9 genomes BUD0456 9 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG2163 rrnAC2748 HVO_0290 Hbo1192 Hmu2837 Hut2335 hla0386 NP5152A HQ3265A

Pairwise sequence scores
Consensus score	1005	VNG2163	HQ3265A	Hut2335	NP5152A	HVO_0290	Hbo1192	hla0386	Hmu2837	rrnAC2748
711	VNG2163	1006	595	636	672	709	663	645	631	642
749	HQ3265A	595	1071	636	711	724	759	736	664	685
819	Hut2335	636	636	1068	768	740	753	738	832	776
851	NP5152A	672	711	768	1038	780	807	799	802	789
870	HVO_0290	709	724	740	780	1033	884	831	742	767
889	Hbo1192	663	759	753	807	884	1070	888	770	766
893	hla0386	645	736	738	799	831	888	1011	781	759
822	Hmu2837	631	664	832	802	742	770	781	1092	880
831	rrnAC2748	642	685	776	789	767	766	759	880	1441

199 symbols
consensus       -------------------------------------------------MGNKNKTISFR
#oth            111111111111111111111111111111111111111111233333312.........
VNG2163         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
HQ3265A         :::::::::::::::::::::::::::::::::::::::::::MGSANTDK:::::::::
Hut2335         ::::::::::::::::::::::::::::::::::::::::::::::::::S:::::::::
NP5152A         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
HVO_0290        ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
Hbo1192         ::::::::::::::::::::::::::::::::::::::::::VTTFGRF:::::::::::
hla0386         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
Hmu2837         ::::::::::::::::::::::::::::::::::::::::::::::::::S:::::::::
rrnAC2748       MSVAIFADTEVGRRLNHSGSTVVRDGHQGTGPVASDKRLNTLLLKQYII:::::::::::

consensus       VNEDAFETLREIAEERDISLSAVFRDYVDTLVAHDGQVRVVPEHELE-----ATEDDDES
#oth            .1112.11.12.....1........1...3..3.2.2.3.2.121342133764354412
VNG2163         :::E::DA:S::::::N::::::::::::S::T:::K::::::DSTR::::::RDG::DD
HQ3265A         ::::V::::::::::::::::::::E::::::::E:A:Q::::::I:E:LRAGNG:TAD:
Hut2335         :S:EK::::::::::::::::::::::::M::D:S:K:E:::::::S::::GEA:S:::T
NP5152A         :::E::::::::::::::::::::::::::::::::::::::::::KSGSASE:A:AA::
HVO_0290        ::::::::::::::::::::::::::::::::::::::Q:::K::::::::KLR:GE:::
Hbo1192         ::::::::::::::::::::::::::::::::::::::Q::::::::::::QMNGN:E::
hla0386         ::::::::::D:::::::::::::::::::::::::::::I::A::::::::SMG:TG::
Hmu2837         :SQEK:::::G::::::::::::::::::L::::::::E:::::::N::EATD::ETT::
rrnAC2748       :S::K:::::::::::::::::::::::::::S:::::K:A::::F::::DD:::TST::

consensus       FPPKVEVPKSFVREHERLELEAEHLREQLEEHKRYVNKLREQLE---DDDEEVIQLEDLD
#oth            ...212.1.1.1.........11......1.2.3.223.2312332142521112..1.1
VNG2163         :::T:::S:::::::::::::::::::::D:Q:A:IDH::S:TDSE::EIGD:VK::E::
HQ3265A         :::T:T:::G:::::::::::::::::::::::Q:L:H:QD::-::::EE::I:H::::E
Hut2335         :::Q:::::::I:::::::::SD::::::::Y::::T::::EVN:::G:::DI:::::::
NP5152A         :::::::::::::::::::::::::::::::Y:Q::T::SQ:V:E::QEA:D::::::::
HVO_0290        :::T:::::::I:::::::::::::::::::::G:::Y::::V:NDH::V::::::::::
Hbo1192         :::::K:::::I::::::::::D::::::::::::::Y::::::::::EE::::::::::
hla0386         ::::I:::::::::::::::::D::::::::::::::Y::::::::::G:::::::::::
Hmu2837         ::::::::::::::::::::::D:::::::::::::TQ::Q::DE::H:Q:DIV::::::
rrnAC2748       ::::::::::::::::::::::::::::::::::::T:::Q::DE::M:QD:::H:::::

consensus       GE-DDEES-FRLG------
#oth            5436123111111211223
VNG2163         --:::D:P:YQ::::::::
HQ3265A         RSET:SQ:::::E::::::
Hut2335         ::QE::::AY:I:EFDEPV
NP5152A         :DESE::P:::::::::::
HVO_0290        T-:G::P::::::::::::
Hbo1192         AD:A::P::::::::::::
hla0386         :::P::P::::::::::::
Hmu2837         ::D::DA::Y:I:SFDDLD
rrnAC2748       QGEEEDA::Y:I:SFDDLE