[S] (-) COG1624 Uncharacterized conserved protein 9 genomes BUD0467 9 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG1389 rrnAC1103 HVO_1660 Hbo3176 Hmu1616 Hut0989 hla1819 NP4194A HQ2563A

Pairwise sequence scores
Consensus score	1988	VNG1389	rrnAC1103	Hut0989	Hmu1616	hla1819	HQ2563A	NP4194A	HVO_1660	Hbo3176
1479	VNG1389	1996	1368	1345	1336	1420	1331	1430	1353	1419
1623	rrnAC1103	1368	1994	1491	1581	1533	1433	1505	1500	1484
1584	Hut0989	1345	1491	1977	1530	1441	1336	1509	1464	1458
1686	Hmu1616	1336	1581	1530	1998	1553	1453	1515	1518	1508
1673	hla1819	1420	1533	1441	1553	1992	1509	1497	1529	1553
1645	HQ2563A	1331	1433	1336	1453	1509	1998	1471	1540	1595
1693	NP4194A	1430	1505	1509	1515	1497	1471	1984	1512	1525
1714	HVO_1660	1353	1500	1464	1518	1529	1540	1512	1994	1693
1732	Hbo3176	1419	1484	1458	1508	1553	1595	1525	1693	2003

272 symbols
consensus       -MAALSDLLDDLVADVDALFLFSPSGSFYERFADADT--EVVVVAPENTVDAETFVELPL
#oth            1.4524131322321411223.2.23.413324252523331.1131.423.2311...1
VNG1389         ::TRPP:::A:VLDGI:::LV::::::Y:D:VD:VEG:VD:::::T::A:G:::::::::
rrnAC1103       ::NE:R:::G::::::::V:::::NA::F:E:D:V:E:::I:::G::::L:::P:::::I
Hut0989         ::SQID:V:GR:S::L::I:::A::N:L:DEL:E:Y:::-:I::GA::GP:::R::::::
Hmu1616         M:S::REF:::I:::T::V::::::A:L:QS:E:D::::::::I::::::::::::::::
hla1819         :::S:T:H:S:::EGA::VL::::TS::FN::E:G:::::I:::::D:D::::V::::::
HQ2563A         :::V::::V::II::IQG:VM:::T::R::::IN::LEYPII::::::N:N:A:YI:::I
NP4194A         ::SE:::::::I:::::GV:::::::::::::GES:P::--:::::::D:G:DRY:::::
HVO_1660        ::::::E::G:::::::G::::T::S:H::Q::ET:V::PT::I::::::E:::::::::
Hbo3176         ::V:::::::NV::::::::I::::S:Y::::::::LDTP:::::S::A:::::YI::::

consensus       EFDNVRDRIRFGIEGALEQEIVAEGDEVACNVAVFDDDPDSVVRVRVGEFMRSGVYDLFV
#oth            4.3245212...1..122624.4221523.4464232461322.12252554111.21.1
VNG1389         A::D::EQ:::::::::SEGV::D:::LG:VAPFLSEEV:M:T:T:ANAGTQ:S::E::A
rrnAC1103       D:TDLEG:L::::::::::G::D:::::L:VTE:L:GAENTL:::QTND:SP:::::M::
Hut0989         D:TAID::V:::V:::::K:Y:M:T:DIL:LGRTYA:EL:TI::::A:::VE::::::::
Hmu1616         ::T:MA::::::V:::::::Y:E:DAD:V:IGD::::T:::I:::Q:A::SP::::G:::
hla1819         P::::K::::::::::MDA:L:S:::::V:IAS:::GGS:A:I::T:D:TVHT:I:::::
HQ2563A         :::DA::Q::::::::I:SG::::::A:V::LSI:::G:::L:::Q:::SI:::I:::::
NP4194A         A:KD:SE::::::::G::H:F:::::Q:::A::L::::I:T:T:::A:D:DQ::::::::
HVO_1660        Q:Q::K::::::V:::M::S::EA::TI::::GT:GG::::L:::::E:N::::I::::A
Hbo3176         ::::::::::::V:::M:NGV:E:D:I::::::::GG:Q:A:I::::T:E::::I::::A

consensus       NSRAEPSVIRDVFEVAIELGKKGQKGKPVGALFVVGDAGKVMNKSRPLSYNPFEKSHVHV
#oth            11..122.111.12..1...2.....11.....1........1...............1.
VNG1389         ST::::G::::::D::::::R:::::::::::::::::::::T:::::::::::::::::
rrnAC1103       ::::DA::V:::::::::::::::::::::::::::::::::::::::::::::::::::
Hut0989         ::::::G:::N:L:::V:::::::::::::::::::::::::::::::::::::::::::
Hmu1616         :::::::::N::LD::::::::::::::::::::::::::::::::::::::::::::::
hla1819         ::::::::::::::::::::Q:::::::::::::::::::::::::::::::::::::::
HQ2563A         ::::DS:::::::N::::::::::::::::::::::::::::::::::::::::::::::
NP4194A         ::::::E:::N::::::::::::::::R::::::::::::::::::::::::::::::::
HVO_1660        ::::D:G:::::::::::::::::::E::::::I::::::::::::::::::::::::Y:
Hbo3176         ::::D:::::N:::::::::::::::::::::::::::::::::::::::::::::::::

consensus       GDPIVNVMLKEFSRLDGAFVISDSGKIVSAYRYLEPSAEGVDIPKGLGARHMAAGAITRD
#oth            .....2.............11..2.....1......2...1............11.1..1
VNG1389         :::::::::::::::::::::::::::::S::::::G:::T:::::::::::::::::::
rrnAC1103       :::::::::::::::::::::::A::::::::::::::::::::::::::::::::V:::
Hut0989         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::V:::
Hmu1616         :::::::::::::::::::::::G::::::::::::::::::::::::::::::::V:::
hla1819         ::::::::::::::::::::V:::::::::::::::G::::::::::::::::G::::::
HQ2563A         :::::K:::::::::::::IV:::::::::::::::G::::::::::::::::GA::::E
NP4194A         :::::D::::::::::::::::::::::::::::::::::::::::::::::::::::::
HVO_1660        :::::::::::::::::::::::::::::::::::::::::::::::::::::G::::::
Hbo3176         :::::::::::::::::::I::::::::::::::::A::::::::::::::::GA:::::

consensus       TNATAIVLSESDGLVRAFKGGELILEIDPEEY
#oth            .11211............23.2211.2...31
VNG1389         :::V::::::::::::::RN:::V::L:::DN
rrnAC1103       :M:::::::::::::::::::::V::::::::
Hut0989         ::::::::::::::::::::::::::L:::::
Hmu1616         :::I:::::::::::::::S::::::V:::::
hla1819         :::::::::::::::::::A:::V::::::::
HQ2563A         ::S:T::::::::::::::S::::F:V:::V:
NP4194A         :::V:V::::::::::::S:::I:::L:::::
HVO_1660        :::::::::::::::::::::KM:::::::A:
Hbo3176         ::::T::::::::::::::::QM:::::::D: