[H] (BtuR) COG2109 ATP:corrinoid adenosyltransferase 9 genomes BUD0405 9 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG1574 rrnAC1936 HVO_A0488 Hbo0925 Hmu0513 Hut0158 hla0297 NP4974A HQ1405A

Pairwise sequence scores
Consensus score	1750	HQ1405A	Hut0158	NP4974A	HVO_A0488	hla0297	VNG1574	Hbo0925	rrnAC1936	Hmu0513
1269	HQ1405A	1864	966	1080	1156	1152	1004	1136	1066	1067
1228	Hut0158	966	1872	996	1052	1113	1058	1018	1096	1109
1314	NP4974A	1080	996	1715	1214	1183	1026	1143	1093	1087
1439	HVO_A0488	1156	1052	1214	1835	1240	1033	1225	1120	1121
1380	hla0297	1152	1113	1183	1240	1961	1053	1235	1157	1169
1244	VNG1574	1004	1058	1026	1033	1053	1730	1000	1189	1148
1332	Hbo0925	1136	1018	1143	1225	1235	1000	1761	1088	1124
1324	rrnAC1936	1066	1096	1093	1120	1157	1189	1088	1659	1303
1321	Hmu0513	1067	1109	1087	1121	1169	1148	1124	1303	1658

258 symbols
consensus       -MTDAPD-D-ETADE---------------------TPGGGARPAAEA------IEPAAP
#oth            1445533544345541111111112223334442342233285.3344111111.4121.
HQ1405A         MIGPLNYVMTDE:N::::::::::SSTINPKKTRQQ:::::E:::::T:::::::T:T::
Hut0158         :::RK:AD:S:A:TS::::::::::::::EREAAST:DE::DG:ET::VPDVEV:A::::
NP4974A         ::::R:-:-:-----::::::::::::::::::::::::R:RT:T:Q::::::::D::::
HVO_A0488       :::::::GTP::G::::::::::::::TTPDSVRAN:::R:V::E:A:::::::::::::
hla0297         MT::NN:T:ST:D:DADAPTDGEPTESDESSDPAAR:::::SA:EP:P::::::::::::
VNG1574         :-MT:T:D:TT:::::::::::::::::::::::::QDADTM:::E--:::::::T:T::
Hbo0925         MSNER::SPE::RQH::::::::::::::::::::::::::IS:::TD::::::::::::
rrnAC1936       :------:-:-----:::::::::::::::::::::MSDNT:G:T::P:::::::S:SV:
Hmu0513         :------:-:-MSED::::::::::::::::::::::D::---:R::P:::::::TAS::

consensus       DEFGLVQVWWGDGKGKTTAALGMAFRAAGHGYRVHLLQFMKGGADSVEDVRGEYNAIAAV
#oth            22..11.1...1.......11..13..1...1.1.21.11...131.131....11.312
HQ1405A         E:::R::::::S:::::::::::::::V:::F:::M::::::::::::GA::::::::::
Hut0158         :A:::::A:::::::::::::::GL::::::::::V:::::::TP:::G::::::::EH:
NP4974A         :::::T:::::::::::::T:::::::::::F:::V:::::::::::A:::::::::T::
HVO_A0488       :D::::::::::::::::::M::G:::::::::::M:::L::::::::A::::::::::M
hla0297         E::::::A::::::::::::M::G:::::::::::M::::::::::::G::::::::::M
VNG1574         A:::::::::::::::::::::::M::::::F:T:VV:L::::TGT::::::::A::D::
Hbo0925         E::::::A:::::::::::::::::::::::::::::::L::::::::S::::::V:::L
rrnAC1936       E:::::::::::::::::::::::T::V:::::::::::::::TST:::::::::::::L
Hmu0513         :D:::::A::::::::::::::::M::::::::::::::::::TS::::::::::::::L

consensus       PGISYENAGHYGWHGFLDGSDDDEHAARARAALDRARELVDAAADADLSAPLDLDGDPED
#oth            .1212..2..1..2134.114121.2.3161124.142123135321234.323124121
HQ1405A         :::::::T:::::::L:::::::::H:K:KG:MR:T:A:L:GIS::S:DT:I::S:::::
Hut0158         ::YTI::T::V:::::M:DTA::::::::::::E:::AI:::TGER:PTT:FA:::A:T:
NP4974A         :::::::L::::::AMN::TEERD:::E:E:G::::H:::A::D::::TS:F:P:S::D:
HVO_A0488       ::::F::L:::::A:MA:::::ED:E:QVA:G:N:::::::::::::::K::::::P:::
hla0297         ::F::::::::::::L::::G::::E:K:S::FE::ED::AG::::::A::IP:::::D:
VNG1574         :::T::::::::::::H:::S::::::::NGG:A::Q:I:::STGV:GAV:::A:--:TE
Hbo0925         :T:::::T:::::K:RM::::::::::K:Q::F::TK:::A::GE:::T:::PS::NA::
rrnAC1936       ::F:::::::::::::::::E::::E:::KG:::::Q:::Q:S::::::T:R:A::P::E
Hmu0513         ::F:::::::::::::::::::::::::::G::A::E::IE::IV:::::::A:::P:::

consensus       GVHMLVLDEVLYAANRGLVDPADVLALIESKPENLELVLTGGHEEPTYLTDAADLVTNVR
#oth            .112.12..2...1322.22322125.2261.14..2..1.1.42.4116271..212.3
HQ1405A         :::L:I:::::::VEQE:ITQD:::S:::Q::D::::::::S:T:::::F:DV::I::::
Hut0158         :::::I::::::::::::I::::L:D::AV::DG::F:::::::H:A::EGE:::LSH:E
NP4974A         ::::::F::I::::D:E::::EA:VR:V:E:::::::::S:S:SR:E::IES::::::::
HVO_A0488       :::F:II::L:::VAM::L:E::::D:V:R:::S:::::::S:D:::::S::::::::::
hla0297         :::::I::::::::D::::::EE:V::A:::::T:::::::S:G::D::DGV:::I::::
VNG1574         :::L:::::::::::::::::E::V:::DT::DD::V::::::T:::FV:ER:::::E::
Hbo0925         :::::::::I:::VEM::L:ADE::E:V:::::::::::::::::::F:L::::::SE::
rrnAC1936       ::N:::::::::::::::::::::IG:::A::DD::::::::::R:KF:::H:::I:E:S
Hmu0513         :L:::::::I::::::D:LA::::IE::::A::D::::::::::R:AF::EY:::::::A

consensus       KEKHPIDAGQRARKGTEY
#oth            .33.1312.32..2...1
HQ1405A         :Q::LF:D:I::::::::
Hut0158         :QA::LE:::P:::::::
NP4974A         :::::::D:::::M::::
HVO_A0488       ::::::::::::::::::
hla0297         :DA::F:::H:::R::::
VNG1574         :QR::MEN::G:::::::
Hbo0925         :VN::F:D:T::::::::
rrnAC1936       ::::::::::G::::::F
Hmu0513         ::R::L:D::G::::::F