[FGR] (Hit) COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases 9 genomes BUD0447 9 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG2186 rrnAC2638 HVO_0230 Hbo1357 Hmu2817 Hut2886 hla0443 NP5090A HQ3651A

Pairwise sequence scores
Consensus score	1067	VNG2186	hla0443	NP5090A	Hbo1357	HQ3651A	Hut2886	rrnAC2638	Hmu2817	HVO_0230
746	VNG2186	1090	619	598	575	633	587	703	654	609
850	hla0443	619	1159	699	726	642	634	662	693	740
765	NP5090A	598	699	1089	759	728	565	596	640	669
838	Hbo1357	575	726	759	1064	821	558	675	686	718
773	HQ3651A	633	642	728	821	1089	551	612	622	638
746	Hut2886	587	634	565	558	551	1082	694	785	647
817	rrnAC2638	703	662	596	675	612	694	1094	785	680
827	Hmu2817	654	693	640	686	622	785	785	1076	769
832	HVO_0230	609	740	669	718	638	647	680	769	1054

152 symbols
consensus       ---------MSDDCIFCQIVAGDIPARIVHETDDVLAFLDANPLAPGHTLVIPKAHHERL
#oth            111111112234211.12.22111.212.1.12241.....1.112.....1.1422331
VNG2186         ::::::::::::::V::::I:DE::::V:::DA:T::::::T:M::::::::::T:AAT:
hla0443         MGRRDDSSR::A:::::S::D::::::T::::::::::::::::::::::::::::AQHV
NP5090A         ::::::::::::RT::E::ID:::::::::::ETT::::::::::::::::V::EPY:::
Hbo1357         ::::::::::GEPT::E::A:::::::::Y:::T:::::::::::::::::V::EA::::
HQ3651A         ::::::::MSE:PT::E::A::::::::::::ETIV:::::::::::::::::RDAYTK:
Hut2886         :::::::::-MT::V::A::E::V:SDT::::::A::::::::::K:::::V::::::::
rrnAC2638       :::::::::::E:::::::::::::G:T:Y:D:T::::::::::S:::::::::::::::
Hmu2817         :::::::::::E:::::S::D::::G::::::::AV:::::::::R::::::::S:::::
HVO_0230        :::::::::-MS:::::A::D::::G:::::::QS::::::::::::::::V::E::A::

consensus       GDLPADVATDLFAAVHELTPAVEAAVDADATTVGINNGEAAGQEVPHVHVHIIPRFEGDG
#oth            4121314133232115412.2113....2131112.1.34.....1.1.3.21...31.2
VNG2186         A:T:G:D::AV:ETL:A:A:T:::::::::::I:F:::T::::::::::G::::::AD:D
hla0443         :::DD:L:S::::::T::::R:Q:::::EGAN::::D::::::::::::::V::::::::
NP5090A         R:::PELSA:V:ET:RTV::::QD::::::::I:::D:PE:::::::L::::V:::::::
Hbo1357         R:::D::::::W:::D::::R::D::::::L:::V:D::::::::::::::LV:::D:::
HQ3651A         ::::D::::E:W:T:QS:::TI:T::::::::I:V:::S::::::::::I::::::DD::
Hut2886         ::V:PEE:EGFY::L::VV:::::::::P::::AV::::P:::::::::A:V::::PD:S
rrnAC2638       N:T:::::SAVMSTL:::V::::S::::P:S::AF::::V:::::::::G:::::::D::
Hmu2817         D:V::EE::G:YS:L::VV:::::::::P::::AF::::D:::::::::A:VV:::::::
HVO_0230        DEV:::A:A::::::ND:V:R::::::::::N::::::P::::::D::::::V:::::::

consensus       GGPIHAVAGDRPDLSDEELDDIAADIAA----
#oth            13.2.243251.22114112412431466422
VNG2186         :::L:VA::T:::V::AD::AT::::TDRLA:
hla0443         :A:L:::G:K:::::E::::A::D:V::AIDE
NP5090A         :::::G:::KT:E:G:::::T::D:::EGLD:
Hbo1357         :::::::::S:::::::::::::ER:ET::::
HQ3651A         ::::::T::A::E:::S:::T::MN:ESTADL
Hut2886         A::V::LFT:::RIG:T:RES:V:::::NI::
rrnAC2638       :R:::VLVN::::I::D:::::EN::V:EQA:
Hmu2817         ::::::MF:S::::::D:::E:E:A:EP::::
HVO_0230        :S:::::::E:::::::::A::E:A:SG::::