[S] (-) COG1340 Uncharacterized archaeal coiled-coil protein 9 genomes BUD0285 9 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG0394 rrnAC1820 HVO_0880 Hbo0659 Hmu0783 Hut0362 hla0086 NP4058A HQ1530A

Pairwise sequence scores
Consensus score	2189	VNG0394	HQ1530A	HVO_0880	Hbo0659	hla0086	Hut0362	NP4058A	rrnAC1820	Hmu0783
1770	VNG0394	2201	1642	1657	1677	1678	1641	1695	1687	1681
1912	HQ1530A	1642	2245	1852	1933	1881	1733	1785	1701	1724
1865	HVO_0880	1657	1852	2249	1972	1858	1673	1771	1708	1691
1950	Hbo0659	1677	1933	1972	2253	1905	1696	1793	1702	1711
1984	hla0086	1678	1881	1858	1905	2253	1734	1832	1740	1788
1867	Hut0362	1641	1733	1673	1696	1734	2163	1825	1868	1874
1968	NP4058A	1695	1785	1771	1793	1832	1825	2173	1888	1863
1896	rrnAC1820	1687	1701	1708	1702	1740	1868	1888	2161	1910
1920	Hmu0783	1681	1724	1691	1711	1788	1874	1863	1910	2158

307 symbols
consensus       MVT---V----DVDSIDESDNVELTDDDLENKSKGQLIKLAGQLRDRRNELNQMASERAS
#oth            1223342334423232433312422123.221...1...3...1.....1...1..1...
VNG0394         :AEEETTIEVSTA:EL-------I:::E:Q:::::::::N:::F:::::::::L::S:::
HQ1530A         :::KNS:VETH::E:LK::::IS:::SK:D:G:::::::V:::::::::D::::::::::
HVO_0880        :::KQE:LSEF::QEL::AR:ID:P:EK::SG:::E::::::::::::::::::::::::
Hbo0659         :::QQD:LKEY::QKLSDA::::::::Q:DSG:::::::::::::::::D::::::::::
hla0086         :::KEE:IEQY:IEAM::A:::D:SE:::::G:::::::R::::::::::::::::::::
Hut0362         ---:::-::::MT:::E::K::SV::E:::T::::E:::::::::::::D::::::::::
NP4058A         ---:::-::::MAE::::T::::::E::::::::::::::::::::::::::::::::::
rrnAC1820       ---:::-::::MA::::::K::TV:EE::::::::E::::::::::::::::::::::::
Hmu0783         ---:::-::::M:::::Q:K:::::E:::::::::E::::::::::::::::::::::::

consensus       ERDDLNAKTREKVDEAQEHREKRDELNEQVQEHKEKRNELNAEANELFDKVEQLKEDLEL
#oth            6..1.............1...2..11.12.....33..1...2.....12.133.411..
VNG0394         ::::::::::::::::::::::::::::R::::::I::D:::D::::::E:::R::::::
HQ1530A         L::E:::::::::::::K::::::::::::::::D::::::::::::::Q::EM:AE:::
HVO_0880        K::::::::::::::::K:::::::M:S::::::QS::::::K::::::E:DEM:S::::
Hbo0659         K::::::::::::::::::::Q::S:::::::::N::::::::::::::::::M::::::
hla0086         N:::::::::::::::::::::::::::::::::D:::::::D::::::E::E::Q:M::
Hut0362         Q:::::::::::::::::::::::::::::::::::::::::::::::EQ::DK::EM::
NP4058A         ::::::::::::::::::::::::::::::::::::::::::K::::::::DD::A::::
rrnAC1820       A:::::::::::::::::::::::::::::::::DQ:::::::::::::::DN::N::::
Hmu0783         D::::::::::::::::::::E::::::K::::::S::D::::::::::::::::NEM::

consensus       DEGKSIEELKEEIEDLEFKQQTEVLSSEDERELIEKIEEKREKLAEKKEKLDQSGDLEEL
#oth            12.12211.12...2...1......12...2......15..12133122.1122311121
VNG0394         ::::DL:Q::::::E:::::::::::T:::::::::::G:::EYQDRE::::::::::G:
HQ1530A         ::::N::::ED:::Q:::R:::::::::::::::::::D:::Q:QQ::Q:VED::E:DS:
HVO_0880        :D::D:D:::::::Q:::R:::::::T:::::::::::N:::E:RQR:D:VEE:::::::
Hbo0659         :D::D:::::::::Q:::R:::::::T:::::::::::N:::E:RQ::D:VED::E::::
hla0086         GS::::::::::::::::R::::::DA::::::::::D::::::::::::V:DTSE:D::
Hut0362         :::::VDQ:ED:::::::::::::::::::Q:::::::Q:::::::R::::E:TD:ID:I
NP4058A         ::::::DQ:E::::::::::::::::::::::::::::::::::S:R::::::G:E::::
rrnAC1820       :::T:V:Q::::::::::::::::::::::K:::::::T:::::Q::Q:::::G::::::
Hmu0783         :::::::::ES::::::::::::::::::::::::::::::D:::S:::::::TE::DG:

consensus       KEEAEEVRSEASQHHQKVTELADKAQEHHNQMIEAYREADDIRDEADEMHELFVEAQEAA
#oth            211.111.1...1..1.......3..1...1.........1...1..12.13..1...1.
VNG0394         V::::S::A:::K::E:::::::::::::::::::::::::::::::::::D::::::::
HQ1530A         ::Q::::::::::::::::::::N:::::::::::::::::::::::A::::::::::T:
HVO_0880        I::::::::::::::::::::::D::::::::::::::::::::K:::::::::::::::
Hbo0659         I:::::::::::::::::::::::::::::::::::::::::::K::A::::::::::::
hla0086         V:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
Hut0362         :A::Q:I:::::K::::::::::E::::::E:::::::::E::::::::::K::::::::
NP4058A         ::::Q:::A:::::::::::::::::::::E:::::::::::::::::W:DK::::::::
rrnAC1820       ::::::::::::K::::::::::E::K:::E:::::::::E:::::::K::E::D:::::
Hmu0783         :::::::::::::::::::::::E::K:::E::::::::::::::::::::K::::::::

consensus       DQHHEDFVRVQKRLRELDKQEEEERRDERAEKREAAKEEAEEIYQKFKEGETLDTEDLMK
#oth            .3...1..1..........2..411336.2111.1111......12..1....1....1.
VNG0394         :A:::A::E:::::::::::::::EK:K::QEQ:E:R:::::::ER::::::::::::R:
HQ1530A         :E::::::::::::::::::::Q::E:::T:E::::::::::::::::::::::::::::
HVO_0880        :R:::::::::::::::::K::RQ:K:S:::E:::::A:::::::::::::::E::::::
Hbo0659         :R:::::::::::::::::::::::DA:::::::::::::::::::::::::::::::::
hla0086         :::::::::::::::::::E::K::K::::::::EE::::::::::::::::::::::::
Hut0362         :::::::::::::::::::E::::E:SR:E::Q:::R::::::::E::D:::::::::::
NP4058A         :R:::::::::::::::::E:::::EED:::E::::::::::::::::::::::::::::
rrnAC1820       :::::::::::::::::::K:::QE:SQ:E::Q:::R:::::::::::::::::::::::
Hmu0783         :::::::::::::::::::K::A:E:SA:E::Q:::R:::::::::::::::::::::::

consensus       LQKTGLL
#oth            ...2.2.
VNG0394         :::S:H:
HQ1530A         :::::::
HVO_0880        :::S:::
Hbo0659         :::::::
hla0086         :::::::
Hut0362         :::::::
NP4058A         :::A:K:
rrnAC1820       :::A:K:
Hmu0783         :::A:K: