9 genomes BUD0472 9 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG1479 rrnAC0876 HVO_2705 Hbo2426 Hmu1781 Hut0877 hla0784 NP4336A HQ2714A

Pairwise sequence scores
Consensus score	587	Hmu1781	NP4336A	hla0784	rrnAC0876	HQ2714A	Hut0877	VNG1479	HVO_2705	Hbo2426
394	Hmu1781	591	356	316	257	305	338	244	266	340
408	NP4336A	356	708	343	214	399	362	278	262	404
438	hla0784	316	343	812	268	345	345	272	325	389
298	rrnAC0876	257	214	268	427	222	281	272	287	263
458	HQ2714A	305	399	345	222	1789	389	306	295	428
477	Hut0877	338	362	345	281	389	584	325	285	385
333	VNG1479	244	278	272	272	306	325	435	273	316
347	HVO_2705	266	262	325	287	295	285	273	579	405
472	Hbo2426	340	404	389	263	428	385	316	405	694

237 symbols
consensus       ---------------------------------------------------------V-P
#oth            111111111111111111111111111111111111111111111111111111113443
Hmu1781         :::::::::::::::::::::::::::::::::::::::::::::::::::::::::MPH
NP4336A         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::MPTR
hla0784         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::Q:
rrnAC0876       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::-:-
HQ2714A         MSTGELKYRVSAFISILVLKISSLILTELGHSADLISGSHQHRLNRYYFEDCDEDSF:E:
Hut0877         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::VAE:
VNG1479         :::::::::::::::::::::::::::::::::::::::::::::::::::::::::-:-
HVO_2705        :::::::::::::::::::::::::::::::::::::::::::::::::::::::::-:-
Hbo2426         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::PR

consensus       VERTDPDGVDYGWVMQTTFVVTILVGAPIVAVLSLGVTLPTWAARAEFAIRVGAVIWFLT
#oth            223232212132111.2...2..22.1.3.231.3434.32.34116..1.1..31.231
Hmu1781         ::E:::E:::F:::::M:::T::::::::::T:::F:Q:TG::EW::::::::::V::C:
NP4336A         ::T:::::::::::::::::L::I::::V::A:::L:E::::GQ::N::::::::V:LCL
hla0784         :::AEYE:I::A::::::::::::::::V:::::VF:::DS:P:::A::V::::P:::A:
rrnAC0876       --------------::V:::T:::::S:L:VLA:TA:::Q::T:::L::V::::L:::::
HQ2714A         ::T:::::::::::::::::L::II:::V:T:::::A:::::GT:VG::::::::::I::
Hut0877         SA::::::::H:::L::::::::VL:::::::::::QS::::T:::T::::::::V::::
VNG1479         --------------:::::::::V::::::TA::T:YS:::::S:VS::V:I::I:::::
HVO_2705        --------------::M:::T:::::S:::::::VNAG:Q::G:::::::::::::::V:
Hbo2426         ::::N:::::::::::::::::::::S:T::A::IAYE::::::::S::::::::::I::

consensus       AVGVFVYARRTRA-----------------------------------------------
#oth            135225.12143322223211111111111111111111111111111111111111111
Hmu1781         :A::YA::-:Y:E:::::::::::::::::::::::::::::::::::::::::::::::
NP4336A         GI:::F::::DAG::::AG:::::::::::::::::::::::::::::::::::::::::
hla0784         ::A:A::::::D:GDGGVA:::::::::::::::::::::::::::::::::::::::::
rrnAC0876       ::C:YL::-:Y:::::::::::::::::::::::::::::::::::::::::::::::::
HQ2714A         :LS::G:::WSDTNTDTNGVDTESVNTPSASSEKSTSDVSSRTHVDSHTNTNTNTNTNTN
Hut0877         :::::::E::Y:::::::::::::::::::::::::::::::::::::::::::::::::
VNG1479         ::T::A::::HA::::::::::::::::::::::::::::::::::::::::::::::::
HVO_2705        ::VL::::K::N::::::::::::::::::::::::::::::::::::::::::::::::
Hbo2426         :ISA:I::K::D::::::::::::::::::::::::::::::::::::::::::::::::

consensus       -------------D----P--------------------------------------
#oth            111111132222323333243332322233221111111111111111111111111
Hmu1781         :::::::::::::-::::-::::::::::::::::::::::::::::::::::::::
NP4336A         :::::::QADSDGESGDETR:::::::::::::::::::::::::::::::::::::
hla0784         :::::::EADDDP:AADD:GGAEKVDEDAGDA:::::::::::::::::::::::::
rrnAC0876       :::::::::::::-::::-::::::::::::::::::::::::::::::::::::::
HQ2714A         TNTNTNTNTNSNS:ADMD:DPNPDPSIDIDSHSNTETGTSQTTQQNSDTTTAAEETS
Hut0877         :::::::::::::-::::-::::::::::::::::::::::::::::::::::::::
VNG1479         :::::::::::::-::::-::::::::::::::::::::::::::::::::::::::
HVO_2705        ::::::::::::G:GGTP:EAELDTDIDAED::::::::::::::::::::::::::
Hbo2426         ::::::::::::G:GGTP:EA::::DIEMDD::::::::::::::::::::::::::