[B] (HHT1) COG2036 Histones H3 and H4 9 genomes BUD0522 9 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG0134 rrnAC2301 HVO_0520 Hbo0999 Hmu0094 Hut2967 hla0412 NP0316A HQ1436A

Pairwise sequence scores
Consensus score	1045	VNG0134	Hut2967	rrnAC2301	Hmu0094	NP0316A	HQ1436A	HVO_0520	Hbo0999	hla0412
733	VNG0134	1093	678	653	697	714	705	711	734	731
779	Hut2967	678	1048	771	782	742	681	724	712	718
838	rrnAC2301	653	771	1060	866	801	747	740	770	780
867	Hmu0094	697	782	866	1062	826	722	767	813	791
862	NP0316A	714	742	801	826	1066	750	770	792	779
855	HQ1436A	705	681	747	722	750	1045	810	841	817
924	HVO_0520	711	724	740	767	770	810	1041	870	859
947	Hbo0999	734	712	770	813	792	841	870	1040	923
929	hla0412	731	718	780	791	779	817	859	923	1038

153 symbols
consensus       MSVELPFAPVDSIIRRNAGGLRVSADAAEELARRIQDHGAELAIDAAERATADGRKTLMA
#oth            ...........32..22..4.....2.1.1.11...52.15..31..33.32.1.....1
VNG0134         ::::::::::::L::GH::D:::::G::::::::::R:::I::V:::AA:RE::::::::
Hut2967         :::::::::::::::::::::::::E:T:A:T::::SR::T::A::::A:S:::::::::
rrnAC2301       :::::::::::AV:::::::::::::::::::::::::::S::VT::TE::T:::::::P
Hmu0094         ::::::::::::V::::::::::::E::::::::::EY::R::A::::T::::::::::P
NP0316A         :::::::::::T:::::::Q:::::E::::::::::::::A::ET:::::::::::::::
HQ1436A         :::::::::::T:::GK::E:::::G::::::H:::T:::T::VT:::E:DT:D::::::
HVO_0520        :::::::::::A:::Q:::E:::::G:::A:::::::R:::::::::D::::::::::::
Hbo0999         :::::::::::T:::::::S::::::::::::::::R::S::::::::::RE::::::::
hla0412         :::::::::::G:::::::D::::::::::::::::A::::::::::::::E::::::::

consensus       EDF-GVEQVVD------RDELELPVAPVDRIARLRIDDRYRVAMDARIALADILEDYADN
#oth            3..11353143111111143.3..1..1......2..131..22...1...23..31.33
VNG0134         S::E:IVGPR:DTAPDR:GD:A::::::::::::E::::F::SE:::V:::GV::A::AD
Hut2967         M:::::GE:PE::::::K:A::::I:::::::::D::::::::::::::::S:::RE::D
rrnAC2301       A::::I:::PE::::::K:G::::::::::::::D:::D::::::::V:::SL::T:::E
Hmu0094         ::::DT:G:R:::::::K::::::::::::::::D:::S::::::::V:::::::A:::D
NP0316A         :::::-STPG:::::::K::::::::::::::::D:::::::S::::::::GE::A:::T
HQ1436A         A:::::R:::P:::::::R:::::I::I:::::::::NQ:::S:::::::::::::::N:
HVO_0520        ::::::Q::::::::::::::S::I::I::::::::::::::::::::::::::::::V:
Hbo0999         ::::D:::::S:::::::A:::::::::::::::::::::::S:::::::::::::::::
hla0412         S::::::::IS:::::::ED:I:::::I::::::::::::::GV::::::::::::::::

consensus       VADAAAILARHADRRTVQAEDIETYFEL---FE
#oth            2.31.25..2..1...1112.111.34.43221
VNG0134         I::G::V::E::G:::::::::Q::VT::::V:
Hut2967         ::A::SL::E::G::::K:::V:L:AQ:THYV:
rrnAC2301       T:A:::A:::::::::IK:A:V::::::EQYY-
Hmu0094         ::A:::T:::::::::IK:::V::::::RQYY-
NP0316A         ::T::::::::::::::K:D:::::Y::KPH::
HQ1436A         ::::::::::::::::I:::::::::Q::::::
HVO_0520        :::::VK::H::::::::S:::::::S::::::
Hbo0999         ::::::K:::::::::I:::::::::A::::::
hla0412         ::S:::T:::::::::::::::::::A::::::