[R] (-) COG0727 Predicted Fe-S-cluster oxidoreductase 9 genomes BUD0646 9 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG0289 rrnAC1809 HVO_0770 Hbo0761 Hmu0654 Hut0561 hla2737 NP1134A HQ1171A

Pairwise sequence scores
Consensus score	1721	Hut0561	HQ1171A	NP1134A	Hmu0654	hla2737	HVO_0770	Hbo0761	rrnAC1809	VNG0289
1229	Hut0561	1708	1073	1128	1066	1112	1139	1146	727	1098
1291	HQ1171A	1073	2476	1271	1159	1124	1175	1176	797	1222
1359	NP1134A	1128	1271	1770	1188	1186	1168	1213	861	1247
1323	Hmu0654	1066	1159	1188	1780	1229	1179	1243	874	1194
1406	hla2737	1112	1124	1186	1229	1933	1218	1311	872	1185
1419	HVO_0770	1139	1175	1168	1179	1218	1815	1353	891	1247
1500	Hbo0761	1146	1176	1213	1243	1311	1353	1935	924	1258
1011	rrnAC1809	727	797	861	874	872	891	924	1159	919
1381	VNG0289	1098	1222	1247	1194	1185	1247	1258	919	1721

353 symbols
consensus       -----------------QDLEAELERARDLDVAELADAIESIGFECTRCGACCTGHAPAD
#oth            111111111111222235313331431341225421111131111111114113355544
Hut0561         :::::::::::::::::M::::::AA::A::::AI:::::::::::::::H::R:TDE::
HQ1171A         MKDAEMNELSDSEQEEV:S:::::A::KS:S:KS::::::::::::::::::::A:HSGE
NP1134A         ::::::::::::::::MES:::A:G::ES:S:D:::::::::::::::::G:::AIDDEA
Hmu0654         :::::::::::::::::VT:ASD:::::E:::G:::::::A:::::::::E:::ATE::V
hla2737         ::::::::::::::::MES:::::DG:::::PG:::::::::::::::::G::::Y::DE
HVO_0770        :::::::::::::::::M::D:::D:::::::S::::::::::::::::::::K:YEGD:
Hbo0761         ::::::::::::VSHAGPT::D::::::::S::::::::::::::::::::::K::G:::
rrnAC1809       :::::::::::::::::-------------------------------------------
VNG0289         ::::::::::::::::M:::::::::::E::::T::::::T::::::::::::KSE:D--

consensus       ------------------------------------------------------------
#oth            222333223332323411111111111111111111111111111111111111111111
Hut0561         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
HQ1171A         NNDEKTENAHEDETEPAHTQINNRSKTEAPAATAPTENGRVSHNNGSDDQTRTVSNQDNK
NP1134A         ::::::::::::::GT::::::::::::::::::::::::::::::::::::::::::::
Hmu0654         ::DPADEEDTAESAEN::::::::::::::::::::::::::::::::::::::::::::
hla2737         PGGAPAGEGADDPADR::::::::::::::::::::::::::::::::::::::::::::
HVO_0770        ::::::::::::::GP::::::::::::::::::::::::::::::::::::::::::::
Hbo0761         ::::::::::::::DR::::::::::::::::::::::::::::::::::::::::::::
rrnAC1809       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
VNG0289         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::

consensus       ----------------EPHTATVFPDEVRALQDAAE--------------YDWRDVARPM
#oth            11111111111111112111112111121533344365421223211113422113111.
Hut0561         ::::::::::::::::--:::::::::I:TI::GD:::::::::::::::::::::::::
HQ1171A         ANTDVAMESVSTSTST:::::::::::::E::AT:DNMRDGTADTDAHSPTE::::::::
NP1134A         :::::::::::::::::::::::::::::Q::A::DERF::::ET::::S::::::::::
Hmu0654         ::::::::::::::::::::::I::::I:Q:R:DG-::::::::::::::R:F::I::::
hla2737         :::::::::::::::::::::::::::::EVV::::VQF::::GE::::S:::::A::::
HVO_0770        ::::::::::::::::::::::::::::::::E:GGDDSKGESGT::::PME::::::::
Hbo0761         ::::::::::::::::::::::::::::::V:::T:TES:::::::::::::::::::::
rrnAC1809       ::::::::::::::::--------------------::::::::::::::---------:
VNG0289         ::::::::::::::::D::::::::::::DV:A::GAET::::::::::DR:::::::::

consensus       PYGLDEGDDG-PEGETFEWALQTDACGDCTFY----EDDDGTGACTVHEDRPLICQTYPF
#oth            .1..413311242.1......1113....2..111333431412.22134...1.3....
Hut0561         :F::T:P:::PAT::::::::A::::::::::::::-:RE:EA-:SIY:R:::::R::::
HQ1171A         :::::D--EN:ST:T::::::::::::::V:::::::EA::V:S:QA:DN:::::A::::
NP1134A         ::::::--:::-T::::::::::::::::::::::E:A:::::::::::::::V::::::
Hmu0654         ::::S:TA:::V::::::::::::G:::::::::::AEE::V:S::::::::::::::::
hla2737         :F::S:::::E:A::::::::A::D::::::::::::ETG:Q::::::DA::::::::::
HVO_0770        ::::V::::::::::::::::::T:::::R:::::EG::S:R:::Q:::::::::E::::
Hbo0761         ::::T::::::::::::::::::::::::V::EESEGA:GT::::SI:S::::::E::::
rrnAC1809       ::::AD:PE:::::::::::::::D::::::::::A:G::::::::::G:::::::::::
VNG0289         ::::::--:::-A:::::::::A:S::::::::::R:::::::::S::GS::::::::::

consensus       SVALGGT----SQPMGEAV---------------DEEGAVRAHECEGLGRDISREDAEEL
#oth            .1.1221111122....1.111111111111111.3114.1...........3.12.12.
Hut0561         :L:IEDDGAEL:A::::V:::::::::::::::::R::::Q:::::::::::::A::I::
HQ1171A         :::::::::::::::::::::::::::::::::::TA:M:::::::::::::T::A::::
NP1134A         :L:::::::::GE::::::::::::::::::::::R::L:::::::::::::D::T::::
Hmu0654         ::::DN:::::V::::::::::::::::::::::::A:L:::::::::::::E:::::K:
hla2737         ::::D::::::::::::::::::::::::::::::A::::::::::::::::::::::A:
HVO_0770        ::::::::::::::::::::::::::::::::::::::V:::::::::::::::A:::::
Hbo0761         :::::::::::::::::::DSVALGDQQDPDETD::AMT:::::::::::::::::::::
rrnAC1809       ::::::::::::::::::::::::::::::::::::::V:::::::::::::::A:::::
VNG0289         ::::::::::::::::::::::::::::::::::::A:M:::::::::::::::A:::::

consensus       AAALKERAVRELEEAIGVRDAYEPV--EPDAGEVVVHDSEGAKRPDGTPID--
#oth            .31.13.11.1.3..141116.313116455143..2....2.21..124542
Hut0561         :ET::R::::::Q:::::::N:::T::--:IDGI:::::::Q::::::R:RE:
HQ1171A         ::T:RT::I:::::::SL::::::-::PGNTDGI::::::::::::::A::N:
NP1134A         :ET::::SI:D:::::EL:ER:::-::R:::DGA:::::::S:::::::L:RR
Hmu0654         ::T:::::I:::::::A:::S:::::::RAD:::::Y::::::::::::R-::
hla2737         ::::::::::::::::::::G:D:TAG:RSD:D:::F::::::AA::::::GD
HVO_0770        :R::::::::::R::R::T::::S::::TGP:::::::::::::::::RVQ::
Hbo0761         ::::::::::::::::::::E::::::QTES::::::::::::N::::::EE:
rrnAC1809       ::::::::::::T:::::::T:R::::D:S::Q::::::::::::::S:YE::
VNG0289         :G:::A::I:::::::D::E::A:A::N:EP:AT:::::::::::::SAYPN: