9 genomes BUD0668 9 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG1820 rrnAC3481 HVO_2642 Hbo2200 Hmu2469 Hut1115 hla1425 NP4818A HQ3025A

Pairwise sequence scores
Consensus score	692	NP4818A	VNG1820	hla1425	HVO_2642	Hbo2200	HQ3025A	Hut1115	rrnAC3481	Hmu2469
356	NP4818A	880	202	262	298	238	211	194	247	306
268	VNG1820	202	594	218	156	156	137	193	213	175
358	hla1425	262	218	833	362	364	278	185	237	245
444	HVO_2642	298	156	362	796	399	326	193	264	289
399	Hbo2200	238	156	364	399	791	358	150	252	250
340	HQ3025A	211	137	278	326	358	607	187	209	202
313	Hut1115	194	193	185	193	150	187	619	312	264
408	rrnAC3481	247	213	237	264	252	209	312	789	407
408	Hmu2469	306	175	245	289	250	202	264	407	759

136 symbols
consensus       --SD-D---------DGYVHRPD---------------EEPGHDDDG------E-E----
#oth            222332122222254533325151111111111111115454642544332342323422
NP4818A         ::--:-:::::::MS:::R:D::AFDEEGDRIVESDIE:SR::GGS:GDDVSG:HPDAVE
VNG1820         ::--:-:::::::::MVQT:E:Q::::::::::::::::AA:T::--::::::-:-::::
hla1425         VS:EA::GDARESTDG::::V:S::::::::::::::::GG:S:GADPAVSVS:P:AD::
HVO_2642        VS::TTAREDATAES:T:::::-:::::::::::::::DGVAVGG:::::::S:P:AT::
Hbo2200         VN:ED::::::::ETS::::::G:::::::::::::::SGA::KSTR:::::D:P:PA::
HQ3025A         MNT:T-:::::::::--------:::::::::::::::::QTQS:V-::::::-:-::::
Hut1115         ::--:-:::::::::--M:DS:E:::::::::::::::RT:PET:S-::::::-:-::::
rrnAC3481       ::-MA::::::::DES::::::::::::::::::::::T::QAT:TSRAESETGT:AVDG
Hmu2469         MS::D::::::::GDA::::::S:::::::::::::::G::PTSG::ER::::-:-::::

consensus       -GFGRRGWTLVGALALCFLVIPGAIYLLPS---LIASFGLPLRDAYLVLPLVPAVALGLV
#oth            2312442.5121424414232.3422351312256433.2323322.32.12..43..33
NP4818A         RE:DW::::::A:IFVA:::V:TI:::Y:R:::FPTL:::SFL:::::::M:::LV::VL
VNG1820         :MSK:SQ:L::A:::V:G:AA:AF::WAGA:::--G::::GF::T::TI:MI:::L::V:
hla1425         :::::K::A:TAV:FT:V:::::I::VY:Y:::AAGAL:FSFFAT::A:::I:::L::A:
HVO_2642        ::::S:::V:::VV::::::::::V::V::::::P:MA:::YLA:M:A::ML::L:::::
Hbo2200         ::::TK::G::AV:V::T:::::V:::D:::::VF::V:I:YNI:L:::::L::GV:::T
HQ3025A         ::::IH::::::S:L::LII:::I::IQ:::::IL:AV:I:YLVSL:I::::::A::::I
Hut1115         :S::S--:LVL::::IALV:::WSLIV:::ARG::GLV:FS:::::::V::::::G:::L
rrnAC3481       PE::TS::I:::MIGVA::LV::::L:::AAQGV:S::::T::::::T::::::F:::AL
Hmu2469         :E:DW:::::::TVLFA:I:A:::LL:::AAQSFVQ:L::T::::::::::L::FL::S:

consensus       AVWSATRATRG-----
#oth            1..2232333544111
NP4818A         :::AT::P---:::::
VNG1820         G::T:V:G---:::::
hla1425         ::::M:A:::DQ::::
HVO_2642        ::::M:A::::DE:::
Hbo2200         ::::M:G::N:TPDED
HQ3025A         ::::M:A::NETD:::
Hut1115         G::T:L:SR:SQ::::
rrnAC3481       :::::V:SQSK:::::
Hmu2469         :::::M::RS:GA:::