9 genomes BUD0341 9 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG1246 rrnAC0805 HVO_1324 Hbo0223 Hmu1517 Hut0681 hla1368 NP4180A HQ2760A

Pairwise sequence scores
Consensus score	1057	Hut0681	NP4180A	hla1368	rrnAC0805	Hmu1517	VNG1246	HQ2760A	HVO_1324	Hbo0223
677	Hut0681	1077	645	531	660	637	607	579	539	617
706	NP4180A	645	1086	570	634	661	654	575	603	642
745	hla1368	531	570	1600	606	633	602	678	669	691
813	rrnAC0805	660	634	606	1054	744	673	655	603	713
860	Hmu1517	637	661	633	744	1051	739	713	662	746
781	VNG1246	607	654	602	673	739	1072	684	689	748
813	HQ2760A	579	575	678	655	713	684	1142	754	827
808	HVO_1324	539	603	669	603	662	689	754	1076	848
888	Hbo0223	617	642	691	713	746	748	827	848	1076

209 symbols
consensus       ---------------------------------------------------------MSA
#oth            111111111111111111111111111111111111111111111111111111111133
Hut0681         :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::I
NP4180A         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::TS
hla1368         MNYPPGGGALKVPSPILATEAGRRRGLWRGRRRRPRRLRRPPSAPLLRRAHRTTCMSAPS
rrnAC0805       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::N
Hmu1517         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
VNG1246         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
HQ2760A         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
HVO_1324        ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::R:
Hbo0223         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::

consensus       RNDIAPETLGVELTDEGVVVEYLDGRETFYHGVPETVEGSVTTAPGKEVHVLVTDPTETE
#oth            .2.11.312212.523..41..3.1.322.2.1.5432123524.1.21.1.1.123..3
Hut0681         :T:VP:::I:::::::::::::A:::::::::I:NRA::A:R:M:::Q:::::::ES::A
NP4180A         :S:::::::T:S:ES:::E:::::::SV:::::::KKA:A:HCP:::D::::::A:D::Q
hla1368         :S:VP:TSI:ID:RE::::I::::::T:L:R:::DA::::::AG::::T:::::::::::
rrnAC0805       :S::::D:VS::::ED::::::::::QA::::::T:::::IQ:::::DT:::I::K:::S
Hmu1517         :::V:::::S::::ED::::::T::::V:::::::R::D::VA::A::::::::::N:::
VNG1246         ::::::S::::::AE:::Y:::T::::A::N::::PI::TLH:N:::D::::::::::::
HQ2760A         ::::::::V::::L:H::A:::I:::Q:L:R:::K::TD:F::P:::QT:I:::::::::
HVO_1324        ::::::S::::::H:Y::E:::::N:T:V:R:::QA:T:TLA::::::::::::::::::
Hbo0223         :::VP:S::::::L:H::Q:::T:::T:L::::::::T:TL:::::::T:::::::::::

consensus       GVLVYVNDLNTHDDILESTGVGRVILDDGEEEELFPGVTVRR-TGMRTEVEADPEVARGR
#oth            .113.1..2412121..21....23226115321....52643434144131.21323..
Hut0681         ::::::::RI:EAE::::::::::V:EP::KTTV::::RAAN:DAR:IV::::FDAVD::
NP4180A         ::M:::::R::::::::::::::::IEG::TAS:::::AAES:::Y:V::S::FD::D::
hla1368         ::MT::::Y::D:E:::DS::::::VE:::RD:V::::I:G::::Q:N::I::::I:G::
rrnAC0805       :I:::::::R:::::::E:::::::::::::D:::::::::D:NQ:::A::V:YD:TN::
Hmu1517         :::L:::::::::::::E:::::IM::T::Q::V:::::ITD::S::V:::::::T::::
VNG1246         :::::::::K:::E:::::::::LL::P::R:::::::::QA:D:YAIDID::::T::::
HQ2760A         :::L:I:::K:::NV:::S:::::V:EQ:SS:TV::::::S:LN::::TI:::::T::::
HVO_1324        ::MM:::::TS::EV:::S:::::::GED:::::::::L:::VP:H:F:I::::::::::
Hbo0223         ::MM:::::K:::::::::::::::::A::::::::::S:::TE:::::I::::::::::

consensus       VFVFVEDEWGERSYEIVEE----------
#oth            ....2..322.611.2.656334222121
Hut0681         ::::E:::M::::F:L:P:GRGE::::::
NP4180A         ::::A::QM::F:::L:P:SEVA::::::
hla1368         :::::::G:T:G::::::APEDGLDAHR:
rrnAC0805       ::::E:::L:::::::::G::::::::::
Hmu1517         ::::::::M::::::::SSE:::::::::
VNG1246         ::::A:::LS:YA::::GPA:::::::::
HQ2760A         :::::::D:S:Q:::F:QQTTDSAESHEE
HVO_1324        :::::::D:::D:::F:A:::::::::::
Hbo0223         ::::E::D:::S:::F:T:::::::::::