[R] (-) COG2102 Predicted ATPases of PP-loop superfamily 9 genomes BUD0375 9 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG0391 rrnAC0632 HVO_1077 Hbo0582 Hmu1037 Hut0365 hla2515 NP0382A HQ1669A

Pairwise sequence scores
Consensus score	1800	HQ1669A	VNG0391	hla2515	HVO_1077	Hbo0582	Hut0365	NP0382A	rrnAC0632	Hmu1037
1310	HQ1669A	1886	1166	1140	1253	1250	1193	1191	1173	1250
1413	VNG0391	1166	1846	1220	1250	1261	1251	1195	1273	1239
1355	hla2515	1140	1220	1821	1274	1343	1204	1151	1239	1248
1473	HVO_1077	1253	1250	1274	1816	1423	1248	1263	1344	1391
1462	Hbo0582	1250	1261	1343	1423	1814	1211	1226	1285	1327
1445	Hut0365	1193	1251	1204	1248	1211	1841	1319	1397	1301
1408	NP0382A	1191	1195	1151	1263	1226	1319	1805	1347	1277
1502	rrnAC0632	1173	1273	1239	1344	1285	1397	1347	1826	1400
1505	Hmu1037	1250	1239	1248	1391	1327	1301	1277	1400	1830

255 symbols
consensus       -----------MDGAWVSLFSGGKDSSWALYRALEDGLDVERLVTVHPEGDSYMYHVPAT
#oth            111111122334345..1........1..1.....4.32.41.1....33..1...2.1.
HQ1669A         MNISADNQPQQTSNH::::::::::::::::::::::R::TH:L::::SA::::::::E:
VNG0391         ::::::::::MT::Q::G:::::::::::::::::A::::G::::::::S::::::::::
hla2515         ::::::::::::TDD::::::::::::::::::::E::::S::L::::A:::::::T:::
HVO_1077        ::::::::::::TSE::::::::::::::::::::E::N:T::L::::SD::::::::::
Hbo0582         :::::::::MTES:D::G:::::::::::V:::::A::::T::L::::GD::::::::::
Hut0365         :::::::MTDTA:S::::::::::::::::::::::::P:::::::::A:::::::::::
NP0382A         :::::::::::-MKP::::::::::::::::::::::KP:::::::::::::F:::::::
rrnAC0632       ::::::::::MT:::::::::::::::::::::::R:HP:::::::::::::::::::::
Hmu1037         ::::::::::::TD::::::::::::A::::::::S:R::Q:::::::SD::::::I:::

consensus       RLAALAAESIGIELVEVEPDDF--GAADAADSGEQGDAELEPLEAALEALAAELDGGLAG
#oth            5..5...2.41.312215.22111315416.1141..2....1.311532232333223.
HQ1669A         K::Q:::K:A::::I:IN::E:::D:SN:V:A:T:::R::::::N:V:::DKT:T::IT:
VNG0391         :::E::::::::PV:N:T::A:::ET::V::A:A:::T::::::D:VTDV:DT::D::::
hla2515         E::::::::V::D::::S:A::::::D:VD:A::::::::::M::::REI::GD:VD:::
HVO_1077        D::::::::T:::::::H:G:L::E:TA:::::A:::::::::::::SD:Q::M:--:::
Hbo0582         H::::::::L::::I::T:::L:::::E:T::S::::::::::::::::::::I:--:::
Hut0365         D::R::::::D:P:L:I:::::::::G:VR:A:V:::R::::::G::AE:DD:::::V::
NP0382A         E::S::::::::P::N:R::::DD::TA:E::SQR::R:::::::E:S:::D::-::ID:
rrnAC0632       :::R::::::::Q:::I:::::::E:D:VP:::::::::::::::::HE:DT:::::IS:
Hmu1037         S::T:::D:::::::D:::::L::A:ES:V:::Q::::::::::::::T:D:::P::V::

consensus       VTAGAVESEFQTSRIEGMCDRLDAELFAPLWQEDPRELAEAMLAAGFEIRIIQVAAYGLD
#oth            12...1..21..3.222121..22211.....23.23.112.23.....2.12.1.3...
HQ1669A         ::::::::::::D::R:::N:::I::::::::R::IT:::N:I::::::T::::::R:::
VNG0391         :I::::::D:::::M:::::::GC::Y:::::QP:::::D:::T::::::::::::::::
hla2515         :::::::::::::::Q::::::GID::::::::S:VA:::::FE:::::::V::::::::
HVO_1077        :::::I::::::D::QA::::::ID::::::::N::::GD:::E:::::T::::::H:::
Hbo0582         :::::::::Y::N::Q::::::EID:::::::::::::G:::ID:::::Q::::::H:::
Hut0365         LV:::::::::::::::LS:::::::::::::R::VD:::S::D:::::::VS:S:A:::
NP0382A         ::::::::SY::D:L::L::::::::::::::QN::::::::F::::::T:VS:S:R:::
rrnAC0632       :::::::::Y::T:::S:A:::E:NV:::::::N::D::D:::D:::::Q::R:::::::
Hmu1037         :::::::::Y:::::RA:::::::::::::::::::A::D::::::::::::::::::::

consensus       ESWLGRTLDADALAELAALNDEYGVHILGEGGEFETLVTDGPHMDRPIELEYETEWEGTR
#oth            21....11.421.32.54.1222...3.........2.111..1111.222.3.412.31
HQ1669A         S::::::::TET:S::IT:::RH:::V:::::::::F::N:::LS:::::::T:I:::::
VNG0391         K:::::R::R::::A:::::::::::M:::::::::::::A:::::::R:D:::V:A:D:
hla2515         ::::::RY::::::::VD:RE:C:::P:::::::::Y:V:::::::R:DM::D:V:::D:
HVO_1077        :::::::::::T:D:::::::R:::::::::::::::::::::::::::::::::::::H
Hbo0582         :::::::::H:::E::VE::EQ::::P:::::::::F:::::::SN::::::::V:::::
Hut0365         :T::::R:::::::D:RE::A:::::V:::::::::::::::::::::::D:V:D:D:::
NP0382A         ::::::::::E:::::ER::::::::V:::::::::::::A:::::R:::::::TFD:L:
rrnAC0632       :::::::::::::D::E:::::::::::::::::::::::::::::R::I::::::D:S:
Hmu1037         :::::::::ET::D::TT::E:::::::::::::::::::::::::::R:S:D:::::D:

consensus       GHIRITDAWLG----
#oth            .523122.4.34221
HQ1669A         :Y:DV:N:T:R::::
VNG0391         :::E::E:C::P:::
hla2515         ::VE:R::R:E::::
HVO_1077        :RL:::::F::EESG
Hbo0582         ::LE::::R::E:::
Hut0365         :S:::E:::::::::
NP0382A         :SLQ::::::AA:::
rrnAC0632       :TVQ:E::::A::::
Hmu1037         :GV::E:::::DGE: