9 genomes BUD0667 9 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG1895 rrnAC3398 HVO_2368 Hbo2067 Hmu2208 Hut2076 hla1274 NP3214A HQ3069A

Pairwise sequence scores
Consensus score	858	Hmu2208	Hut2076	NP3214A	VNG1895	rrnAC3398	hla1274	HQ3069A	HVO_2368	Hbo2067
637	Hmu2208	890	511	566	589	566	566	527	571	551
592	Hut2076	511	891	512	569	546	547	482	529	553
609	NP3214A	566	512	882	548	614	536	497	520	532
665	VNG1895	589	569	548	882	640	625	524	578	594
629	rrnAC3398	566	546	614	640	847	569	524	542	561
703	hla1274	566	547	536	625	569	851	597	635	649
635	HQ3069A	527	482	497	524	524	597	931	618	647
705	HVO_2368	571	529	520	578	542	635	618	1058	740
725	Hbo2067	551	553	532	594	561	649	647	740	862

140 symbols
consensus       MLLVRGSAGGTALTGTIYERGEEAPSYKGAPDEDAPYVWVCDEFYEVESGGSEQTIDGRE
#oth            .2211.511..31...21.21132.314.1..331.1..1..2..1.11..432522133
Hmu2208         ::::H:A::::::::::::D::D::EFA:S::D::::::I:::::::DT:::T:::G:E:
Hut2076         :R:I::R:::::::::L::P:::S:::E::::A:::F:::::A::A:::::TV:HV::KD
NP3214A         ::Q:::::H:::::::L::PDD:P:TFS::::DN::::::::A::::::::RT::LGD:T
VNG1895         ::::::::::::::::L:::::T:::F::::::A:::::::::::::D:::QV:RV::ED
rrnAC3398       :::I::T:::::V:::L::P:::P:EF::::::GT:::::::A::::::::QV:S:GD::
hla1274         :I:::::G:::E::::VF:::::P:A::::::::::::::::S:::::::::ALLV::E:
HQ3069A         :IF:::LG:::G:::::F::::D:::::::::G::::::::::::::::::I:T::NDTS
HVO_2368        ::::::RG:::::::::F::::Q::T:R:::::::::::::::::::::::::TE::::T
Hbo2067         ::::::HG:::T:::::F:::::::::::::::::::::::::::::::::::TE::::T

consensus       IRVAFESPMPRGFDTRDQALDAAKEHVRTQFARLGVDASTVRIE---VVREEPAAT----
#oth            231..12.2....31.12.23..32.....12.2.22424.212111.443346665221
Hmu2208         :QI::::::::::QD:E:::::::D::::::V:::I::DE:E:T::::T::SDPEHAE::
Hut2076         :N::::::A::::AD::R:IA::E:::::::G:::LAE:A:E::HET::S:HST:DQ:::
NP3214A         LQ::::::::::::D:EA:::::AD::::::::::::R:::D::::::IEA::QPE::::
VNG1895         VH:::::::::::E:::A::E::R:::::::::I:::PE::DVT:::::Q:HE:DAEF::
rrnAC3398       ::I::::::::::E:::A:I::::::::::::::::AGE::DVT::::QQA:T:--::::
hla1274         ::::::E:::::::::::::S::::::::::::I:::P:G:EV:::::TK:D::--::::
HQ3069A         ::I::::::::::E:::::VE:::A:::::L::I::PR:D:::K::::F:SD:DTGHETE
HVO_2368        :::::DT:L:::::::E:::S::::::::::::V::P:DE::V:::::::P:EEG:PEAE
Hbo2067         :N:::D::::::::::E::VE::::::::::::V::A:ED:::::::::KS::G::::::

consensus       --------------------
#oth            22221111111111111111
Hmu2208         ::::::::::::::::::::
Hut2076         ::::::::::::::::::::
NP3214A         ::::::::::::::::::::
VNG1895         ::::::::::::::::::::
rrnAC3398       ::::::::::::::::::::
hla1274         ::::::::::::::::::::
HQ3069A         LERT::::::::::::::::
HVO_2368        QPVPTDRSADEGSPEGDASH
Hbo2067         ::::::::::::::::::::