[S] (-) COG1303 Uncharacterized protein conserved in archaea 9 genomes BUD0550 9 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG0755 rrnAC0857 HVO_1173 Hbo0386 Hmu1538 Hut0973 hla1566 NP4110A HQ2492A

Pairwise sequence scores
Consensus score	1386	HQ2492A	VNG0755	rrnAC0857	Hmu1538	Hut0973	NP4110A	hla1566	HVO_1173	Hbo0386
1006	HQ2492A	1488	966	817	812	789	825	878	950	966
1079	VNG0755	966	1604	870	880	886	897	919	1007	1015
1070	rrnAC0857	817	870	1371	1038	982	995	932	989	959
1042	Hmu1538	812	880	1038	1415	1061	991	862	984	941
1032	Hut0973	789	886	982	1061	1352	972	857	976	954
1081	NP4110A	825	897	995	991	972	1364	955	1030	1014
1128	hla1566	878	919	932	862	857	955	1832	1043	1061
1234	HVO_1173	950	1007	989	984	976	1030	1043	1385	1180
1218	Hbo0386	966	1015	959	941	954	1014	1061	1180	1464

244 symbols
consensus       ---------------------------------------------------MHDEPEVAV
#oth            132121221222221211111111111111111111111111111111111135323.31
HQ2492A         MK:::::::::::::::::::::::::::::::::::::::::::::::::RSC:ND:S:
VNG0755         MGRSETRTPTAHLPGR::::::::::::::::::::::::::::::::::::QSH:::::
rrnAC0857       ::::::::::::::::::::::::::::::::::::::::::::::::::::K:S:Q:T:
Hmu1538         ::::::::::::::::::::::::::::::::::::::::::::::::::::QG::::::
Hut0973         ::::::::::::::::::::::::::::::::::::::::::::::::::::Q:::A:VI
NP4110A         :::::::::::::::::::::::::::::::::::::::::::::::::::::G:N::V:
hla1566         MNLSLTWSPLSGFDGNDPRSWLYSSEGLPSRRTAPTSPHRKDHAARGRTAG:::AR::V:
HVO_1173        :::::::::::::::::::::::::::::::::::::::::::::::::::::N::::::
Hbo0386         :::::::::::::::::::::::::::::::::::::::::::::::::::::E::::::

consensus       LRYGHRPGRDDRMTTHVGLTARALGADRVILPDNAGQSAETVEDITDRFGGPFDVELTDE
#oth            ..1.......2................2232231155342.13..12......3.13125
HQ2492A         :::::::::::::::::::::::::::Q::F::::T::::::S::VS:::::::::R::G
VNG0755         :::::::::::::::::::::::::::::LF::::T:A::::R:::G:::::::::R:T:
rrnAC0857       ::L:::::::E::::::::::::::::K:V:ANA:RNQ:D::I::::::::::::AS:E:
Hmu1538         ::L:::::::E:::::::::::::::::LV:ANAGASRQD::::::::::::::::V:EQ
Hut0973         ::L:::::::E:::::::::::::::::I::ESA:EGRR::I::::::::::::::V::S
NP4110A         ::L:::::::N::::::::::::::::::SIAGA:SD:KA:I:::::::::::E::::T:
hla1566         ::::::::::::::::::::::::::::::F:::::::::::R::::::::::A:::R:D
HVO_1173        ::::::::::::::::::::::::::::::::::::H:M:::::::G::::::E::::EA
Hbo0386         ::::::::::::::::::::::::::::::::::::::K:::::::G::::::G:::::A

consensus       LNALIRDWEGVVVHLTMYGERVQDVEADIRE-AHREEPLLIVVGGEKVPFEVYERADWNV
#oth            232522313.312......222.3.2321.225355412.211.1...1321.15..2.1
HQ2492A         :::T::E:S:T:I::::::::::::TEV:::TCLHHQ::::II::::::SD:::W::::I
VNG0755         :::T:E::P:::::::::::QL:S:DDE::T:T:::::V:V::::::::GD:::A:::::
rrnAC0857       PKR::::F::R:::::::::P::E::::V::::NTA::::V:::A:::::::::H:::::
Hmu1538         P:RFLK::S:SIA::::::LP::E::GE::A::::S::::L:::A:::S:::::::::::
Hut0973         PLGRL:S:::SI:::::::QP::R::DE::A:S::K::::V:::A:::S::::D::::::
NP4110A         PR::V:::A:T::::::::Q:I::::::::::::ASG:V:::::A:::::D:::Q::Y::
hla1566         QK:IV:NF::::::::::::::::::G:V::SIQGGDG:::::::::::WAL:::::F::
HVO_1173        ::GV::N:::R:::::::::::::::::::::::A:::::V:::::::::::::G:::::
Hbo0386         :::V::N:::::::::::::::::::E:V:::V:E:T:I:::::::::::::::H::Y::

consensus       GVTNQPHSEVAGLAVFLDRLFDGRELDREWENADRRVVPQATGKRVVDADEE--------
#oth            1........1.2.1.......2.21.1111121132.3.323..3.22224553353331
HQ2492A         A::::::::::::::::::::M:Q::EQ::AG:EHV:::::C:::::::ELTTEADEMNA
VNG0755         ::::::::::::::::::::::::::EQGY:::E:::I:EEL::H:::VEDGDHAEGAAA
rrnAC0857       :::::::::::S:::::::::E::::::::::P::V::::E:::::::P:::::::::::
Hmu1538         :::::::::::::::::::::E:::::::::D:::V:Q::PE:::::P:E:AAETADE::
Hut0973         :::::::::I:A:S:::::::::::::::::D::K::::KE:::::EE:E--::::::::
NP4110A         :::::::::::::::::::::E::Q::::::::::::::KE:::::EPV:::::::::::
hla1566         :::::::::::::::::::::E:T:::::::D:::::M:E::::T:I:::::RSDGD:::
HVO_1173        :::::::::::::::::::::::::::::::D:EN::::M::::K::P::::::::::::
Hbo0386         :::::::::::::::::::::::::::::::::::K:I:K::::K::EPGADGEASDADA

consensus       ----
#oth            3322
HQ2492A         EK::
VNG0755         GDGD
rrnAC0857       ::::
Hmu1538         ::::
Hut0973         ::::
NP4110A         ::::
hla1566         ::::
HVO_1173        ::::
Hbo0386         TEDA