[C] (FrdB) COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit 9 genomes BUD0674 9 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG1308 rrnAC1093 HVO_2809 Hbo2547 Hmu1787 Hut0489 hla1263 NP4266A HQ2995A

Pairwise sequence scores
Consensus score	2283	Hut0489	VNG1308	NP4266A	rrnAC1093	Hmu1787	hla1263	HQ2995A	HVO_2809	Hbo2547
1805	Hut0489	2420	1716	1634	1682	1698	1654	1570	1655	1728
1851	VNG1308	1716	2309	1752	1713	1719	1710	1662	1675	1748
1916	NP4266A	1634	1752	2257	1775	1769	1816	1654	1799	1839
1965	rrnAC1093	1682	1713	1775	2323	1971	1835	1738	1764	1850
1966	Hmu1787	1698	1719	1769	1971	2310	1792	1687	1762	1786
1972	hla1263	1654	1710	1816	1835	1792	2304	1741	1832	1878
1866	HQ2995A	1570	1662	1654	1738	1687	1741	2305	1770	1872
1965	HVO_2809	1655	1675	1799	1764	1762	1832	1770	2299	1962
2053	Hbo2547	1728	1748	1839	1850	1786	1878	1872	1962	2292

314 symbols
consensus       MSTQ-----------VPEQETEEETDTEAEP-------SAGQQRRLAEKRERAEERERQA
#oth            ...311111111111552233133344342331211111534221553334523544435
Hut0489         :::DSNAETGTDAESTA:TDV:SG::AD:::AVPEPDI:SH::::MD::::GMA::DA::
VNG1308         :::K:::::::::::PSQS:::T:::::PAT:::::::TGH:::::DD::A::DD:DEA:
NP4266A         ::::::::::::::::T:::Q:T:PEQT---::::::::EH:E:::S::::::DMS::AK
rrnAC1093       :::::::::::::::IEQ::::T:A:E:T::EVE:::::P:DR::AQRDERQ:Q:QAQRE
Hmu1787         :::I:::::::::::EQ:T::::T::ES:::TVE:::::P:ER::-:::Q:::QA::D:R
hla1263         :::::::::::::::T:T:-:::S:E:D::TEVP:::::K:DE::EEKR:RA::::T:RQ
HQ2995A         :::::::::::::::L:Q:TED:T:TS:V:KE:::::::SPP:AP:TDPLSEI:TDTEHD
HVO_2809        ::::::::::::::::::T-V:::SA:::A-::::::::::K:K:D:K::::::RVQE:R
Hbo2547         :::::::::::::::::::-V:D:SSADT:T:::::::::A::A:MEK::QK::::::::

consensus       AEEEEE----DEETYELKVFRYDPEVEGKQEPRFDDFHVPFHKGMTVLDALIYARDHYDS
#oth            4432665112321.35111......122.31....1.41.132...1....121..31..
Hut0489         :AAA:T:::::G::TH:RI::::::::::S:::::::Q::YEQ::::::::::::::F::
VNG1308         :QA:T:F::::G::V::::::::::IA::E:::::T:T:::ET:::::::::F:::S:::
NP4266A         SDLSD-::::AD::VQI::::::::::::KD::::T:EI::T:::::::::::::::F::
rrnAC1093       V:::TLD::::DD:IT:::::::::::::::::::::R::::::::I:::::::::::::
Hmu1787         VD::IDH:::S:::IT:::::::::::::E:::::::T:::::::::::::::S::::::
hla1263         :::A:KAA:A::::V::::::::::I:::::::::T:::::T:::::::::M:S::T:::
HQ2995A         DSH:--::::::D::V:::::::::IAA::::::::::::Y::::::::::M::::N:::
HVO_2809        EA:AA:KARSADD::H::::::::::PE::::::::::::YKQ:::I::::MW:::::::
Hbo2547         E:A:SAAA::G:D::L::::::::::A:::::::::::::Y::::::::::M::::::::

consensus       SLTFRHSCRQAVCGSDALFVNGSQRLGCKTQISDLEE-PVRIEPLPHQEVVKDLVVDMEH
#oth            1.......1.11.....2.1..4.2.2.1..241124111.1.....21.1.....112.
Hut0489         T:::::::Q:G:::::::::::::Y::::::LNEFD::::::::::::D:::::::::Q:
VNG1308         :::::::::::::::::F::::::::::Q:::E:::W::::V:::::SD:::::::E:D:
NP4266A         T::::::::::I::::::::::A::::::::MV:::W::::::::::A::::::::::::
rrnAC1093       ::::::::::::::::::::::R::::::::::E::D:::::::::::::::::::::::
Hmu1787         :::::::::::::::::::I::R:::A:::::A::DAGTI::::::::::::::::::::
hla1263         :::::::::::::::::M::::G:K:A:::::A:::Q::I:V:::::A::E::::::L::
HQ2995A         :::::::::::I:::::M::::K:::C::::L:::::::::V::::::D:::::::::::
HVO_2809        :::::::::::I:::::::::::::::::::L:::S:::I:V:::::SD:::::::::::
Hbo2547         :::::::::::I:::::::::::::::::::L::::::::::::::::::::::::::::

consensus       FYDQMESVEPYFQTDELPDGELEEQRQTRENREKIKMSTRCIWCGACMSSCNIAAGDNEY
#oth            ..1..11.1.1.22122.112.1....2.1...11.1.....1.1..1....1...1.2.
Hut0489         ::E::DA:::::EP::::ED::::::::::::::::L:::::Q::::A::::V:::::K:
VNG1308         ::::::::D:F:DP:D:::::::::::S:Q:::N::L:::::::::::::::::::::K:
NP4266A         ::::::::::::::N:::::D:::::::::::::V:::::::::S:::::::::::::::
rrnAC1093       ::::::A:::::DA::T::DK:::::::::::::V:::::::::::::::::::::::::
Hmu1787         ::::::A:::::DA:::::D:::::::D::::::::::::::::::::::::::::::::
hla1263         ::::::A:::::::N:Y:::::::::::::::::::::::::::S:::::::::::::::
HQ2995A         :::::::::::::::D::E::::::::S:Q::::V:::::::::::::::::V:::N:D:
HVO_2809        ::::::::::::::NS::::::D:::::::::::V:::::::::S:::::::::::::::
Hbo2547         ::::::::::::::ND::::::::::::::::::::::::::::::::::::::::::K:

consensus       LGPAAINKAYRFAMDEREGEEMKQERLEIIEQEHGVWRCQTQFSCTEVCPKDIPLTEHIQ
#oth            .....1......3..2...333113.12.2.2.1............1.............
Hut0489         :::::L::::::I::::::G:RRE:::::V:D::::::::::::::::::::::::::::
VNG1308         ::::::::::::Y::D:::S:KR:::::::::::::::::::::::D:::::::::::::
NP4266A         :::::::::::::::K::::::::H::N::::::::::::::::::::::::::::::::
rrnAC1093       ::::::::::::::::::::NR:::::R::::::::::::::::::::::::::::::::
Hmu1787         ::::::::::::::::::::QR:::::R::::::::::::::::::::::::::::::::
hla1263         :::::::::::::::::::::I::K:::::::::::::::::::::::::::::::::::
HQ2995A         ::::::::::::T::::::D:::::::::::R:N::::::::::::D:::::::::::::
HVO_2809        ::::::::::::::::::::D:::R::::L::::::::::::::::::::::::::::::
Hbo2547         ::::::::::::T:::::::D:::H:M::L::::::::::::::::::::::::::::::

consensus       ELKREAVKNNLKFW
#oth            ......1.111...
Hut0489         ::::::I:EDI:::
VNG1308         ::::::::E:::::
NP4266A         ::::::::::::::
rrnAC1093       ::::::::::::::
Hmu1787         ::::::::::::::
hla1263         ::::::::::::::
HQ2995A         ::::::::::::::
HVO_2809        ::::::I:::::::
Hbo2547         ::::::::::::::