[K] (RPB7) COG1095 DNA-directed RNA polymerase, subunit E' 9 genomes BUD0407 9 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG2053 rrnAC2829 HVO_1899 Hbo1777 Hmu3134 Hut2927 hla0881 NP5080A HQ1337A

Pairwise sequence scores
Consensus score	1433	hla0881	VNG2053	NP5080A	Hut2927	rrnAC2829	Hmu3134	HVO_1899	Hbo1777	HQ1337A
1196	hla0881	1443	1056	1146	1097	1102	1093	1173	1158	1117
1215	VNG2053	1056	1419	1202	1143	1171	1176	1165	1176	1127
1333	NP5080A	1146	1202	1421	1261	1283	1265	1197	1210	1184
1302	Hut2927	1097	1143	1261	1413	1285	1244	1148	1185	1160
1313	rrnAC2829	1102	1171	1283	1285	1429	1302	1150	1165	1154
1308	Hmu3134	1093	1176	1265	1244	1302	1429	1159	1155	1179
1247	HVO_1899	1173	1165	1197	1148	1150	1159	1427	1271	1205
1272	Hbo1777	1158	1176	1210	1185	1165	1155	1271	1434	1308
1267	HQ1337A	1117	1127	1184	1160	1154	1179	1205	1308	1441

194 symbols
consensus       MYKRVRLKDTVEVPPRHLADVTPELVKRLLQDKLEGRMDEDVGSVVSVIEVHDIGEGAVL
#oth            ....11.2..1....22.12.2131..2...1....1....1..1.1.24.3.1.2.1.1
hla0881         :::::::::::::::K::::::D:R::A:::::::::::::::::::::::::::D::::
VNG2053         ::::A:::::I::::EY:GA:G:D::::::::::::::::::::I:T:T::::L::::::
NP5080A         :::::::::::::::::::::S::::::::::::::Q:::::::I:::TA:::::D::::
Hut2927         :::::::R:::::::E:::::::G:::::::E::::::::::::::::T::::::::::V
rrnAC2829       :::::::R::::::::F::E:S:G:::::::E:::::::::::::::::::::::T::::
Hmu3134         :::::::R:::::::::::::S:D:::K::::::::::::::::I::::D:K::::::::
HVO_1899        ::::::::::::::::::G:::::R:::::::::::::::::::::::VN:N:::::T::
Hbo1777         :::::::::::::::E:::::::QR:::::::::::::::::::::::VN:::::::T::
HQ1337A         :::::Q:T:::::::::::::::QR::::::::::::::::I:::::::S:L::::::::

consensus       PNRPGVYYEAEFDALTFDPQMQEVVDGEVVEVVNFGAFVGIGPVDGLLHVSQISDEYLAY
#oth            1121....1.2...2.11.3....2..2...1.2....1..............1....11
hla0881         H:::::::::::::::Y::D::::A::T:::T:E:::::::::::::::::::T::::TF
VNG2053         ::::::::::::::V::E:E:::::::::::::S:::::::::::::::::::::::::F
NP5080A         ::::::::::::::V:::::::::::::::::::::::::::::::::::::::::::::
Hut2927         ::E:::::V:::::::::::::::::::::::::::::::::::::::::::::::::::
rrnAC2829       ::K:::::::::::::::::::::::::::::::::::I:::::::::::::::::::::
Hmu3134         ::K:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
HVO_1899        ::::::::::D:::I:Y::D:::::::I:::::E::::::::::::::::::::::::::
Hbo1777         :G:A::::::::::V::::D::::I::::::::E::::::::::::::::::::::::::
HQ1337A         :G:A::::::K:::I::::A:::::::::::::E::::::::::::::::::::::::::

consensus       DGENQQLASRESNRTLGVGDSVRARIVTKSIDERNPRDSKIGLTAKQPGLGKHGWLQEER
#oth            .111.1...21.121.311.2..1.1...........1.........1.....1..233.
hla0881         ::V::::::SD:DK::::D:A::V:V:::::::::::::::::::::::::::E::EGQ:
VNG2053         :E:::::::::::QV::T:::::::::::::::::::E:::::::::::::::::::AD:
NP5080A         :E::::::::D:::V:S:::::::::::::::::::::::::::::::::::::::E:::
Hut2927         ::::::::::D:::::T::::::::::::::::::::::::::::::V::::::::D:::
rrnAC2829       :E::::::::::::::T:::A::::::::::::::::::::::::::V::::::::::::
Hmu3134         :E:G:A:::::::::::T::A::::::::::::::::::::::::::V::::::::::::
HVO_1899        :::::::::T:::Q::A:D:E:::::::::::::::::::::::::::::::::::ESK:
Hbo1777         :::::::::T::::::A::::::V:V::::::::::::::::::::::::::::::EAD:
HQ1337A         :::::::::T:::::::::::::V:V:::::::::::::::::::::::::::::::AD:

consensus       QAREATAEAGD---
#oth            24333431234411
hla0881         :H::Q:G:EA::::
VNG2053         EQAD:AS:GE-:::
NP5080A         :R::--:Q::::::
Hut2927         K::---::::EN::
rrnAC2829       ER::G::::::S::
Hmu3134         EK:A:E:::::S::
HVO_1899        :QS::S::GN-:::
Hbo1777         ::S:::T::EGR::
HQ1337A         ::NA::T:::AEGK