9 genomes BUD0626 9 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG1227 rrnAC0120 HVO_2793 Hbo2527 Hmu1224 Hut0873 hla1291 NP3086A HQ2966A

Pairwise sequence scores
Consensus score	1850	Hut0873	NP3086A	VNG1227	rrnAC0120	Hmu1224	hla1291	HQ2966A	HVO_2793	Hbo2527
987	Hut0873	1777	669	737	796	756	671	720	748	725
1121	NP3086A	669	1842	826	878	845	763	808	818	820
1125	VNG1227	737	826	1868	870	794	789	910	844	879
1153	rrnAC0120	796	878	870	1837	995	817	865	951	834
1123	Hmu1224	756	845	794	995	1762	806	794	949	868
1176	hla1291	671	763	789	817	806	1854	963	1024	1046
1205	HQ2966A	720	808	910	865	794	963	1862	974	1141
1303	HVO_2793	748	818	844	951	949	1024	974	1864	1135
1311	Hbo2527	725	820	879	834	868	1046	1141	1135	1867

260 symbols
consensus       MTVVAVLADPPRPGLVLPELAETTPLSEAEAADLYAAMLADVCEAVDRSGGELLVNYRPD
#oth            1323432221.43.41244.2343212351122..42325.535.133.121.....145
Hut0873         :AT:V:R::A:IS:TA::H:VAE:::T:R:::E::QSA:Q::::::AG::AD::::::ER
NP3086A         ::T::::C:::Q::A:::::V:G::V:PED:::::T:L:C:TV::::G:::::::::::A
VNG1227         :P:A:::V::::D:::::T:PDE::::PS::TR::E::V::ILH::AE:NS:::::::::
rrnAC0120       ::T:T::::::VE:F::QD::GGI-VDD::::E::E:::L:::R::EI::A::::::::S
Hmu1224         ------M:E::ES:A::TD:V:HDR:TPD::SE:::G:F::::::I:G::A:::::::A:
hla1291         ::::::::K:::E:::ATG:::S::::A:::::::E:LFR:AVL:::::::::::::PVN
HQ2966A         ::::CI::::::::V:FET::::S::::S:T:E::D:I:R:MLI:::::::D::::::S:
HVO_2793        :::I::::E::::::::S:::::S:::::::::::::::K:::I::E::::D::::::AE
Hbo2527         :::::LM::::::::::S:::::S::::T::::::::::K:SMV::S::::D::::::SE

consensus       DQLPDEY---DGDAEAEVRTLVADALDDP--DEARFEVQVGSTFAARAGNTVTHLL-ERE
#oth            1423453256244313421433332123311341.1.2...11421.2...32...1251
Hut0873         :EIE:NV:::----::DL:DV:TT:::::::EA::::::::::P:::I::::::::::S:
NP3086A         EAV----:GV::::::II:EAI::VV:T-:::D::::::::E:::G:V:::A::::::T:
VNG1227         :::::AV::P:::::S:::A::D:::::DQHEA::V::::::SRS::V::::::::::NG
rrnAC0120       E:V::GV:::--:P:TA::EP:TE::ES:::GN::::::::::::G:V:::::::::D::
Hmu1224         E:VSS:-:::::TS:R:::SALDGVV:T-::::V:::::::::ES::::::I::::::::
hla1291         :D::A:::RT:AAP:::L::::::T:GGT::E:V:::R::::S:G::::::::::::RE:
HQ2966A         :A::EK:VDSNES:ATT:G:V:SET::::::SV::V:::::::::G:V:::::::::RD:
HVO_2793        :E::::F:AG:H:S:::I:SV:::::GGT:::N::::P::::::S:::::::S:::N:E:
Hbo2527         :L::EA:REE::T:::A::::A:::::::::S::::::::::SVS::::::MM::::RD:

consensus       GVRSVAVVRPTAPLLARTDIDSAAMKLRSNEVVLGPSTGGRVYYAGFTEPIDFTDAFATP
#oth            3351112231422325.461.211.1..233..2..134.223211.4221..4333431
Hut0873         :ES:::ILD:::V:A::PRL:Q:S:Q::R::::V:::VN:E:F::::::S:::SGIDGRL
NP3086A         ELS::GII::EVATF::::::::::::::CD::I::::::::H::A:G:::::::CY:A:
VNG1227         :AQ::::IE:D::T:L:K::::::::::RS::::::AD::D::F::::::V::KR:LEA:
rrnAC0120       D:AT::A:E:::A::N:QL::::::::::SG:::::AA:::::::::G:::::E:SY:::
Hmu1224         :::TA:::::::A::G:QH::T::::::::G:::::::A:::S::::A:::::E:::Q::
hla1291         NAD:::I:T:Q::M:S::V:::::::::T:::::::::R::T::::::A::::DG::EA:
HQ2966A         :AQ::::IE::T:F:L:ST::T:::Q:::::::::::A:::::::::::A:::::::E::
HVO_2793        E:H:A:::::I::::G::HL:::::::::TP:::::::E::::FS::LD:::::::Y:E:
Hbo2527         D::TA::::GD::FFT:SK:::M:::::T:::::::::A::S:V:::SD::::SE::T::

consensus       AVETLTARANDAGLDVDFLEMQPTLRTGADLATAVPLLRARWAAGRLVPEHTAAFIDELG
#oth            4221245.271.223132134633344453.5232352.11762323..72122425351
Hut0873         DI::IVD:::::::A:ST:::A:::::A:Q:RS:L:V::::RVG:LP:::R:V:RLE:::
NP3086A         ::::::N:CL:::H::E:::TKQSV::PQE::D:IVSV::HDT::E:::R:F::W::GMP
VNG1227         :::NVN:::V:::Y:::::PGRRRIGSARA:Q:L:AAI:::H:S:::::A::T:I:ES::
rrnAC0120       T:K:IGE::G:::::::::PPSAV:E:R:::E:I:::::::NR:::V::VR:T::L:D::
Hmu1224         T::::VQ::T::::A::::QTI:VVERD:::S:V:S:::::SR:D::::TR:T:AL::F:
hla1291         NLP::A::GR::D:::E:::SS:SMVD:D::LD::::::::F::Q:V::DY::::VH:H:
HQ2966A         :I::::D::SA:SY::A::DS:::IKHDS::::VIANI::::H:E:V::K:::E::IDT:
HVO_2793        E::::AR::D:::HGL:YVP:L:V:E:::::::V::M::S:VESE:::::::TT:VF:E:
Hbo2527         E::::::::::::HN:A:::::::V:::V::L:L::AI::::Q:E:I::GY::E:VV:T:

consensus       LRVV-DEDGLATVVRD----
#oth            34243432154523152211
Hut0873         ::T:EN::SEIS:E:S::::
NP3086A         YE::T:D:::SL:---::::
VNG1227         :::AA::S::PALR:T::::
rrnAC0120       I::I::DE:S:::::ETDRS
Hmu1224         FE::::R::T:::::P::::
hla1291         :D:::V:::D:RI:::::::
HQ2966A         :YAT:S::::PRI:::::::
HVO_2793        :::E:ST::VLEL:::::::
Hbo2527         :N:::E:::EP:L:::EE::