[J] (eRF1) COG1503 Peptide chain release factor 1 (eRF1) 9 genomes BUD0346 9 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG1842 rrnAC3452 HVO_2640 Hbo2202 Hmu2495 Hut0663 hla1654 NP2484A HQ3027A

Pairwise sequence scores
Consensus score	2220	hla1654	VNG1842	NP2484A	HQ3027A	HVO_2640	Hbo2202	rrnAC3452	Hmu2495	Hut0663
1410	hla1654	2282	1028	1167	988	1122	1113	1077	1202	1154
1364	VNG1842	1028	3365	1234	966	1030	1016	1036	1189	1120
1391	NP2484A	1167	1234	2182	1028	1039	1104	1112	1218	1125
1299	HQ3027A	988	966	1028	2260	1052	1234	1056	1013	986
1492	HVO_2640	1122	1030	1039	1052	2315	1381	1127	1212	1161
1486	Hbo2202	1113	1016	1104	1234	1381	2228	1139	1175	1178
1554	rrnAC3452	1077	1036	1112	1056	1127	1139	2373	1467	1345
1684	Hmu2495	1202	1189	1218	1013	1212	1175	1467	2252	1385
1560	Hut0663	1154	1120	1125	986	1161	1178	1345	1385	2253

457 symbols
consensus       ------------------------------------------------------------
#oth            111111111111111111111111111111111111111111111111111111111111
hla1654         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
VNG1842         MHLSVSVTNIHMHVRGVLKRLLPRTVVRRTRGHRPGRHQPVAPPAGQRTAVHHRGRRLPD
NP2484A         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
HQ3027A         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
HVO_2640        ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
Hbo2202         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
rrnAC3452       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
Hmu2495         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
Hut0663         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::

consensus       ------------------------------------------------------------
#oth            111111111111111111111111111111111111111111111111111111111111
hla1654         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
VNG1842         RPPARDETRGRPPRGRRPGGRPTADACSACRSPRRPERRQPADALGGPARETRPRRPPAR
NP2484A         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
HQ3027A         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
HVO_2640        ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
Hbo2202         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
rrnAC3452       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
Hmu2495         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
Hut0663         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::

consensus       --------------------MLDELLGRAELKARIEELEEEKRHLERQLDAEEERRADAV
#oth            12212222222222222221.11211..24.121131.131323.331121.42..2212
hla1654         :::::::::::::::::::::I:R:::::G::E::::::::::::::RAE:::Q::S:::
VNG1842         HRRRLTRGATPILAAPRDHS:::D::::T::::::DD::A:ADS:QQ:::::AD::SE:A
NP2484A         :::::::::::::::::::::::DI:::T:::EQ:A:::D:RDR:AA::E::S:::::::
HQ3027A         :::::::::::::::::::::::::::::::::Q:VD:KQ::H::::::A::::::T:::
HVO_2640        :::::::::::::::::::::::::::::::::::A:::D:RDA:AGR:EG:S::::E:A
Hbo2202         :::::::::::::::::::::::::::::K::::::::::::H::::RAE:::::::A::
rrnAC3452       :MQRRFGKSLLSPSPSAIQS:::R:::::S::E:VA::::ANH:::::::::K::::::A
Hmu2495         ::::::::::::::::::::::E::F::RS::G::::::::::::Q::::::QD::::::
Hut0663         :::::::::::::::::::::::::::::R:RE::::::D:N:::T::::::SD::::VE

consensus       RERQAAEARVNRLEDRIEELEDRVERLSGD--EAE-LEFRRTEDLRGARLDEVLDRLESV
#oth            431.3.1212.2.221133.1211313435112541542.44321525.1552.313212
hla1654         AD::R::E:::E::H:::S::E:LD:TE:A:::ES:V::::VS::HDP::ADA:G:FRA:
VNG1842         :K:::::R:A:E::TK::::Q::LD:TDSG::D:A:P:::DRIA:T:R:R:R::AL:::L
NP2484A         S:K:::QE:I:::::::AD::GKLQQ-ESE::S:::IG:::K:T:H:K:R:A::S:V::F
HQ3027A         ::::E::RE::Q:Q::::G::E::::::ESQT:RDE:SV:T:Q:I::::RKNI:::IR::
HVO_2640        :A::E:::E::::::::T::::::::::::::DDS::D::G::::::D::R:::S::D:L
Hbo2202         KD::E:::E::::::::T::::::S::G::::DEAE:DY:G::::F:E:R::I:S::::F
rrnAC3452       T:::R:::E:::::::VA::Q::::::QDE:::G::ST::AE:T:SR:::S:::::::::
Hmu2495         SD::D::E::::::::VT::::::Q:QQ:K::SGR:G::::E:T:S:E:::D:::::D::
Hut0663         T::::::R:A:::D::VQ:::::::::::S:::Q:::SV::R:T:C:D::TTI:::::::

consensus       ETG-PEGALTAYVADD--LPDAVRDAFGDRAPLVRRAAPCLVVTDDAGLVSVALSPPAPP
#oth            22311..211.4.523343.443333212123..312..12344.12142222144155.
hla1654         :SDD:::L:::F:P::DAV:SS:AEW::::TR:::::::AV:IA::T:A::A::T::IE:
VNG1842         DA:::::V::::::::::P:AQL:::L:::::::A::::::::H:RD:I::T::R::N::
NP2484A         :AK::::V:::::D::::V::ELAEQL:::T:::::::::::CV::::VLAT::R::VA:
HQ3027A         :::::::::::M:TET::V:NEI:RLLDE:SA::Q:L:::::CI::::MIA::IELT:::
HVO_2640        S:D:E::::::A:S::RS::S:AES:::G:::::::::::VAL:::::V::::::::RQ:
Hbo2202         S:::::::FS:V:G::::I::E:A::::::SA:::::::::CL:::::::::::DA:TL:
rrnAC3452       ::E::::VF::::DAERS::GP:::::::::S::AS:::::A:::::::L:AC::V::::
Hmu2495         :::::::::::::::EHD::A:::::V::D:::::::::::L:V::::::GTT::T:VS:
Hut0663         ::D::::::S:F:G:A:P:::::S::::::SS::S:V:::FAF::::R:L::::D::IE:

consensus       EPFVEWADGFRLERSWFEPTGRHAVALVRSDLFALGVYEGRERTAFHGFTSDVKSAHSKG
#oth            42.43.533353134125.223432.1..2.2..2.2.314334524312121243....
hla1654         A::DR:S:R:::DE:::R::::F:F::::::T::::::::D::V::E:::::::E:::::
VNG1842         :::C::GQTA:I::D:LA::::Y:L:V::A::::V:::RDGD:RS:D::::N:::D::::
NP2484A         :::::::GRPTV:::::V::::::L:V::::I::V:::::D::VDIRTV::N:::D::::
HQ3027A         T:::::GTT::I:PQ:VA:AEPVT::V::::I::::::D:STL:HVTDV:T::MD:::::
HVO_2640        DD:DR:S:::D:DPV::H::ETT::::::G::::::R::DGDLEFVE::E::::::::::
Hbo2202         :E:AT:N:E::::::::T:EEPVR::::::::::V:::D:ESV:LVDEVE:::MN:::::
rrnAC3452       S::TG:::TVQ:::::::::DE:V::::::::::M:E:D:::Q::::::D:EL::Q::::
Hmu2495         :::A::R:::AIDHT::::::EY:::::::::::::E::::D:::::::D:EL::Q::::
Hut0663         D:::T:D::AVFD::H:::::EFTL:::::::::M:E:H::::I:::::D::LGRN::::

consensus       GFSQARFERLRDEQIDSHLDRCHAAL----------EERDA----D--RLYVVGERTVLG
#oth            ....2....2.13.125.223164.12221211132524331111211333.1.242113
hla1654         ::::G::::R:EG:::E::KKAT:::::::::::::ADL::NAPI::::TI:::::S:::
VNG1842         :::::::::::::::QA::EE:QR::::::::::::ADI:::::::::::F:::QD:L:D
NP2484A         ::::S::::I:::::QK:IKKAS:::::::::::::DDI::::::E:::R::::D:RLI:
HQ3027A         :::::::::R::Q::ED::EHA:E:IETHLT:::ENSQIQT::::S::EVV:L::K::::
HVO_2640        ::::G::::I:EG:::D:I::::E::DEFLGGGSGAG::AG:::::DAD:V:L:::::::
Hbo2202         :::::::::R::::VEN::::AKD::::::::::AAN:NA::::::::G:V:L:::::::
rrnAC3452       ::::S:::::::Q:::::::::R::I::::::::::::VSP::::::::::::::GS:IH
Hmu2495         ::::::::::::A:::::V:::L::I:::::::::::::::::::E::::::::::SL:P
Hut0663         :::::::::::::::::::E::LV:::::::::::::::ST::::::::::::::Q:::D

consensus       EFRDRADATATVDATGDPEAALDDAVREFWTTRLRAL
#oth            3143513434311.1.2.45..42.3421.3322362
hla1654         :V:EH::I:DVS::::K:RN:::::FHD::M::I::I
VNG1842         A:D--:::::A:::::::AD::A::HTD:::LP:SL:
NP2484A         ::D--:::::A:N:::K:KP::E:::::::SV::YG:
HQ3027A         A:S:L:GRRE::::::E:KS::E:::D::::I:VST:
HVO_2640        ::::::AL::::::S::::T::TE:S::::::::YR:
Hbo2202         D::AM::HV:::::S::::D::RA::::::::::YC:
rrnAC3452       ::E:LST:MKP:::::E:D::::::::SL::V:::VP
Hmu2495         K:A::::::QP:::::E:::::A:::H:::RV:::V:
Hut0663         A:EEA::::::::::::::P:::::FYD::::T:W:I