ1099A         ::::::::::::::::::::::::::::::::::::::::L::::QD:G::CSDVI:Q::
HVO_1864        :::::::::::::::::::::::::::::::::::H:::::::::::::T:CD::::Q::
Hbo1739         :::::::::::::::::::::::::::::::::::H:::A:::::P:::::L::IIPH::
NP2274A         :::::::::::::::::::::::::::::::::::YTTVV:::::SD:D:A::::VST::
rrnAC1186       ::::::::::::::::::::::::::::::::::::::::::HSDS:K:T:V:::TQ::S
Hmu2945         :::::::::::::::::::::::::::::::::::H:::VA:PSD::K:T:V::VCE::A
Hut0723         :::::::::::::::::::::::::::::::::::::I:VT:PSN::K:T:V:A:VE::S

consensus       --GRVATVKHCDEAPT-------------------VDTDGKDT-----AGAATAYGLADD
#oth            32.2.1113565575411111111111111111114653562333335343343241432
VNG0081         PR::::::RRD:TVT::::::::::::::::::::PAS-----:::::--T:RSVS:S:H
hla0890         ::::::V:DCGG:DGERGEAPGRAAESEVTDGGVA:RR:DS:DEGAAERA:D::IA:DA:
HQ1099A         :::A::VI:TQETIDQ:::::::::::::::::::TFN:PHN:::::SSDVT:R:D:::T
HVO_1864        ::::::::ESLP:SA::::::::::::::::::::-EPEST:-:::::-:V:A::::SP:
Hbo1739         ::::::::ESG:WNDE:::::::::::::::::::PTPLSD--:::::--VE:::T:G::
NP2274A         :::::GV:R-------:::::::::::::::::::---EAA:PADGST:VG::T:T:G-:
rrnAC1186       GT:::::::::TH::D:::::::::::::::::::::::::::VRHRD::::ETVA:T::
Hmu2945         ER:::::I:::TH::D::::::::::::::::::::::E::::ARHRA::::VS::::::
Hut0723         ER:T:G::::V:CE:::::::::::::::::::::L:::::::ARHRA:::DRT::I:-:

consensus       GSWRASGEDRTLDDALDDLSPDHDYALVEGFSDARIPTVALGDA-----DDADNVVAAAE
#oth            25.413.64341234.24.13541.32231434343.21212451222233245523323
VNG0081         :A:A:::A::::::V:A::A:AF::VI::::P::AL:::::::H::::::VP:PD:-T:P
hla0890         :::AGR:RVEG:::L::G:A:::::LVAV:E:RL:V:::L::AD:AEPA:VPGS:::::D
HQ1099A         :H::::::NHSVV:I::E::TTV::T::I:A:N::::::L:ET:VTDIDH:STH::LT::
HVO_1864        :N:VG::D::D::GL:::::AEY::::LS::P:::V:::::AGV:::::-::A::::E::
Hbo1739         S::::::TE:P:ERV:::::TR:::::LSR:PE:TV::::::G::::::-::A:A:LE:A
NP2274A         :-:::D:G:LSV:G:::R:A::::::::V:VDGV:G:::VA::Y::::D::PE:LL::::
rrnAC1186       :E:Y:T:QS::::ET:::::::Y::V::::Y:::N::K:V:::R:::::EA::P:IHRTP
Hmu2945         A-:F:T::::G::ET::E:ARSY:::V:::Y:G:::::::::GR::::::H:GRRL::G:
Hut0723         :::FGT::S:::::::EA::T:CA::I:::YA:IDL:QIV::H::::::-:::GML-::A

consensus       TADDLDLEDIVAAIEDAEPYETLESLVARVKASPDADRAGAIATFTGRVRARDDPDDDPT
#oth            62333.324333434362132.132.1352132322221...........221342.42.
VNG0081         N::A::T:AVL::V:::PVR:::D::::SL:SHE:SEF::::::::::::E::::::T::
hla0890         AP:QI::DGL:TDLA::::WV:R:A::RQ:E::A:::::::::::::::::::A:N::R:
HQ1099A         ::TAI:T::V:T:::S:::HI::ST:ID:::S:S:::::::::::::::::::SD::PE:
HVO_1864        :::AA:VASLA:E:DSH::HV:::T::E:A::D:LEVY:::::::::::::KESE:::::
Hbo1739         DG:E::TD:::::M:AS::HV::ST::EQ::Q::R::::::::::::::::KEGD::AR:
NP2274A         R:A:::A:Q:QDGLQET:::::::::::A::R:::::Y:::::::::::::KE:A::ER:
rrnAC1186       HGA:A::D::LT:M:ERD::I:::T:::D::RD::EVYS::::::::::::QEG:E:P::
Hmu2945         ::S:V:AAAL:E:LH:C::::::G:::::::::S:S::::::::::::::E:::H::T::
Hut0723         S:A:V::::A:EV::SVD:::::S::::E::R::::::::::::::::::RK:S:::E::

consensus       EHLEFEKYDGVAEEKMATIREELEARDGVFEVRLHHRTGVVEAGEDIVFVVVLAGHRREA
#oth            56.3..2.14..3321221452152....33.411.11.2131.2.1.2111.....511
VNG0081         Q:::::R::T:::QR::::::Q:CE::::YD::M:::::::P::D:V:H::::::::GD:
hla0890         T::A::::E:::A:Q:DA:AA::TE::::::::M::::::I::::::::I:::::::G::
HQ1099A         VR:R::T::S::DDR:RE:ES::SE:::::A:E:F::::IIND::::::::::::::A::
HVO_1864        LS:::::::::::S::DA:S:::::::::LR:LM:::V::::D:A:::::::::::::::
Hbo1739         TQ:T::::::::::::R::ES:IA:::::E::TMF:::::I:D::::::::::::::::S
NP2274A         RF:::::::A::D:R:D::AT:::Q:::::::L::::::R:PD::::::::::::::D::
rrnAC1186       :L::::R::E::A::::AL:RD:::::::YA:::::K::::D:::::::::I:::::T::
Hmu2945         :Y::::::E::::::L::::DD:C::::::::A:::::::::::::::::A:::::::::
Hut0723         :Y::::R::E::TDQ::::Q:::R::::::D:::::::::::::::V:Y::::::::K::

consensus       FRTVEDGIDRLKDEVPLFKKEVTVDEEFWVHER---
#oth            .11.1...1.1.2...1..1.2.33131.2.21421
VNG0081         ::A:S::::::::::::::::::::DA::R:DIPE:
hla0890         ::::::::::::::::I::::S:EA::::::R:E::
HQ1099A         :E::S:::N:::A:::I::H:T:IE:D::::::N::
HVO_1864        ::::::::::::::::I::::T:T:::::::D::::
Hbo1739         ::A:::::::::::::I::::T::E:D::::D:D::
NP2274A         ::::::::N::::::::::::::EA:T::::::DDR
rrnAC1186       ::A:::::N:::E::::::::::::::::A::::::
Hmu2945         ::A:::::::::::::::::::::EDAV:A::::::
Hut0723         ::::::::::I:A:::::::::::S::::A::::::