[O] (GIM5) COG1730 Predicted prefoldin, molecular chaperone implicated in de novo protein folding 9 genomes BUD0428 9 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG2465 rrnAC3116 HVO_0119 Hbo1377 Hmu2642 Hut2030 hla2497 NP0184A HQ3420A

Pairwise sequence scores
Consensus score	1096	NP0184A	Hmu2642	rrnAC3116	VNG2465	Hut2030	HQ3420A	hla2497	HVO_0119	Hbo1377
774	NP0184A	1084	763	750	639	707	599	648	662	641
831	Hmu2642	763	1103	861	652	739	663	692	648	665
794	rrnAC3116	750	861	1127	652	690	607	677	615	640
794	VNG2465	639	652	652	1110	707	652	674	670	728
894	Hut2030	707	739	690	707	1127	740	774	748	738
808	HQ3420A	599	663	607	652	740	1128	797	771	804
879	hla2497	648	692	677	674	774	797	1112	812	820
859	HVO_0119	662	648	615	670	748	771	812	1138	879
868	Hbo1377	641	665	640	728	738	804	820	879	1116

163 symbols
consensus       -----GGGGGQQQ-LQQLSQELQAIEEEIEALEAEVEDLRNEQTEIDEAIEAIETLETGS
#oth            1123421...11111112212111211.42213311432241122.11.31.121.11.2
NP0184A         ::MSL:::::GGA:ME:IQ:Q:::L:Q:KQ:IQ::I:NV:D::S:::::::::::::::A
Hmu2642         ::::M:::::GG::M::IQ::IEQ::Q:Q::I:E:I:S::::::::::::::::::DS:D
rrnAC3116       MMGGG:::::GG::M::VA::IEQM:Q:V::IDE:I:R::EK::D:::::::::::DS::
VNG2465         :::MSL:::::::::::::::I::::::V:E:::D:AS::Q:::::E::K::LDV::::A
Hut2030         ::MSL:::::::::::EIA:AIE::D::R:E:::::Q::::K::::::::::::::::::
HQ3420A         :::::MM::::::Q:::::E:::::D:::DE:RE::D::QS:::S::::MD::Q:::S:A
hla2497         :::::MM:::::::::::::::::LD:::::::V:ID:H:E::SD::D::::::::DS::
HVO_0119        :::::MM:::::::::::::::::LD::::S:::::S::ND:KD:::::V::::::::::
Hbo1377         :::::MM:::::::::::::::::::Q:::E::GD:S::QQ:KS::::::::::::::::

consensus       TVQVPLGGDAYVRAEVQDIDEVIVSLGGGYAAEQEQDDAIESLERKQDALDDRIEDLQEE
#oth            ........1..2..213.2..12.2..1211..14334.323.43.2221.33.342342
NP0184A         ::::::::::::::TIE:M:::V:T::::::::RDSEG:V::::::KET::::::E:EG:
Hmu2642         :::::::::::L:::I:::::::::::::::::RAEAG::D:::T:::TI:::::::ESD
rrnAC3116       :::::::::::I::TIE:::::V:::::::S::R:::G:VST::T:KET:::H:S:::::
VNG2465         ::::::::::::::::K:M:::V:::::::::::DS:A:ASV:DE:KATI:G::D:V:A:
Hut2030         ::::::::::::::::L:M::IT::::AD:::::G::::TDT:::::::I::Q::Q:S::
HQ3420A         :::::::::::::::I::A::I::G::ADF::::SA:N:V:::ST::::::N:::S:RDD
hla2497         ::::::::G::::::::::::I::::::N:S:::SEE:::DV:G::R::::::::ET:::
HVO_0119        :::::::::::L::::::::::V::::AN:::::::ST:::T:R:::::::EE:ASVRGQ
Hbo1377         ::::::::G::L::D:::::::::G:::D::::::::::::A:RL:::SI:E::AAV:G:

consensus       IAELEEESEELEQQAQQMQQQMMQQQMQQMQQ-Q-----GDDE
#oth            232113.3432111.1.1...11..21.111242111133221
NP0184A         :ETV:::TAS::EK:::A:::Q:::-L::::::-:::::-E::
Hmu2642         :::::T:A:KMQ:::::::::Q:::M:::QEE:-:::::::::
rrnAC3116       K::V:T:M:::::::::::::Q:::M:::QE::-:::::-E::
VNG2465         ::D:S::A:Q:::::::A::::::::::AQ::P::::::DGEQ
Hut2030         :S::::::QQ:::::::::::Q::::::::::QE::::::GE:
HQ3420A         :D:::T::SQ::::::::::::Q::::::::DQ:::::PE:N:
hla2497         VD:::S::Q:::::::::::::Q:::::::::S::::::::E:
HVO_0119        :E::::::D:I:E::M:A::::Q:::::::::M:GEGDD::::
Hbo1377         :SD::D::S:::::::::::::Q:::::::::M:::::ED:::