[S] (-) COG1945 Uncharacterized conserved protein 9 genomes BUD0551 9 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG1999 rrnAC3199 HVO_1958 Hbo1827 Hmu2564 Hut0259 hla1242 NP4484A HQ3114A

Pairwise sequence scores
Consensus score	1176	Hut0259	Hmu2564	rrnAC3199	VNG1999	NP4484A	hla1242	HQ3114A	HVO_1958	Hbo1827
728	Hut0259	1187	666	728	515	617	599	590	630	637
757	Hmu2564	666	1159	758	508	586	591	562	564	567
795	rrnAC3199	728	758	1162	589	644	634	599	614	602
739	VNG1999	515	508	589	1220	590	636	616	627	628
785	NP4484A	617	586	644	590	1211	663	574	628	646
863	hla1242	599	591	634	636	663	1363	740	725	746
807	HQ3114A	590	562	599	616	574	740	1253	758	791
868	HVO_1958	630	564	614	627	628	725	758	1156	894
904	Hbo1827	637	567	602	628	646	746	791	894	1161

195 symbols
consensus       --------MNTIRVVWGTGTAPTAMASYDAALAAANIHNYNLVAVSSVIPADATVEVVDT
#oth            11111111142.3113.31312.22111.....2.12.....231...1.1122114222
Hut0259         :::::::::G:::I:S:S:HG::PT:A::::::::GV::::::TL:::V:G:::I:R:G:
Hmu2564         :::::::::SV::I::::AGG::ELS:F:::::D:G:::::::TL:::::::PEI:::G:
rrnAC3199       :::::::::S::::::::A:G:::L:A::::::E:GV:::::ISL::::::EP:I::TE:
VNG1999         :::::::::PR::IA::S:V:::E::A::::::D::V:::::IR:::::::::::SP:::
NP4484A         :::::::::GR::I::::A:::::::::::::::::V:::::::::::V::::DI::AG:
hla1242         ::::::::::::H:AG:V:V:D:::::::::::D::L:::::::::::V::E::::A:EA
HQ3114A         MTCHRYEYVK::F::R:A:H:S::::::::::::::::::::TT:::::::E::::::E:
HVO_1958        :::::::::::::::R:V:::::E::::::::::::::::::::::::V:::::::A::V
Hbo1827         ::::::::::::Y::R:V:::::E::::::::::::::::::::::::::::T:::E:::

consensus       APDLGPAGNRLTVVEARATTAPGG-------------------------RVAAGLGWARG
#oth            ......3.35.31.12251244533111111111111111111111112522.111.234
Hut0259         ::::::::QG:Y::Q:AE:AEE:E:::::::::::::::::::::::::-A::AI::T:E
Hmu2564         ::::::V:AE:HT::SS::A:::E::::::::::::::::::::::::::::::I::S:S
rrnAC3199       ::::::P:EA:E::QSS::V:::E::::::::::::::::::::::::::G:::I::::S
VNG1999         :::::::::T:::::::GQ::GP::::::::::::::::::::::::::QAS:::A::PR
NP4484A         ::::::D:E::::::G:T:VP:EKD:::::::::::::::::::::::RSA::A:::::D
hla1242         :::::::::Q:::::::R:VG:DDAVDFREGGRAGAEDAESKRAPRRRPD::::::::T:
HQ3114A         ::::::V::Q:::::::M:::ET::::::::::::::::::::::::::Q:::::::TT:
HVO_1958        ::::::::::::::Q::E:::TP:E::::::::::::::::::::::::T:V::::::T:
Hbo1827         ::::::::::::::::::::SDA::::::::::::::::::::::::::T:S:::::TV:

consensus       P-GPGLFYEVSG-TDPDDVRARIEAGLAAGRDLRDWDFDDEEVAVETADA--DDEEYTTA
#oth            4311.1...131133324.264243.141.441.1.434335262332432233332121
Hut0259         :D:::I:::::::SNKQT::EDVR::::::::::::::GETQ::L:::S:DGA::A:A::
Hmu2564         ES:R:I:::::::E:::::::E:::::::::Q::::T:V:T:TV:RAVE-::A::::AS:
rrnAC3199       ED:::I::::D:::SE:A::ME:RE:::::::::::E:VE:N:Y::S:S-::::A::AS:
VNG1999         DGA::::::AADE:T::::AD:VTT:IT::M:V::::GVEPS:RT::VT::::AG:HAA:
NP4484A         SD:::I:::::::S:::A:EK:LD:::D::LE::E::C:VTGRR:VH::::::PDG::::
hla1242         ::::::::::T::E::::::E::::::D::S:::::ELP:R::H::::A:::TPDRF:::
HQ3114A         A::::::::AT:::::ES::QT:DD::SS:AT::::S:T:RR:IT:::ERNP:AG::::V
HVO_1958        S::::::::A:::::E:S:::AVID::E:::N::E:S:::::::LT:GTH::EG:G::::
Hbo1827         :::::::::A:::A:AEE::HA:::::SS::N::::Q::N:R:TTT:::::::G:G::::

consensus       VVIAAYGESEPLF--
#oth            213.2..3.323333
Hut0259         I:L:V::R:HS:IES
Hmu2564         ::C::::R:RLGL::
rrnAC3199       ::L:T::::H:VV::
VNG1999         :::::::D:D:V:DQ
NP4484A         L:L:V::D:D::L::
hla1242         :::::::::::IL::
HQ3114A         ::::::::::S::RD
HVO_1958        :TV::::Q::SV:::
Hbo1827         ITV::::Q:::I:::