[J] (-) COG1325 Predicted exosome subunit 9 genomes BUD0282 9 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG1287 rrnAC1178 HVO_1249 Hbo0296 Hmu1467 Hut1218 hla2382 NP3528A HQ1808A

Pairwise sequence scores
Consensus score	1061	VNG1287	HQ1808A	HVO_1249	Hbo0296	Hut1218	hla2382	NP3528A	rrnAC1178	Hmu1467
753	VNG1287	1064	576	654	662	606	666	611	670	650
744	HQ1808A	576	1109	734	766	610	644	580	650	648
821	HVO_1249	654	734	1081	836	614	689	646	659	648
807	Hbo0296	662	766	836	1118	631	701	673	643	655
771	Hut1218	606	610	614	631	1059	626	723	705	679
835	hla2382	666	644	689	701	626	1311	696	709	739
769	NP3528A	611	580	646	673	723	696	1100	682	752
831	rrnAC1178	670	650	659	643	705	709	682	1065	828
837	Hmu1467	650	648	648	655	679	739	752	828	1038

176 symbols
consensus       MSSVPFHYVDLRAFCYATEDEKRVEDALRTFLPEDFELERAESEGHHGDRIIVLSARVER
#oth            .251....1...2.2.2..132..24.13231.11422215413..2....3.3.2.2.2
VNG1287         ::E:::::I:::V:::D::ADS::A:::GH:::::V:I::TD::::L::::G:::T::::
HQ1808A         :PQI::::I:::T:S:E:::::::NS::Q:I:::::P:T:M::S:::::::::F:T:::S
HVO_1249        :PR:::::I:::T:::E:::Q::::G:::::::DE:DVD:V::T:::::::::F::::::
Hbo0296         :PR:::::I:::T:::E::::::::A:I:SL:::E::I::I:NT:::::::::F::::::
Hut1218         ::::::::::::::::::::SA:::S::::LM:::A:::QTA:::::::::L:H:T:L::
hla2382         :AT:::::::::::A:::::::::A::::::::::T::D:V:NV:::::::V:::::I:N
NP3528A         ::A::::::::::::::::::::::A::E:::::ET::::EVN::::::::L:Y:V:L::
rrnAC1178       ::::::::::::T:::::::D::::::::::::::YPV:::Q::::Y::::::::::::N
Hmu1467         ::::::::::::::A:::::::::AE::Q:Y:::ET::::::::::Y::::V:::::::N

consensus       ADDIRHVLDQLADLD--DFETLLDELDERVDDNCSFFLRLDKQAAFGGEVRRGDGITLRA
#oth            .132.1..32234441124152331.12.112.12112322....1535322.3.122.1
VNG1287         :::M:::::::R:GA:::I:QIR:Q::::::::::L:VH::::::YL:DAQL::::S:::
HQ1808A         ::A:::::I:::R:P::S::::QS::::::TE:TEL::::::::::R:MI:::E::::::
HVO_1249        :N:V:Y:::KIR::P::::::::::::Q::T::TE:::::::::::K::A:::G:L::::
Hbo0296         :NEV::::SK:S:IQ:::::G:::::::::TE::EL:M::::::::RD:T:L:::::F::
Hut1218         ::E:::::S::GA:EPSER:D::A::E::::::T::::T:S:::::N:R:E::::::::G
hla2382         ::GM:::::R:SE::::EVDRVI::::Q::::::AL:::V:::::::::::L:P:::V::
NP3528A         :::V::::SRV:E:::::::R::S::EQ:I::::A:Y:QF:::::YQNR:EF::::M::G
rrnAC1178       ::::::::T:V:SAP::EIDAVRA:::D::::::::::TFG::::::RN:E:::::::::
Hmu1467         ::::::::T:V:AV::::L::V:E:::D:::A::::::TF:::::::NS:E:::::::::

consensus       KVEAYPAKKEAAVENAREALEQL---------------------------------
#oth            .......1123.11213121663332323222211111111111111111111111
VNG1287         :::::::::D:::::::D::AD-:::::::::::::::::::::::::::::::::
HQ1808A         :::::::::S:::K::D:::T:AASLLAANDSE:::::::::::::::::::::::
HVO_1249        :::::::::::::::::D::LGDE::::::::::::::::::::::::::::::::
Hbo0296         :::::::::D::::::::::L:ASELDAEDD:::::::::::::::::::::::::
Hut1218         :::::::T:DR:I:HV:::::T::::::::::::::::::::::::::::::::::
hla2382         ::::::::::::::::::T:GR:ADDSDDNGDDSDTSDDDTSDDDASGDDDTSDES
NP3528A         ::::::::R:R:I:T:ED:FHN:ASDD:::::::::::::::::::::::::::::
rrnAC1178       ::::::::R:K:::::::L::E::::::::::::::::::::::::::::::::::
Hmu1467         ::::::::R:T:I:::QD::SE::::::::::::::::::::::::::::::::::