[J] (SIK1) COG1498 Protein implicated in ribosomal biogenesis, Nop56p homolog 9 genomes BUD0328 9 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG1174 rrnAC0864 HVO_1670 Hbo3167 Hmu1626 Hut1101 hla2287 NP2064A HQ2568A

Pairwise sequence scores
Consensus score	2109	HQ2568A	VNG1174	NP2064A	Hut1101	rrnAC0864	Hmu1626	HVO_1670	Hbo3167	hla2287
1326	HQ2568A	2136	1070	1144	1112	1166	1163	1193	1266	1116
1476	VNG1174	1070	2091	1161	1224	1217	1262	1266	1336	1232
1497	NP2064A	1144	1161	2083	1266	1321	1338	1171	1283	1203
1562	Hut1101	1112	1224	1266	2080	1373	1454	1228	1254	1305
1610	rrnAC0864	1166	1217	1321	1373	2093	1531	1325	1276	1305
1660	Hmu1626	1163	1262	1338	1454	1531	2089	1348	1328	1292
1582	HVO_1670	1193	1266	1171	1228	1325	1348	2095	1446	1342
1641	Hbo3167	1266	1336	1283	1254	1276	1328	1446	2129	1413
1599	hla2287	1116	1232	1203	1305	1305	1292	1342	1413	2138

295 symbols
consensus       -MTD-------G-WFADIDPDDDEAAAAAIRDGEADEPADWPALAVESGFADDEDDYYDR
#oth            1224124433411..315433.5332432144.4.33152..53..1314121433..34
HQ2568A         ::SK:EQSDNPA:::S::::::ID:::T::TN:A:ED:QN::TQ::::EIVE:TTT::QL
VNG1174         MT:H:::::::::::::TAVR:AD:::D:V:N:H::A:EN:::A:::D:VV::A:E::::
NP2064A         :::::ERAVED::::::VP:G:V::::::::::S:ATVGE::S::::::V:A::::::EQ
Hut1101         MN:E::::::::A::H:VSAG::ST:Q:R:::::::D:::::G::::T:Y:::V:A:::A
rrnAC0864       ::SN::::::::::::GL:::::A::VEQ:EA:R::T:E:::QQ:::A::::::AA::::
Hmu1626         ::::::::::::::::GL::::::::V::::E:S:::::E::R:::DA:::::T::::::
HVO_1670        :::::::::::A::::GA::::P:PG:TRV:T:S:SA:T::::E::DA:::A::S:::AK
Hbo3167         ::N:GTAPTGT::::E::A:::A:S:SE::A:::::::R::::::::::H::S::E:::Q
hla2287         ::::::TDDNA:::::G----:ES:LR:R:V:::::::R:::G:::::::::SR::::::

consensus       LHEATLAATRAAVRERERADDQQLVHAVRAMDDCERTANELAERVAEWAGSRYDDAGSGV
#oth            .133251.134..413.31..3..4.111212.4112...11..22..1221533335.2
HQ2568A         ::D:AIT::QN::ESY:AS::R::R:CLT::::V:::::::T::LT::G:::I::SDT::
VNG1174         :RD::R:::::::::::::::::::::::TIG:LSDA:::V:::AV:::RTLF:GVDD:I
NP2064A         ::::AV:::::::H:A:T::::::I::::::::T::V::::::::T::::D:::AD:T::
Hut1101         ::SI:T::AET:::::::::::::K:::::::::::::::::::::::::T:LA::::::
rrnAC0864       :::V:M:::S:::A:Q:G:::::::::::::A::::::::::::::::G:::HG:S::::
Hmu1626         :RA::M::AEQ::Q:::G:::R:::::::S:A::::::::::::::::GE::SA::::::
HVO_1670        :RS:::::ASE::A:::::::V::A::::::::A:::::::::::V::::TL:EEVPR:L
Hbo3167         :R::::T::::::::::::::K:::::::::::A::::::::::L:::::TL:::::V:I
hla2287         :::TSV::::E:::::::::::::::::::::::::::::::::A::::::LF:::EP:I

consensus       EGARDLADREPSDPAEERLVSLAERVVDLADERDDLRAFIERTAPAVAPNLAALAGPVLA
#oth            4211321453363452532411141342.32.114225311351133....231..11..
HQ2568A         DTV:E:::IT::T:V:T::T:::TQ:LM:YE::::::TY::TQ:AT:::::T:M::::::
VNG1174         A::::V:G:SANS:T:::AIA:C::AT:::::::RAQG:V:TH::T:::::SM:::::::
NP2064A         :Y:AS:::ADDL:--DPQ:R:::::IR:::A:A::::SHV::VT:EI:::::R:::::::
Hut1101         GY::E:VTG:T::R:DAD:::::Q:::A:D::AAE::RT::T:::D:::::S::::::::
rrnAC0864       :Y::S:::::DE:EGDRA:R::::QTAA::::A:SI::Y::::::::::::SM:::::::
Hmu1626         :Y::E::AS::::::G::VQ:::Q:::::DE:A:R:::Y:D::::E::::::::::::::
HVO_1670        N:V::I:V:::KTA::::V::Y:T:A:::L:::::::::::ER::TT:::::EM::::::
Hbo3167         ::::::::KD:QT:V:D:V::Y:R::A::::::::::::V:SR:::L:::::EM::::::
hla2287         ::::AV:::::TGEL:R:A::::A::::::A:::A:AET:D:I:::::::::EM::AE::

consensus       ARLIALAGGLEPLAKKPSGTVQVLGAEDALFAHLRGRAPSPKHGVIYTHEYVRGTHPEDR
#oth            1..12.....25..13.1..2......1......4.2121....2.11..1121.3123.
HQ2568A         T:::E:::::KS::RQ:A::I:::::::::::::E:::SA::::A:F::::::::::AN:
VNG1174         ::::::::::DD:::L::::::::::::::::::::H::::::::::::::::::::DQ:
NP2064A         ::::::::::KQ::R::A:::::::::E::::::::::::::::::::::AIQ::A:AH:
Hut1101         ::::S:::::::::::::::::::::::::::::Q:S:::::::I:::::::S::V:AQ:
rrnAC0864       ::::S::::::A::::::::::::::::::::::K:S:::::::::F::::::::RR:::
Hmu1626         :::VS::::::S::::::::L:::::::::::::::S:::::::I:F:::A::::::DH:
HVO_1670        ::::::::::::::::::::::::::::::::::K:::T:::::::F::::::::R::::
Hbo3167         :::::::::::R:::M::::::::::::::::::E::GS::::::::V::::::::::H:
hla2287         ::::::::::::::::::::L:::::::::::::S:::::::::I::::::::N:R::::

consensus       GSAARALAGKLTIAARIDHYSGDRRPDLHAELDDRIETIRARA--G------DDE
#oth            ...1..1....21...1.....242331331.32.112.11.4422111111331
HQ2568A         ::::::F::::A::::::::::THKQSI:D::T:::::::::NKE-:::::::TA
VNG1174         ::::::::::::::::V:::::::::::E::::A:M:R::::-::-::::::ET:
NP2064A         ::::::::::::::::::::::E:N:E:E:D:R::::R:Q::-::-:::::::A:
Hut1101         ::::::::::::::::::::::::::E:D:::::::::::S:-:::::::::EGA
rrnAC0864       ::::::F::::S::::::::::::::::QV:::E:::R:Q:::EE::::::::::
Hmu1626         :::::::::::::::::::::::L::::Q::::E:::A:QS:TG:::::::::G:
HVO_1670        :::::::::::A::::V::::::Y::::::::A::M:::::::DE:::::::G::
Hbo3167         ::::::F::::A::::::::::EFKSEI:E::AE:M::::::E::-::::::VA:
hla2287         :::S::::::::L:::V:::::E::ET::E::RE:MA::::::KDESDAAAEG:A