9 genomes BUD0684 9 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG1916 rrnAC3300 HVO_2218 Hbo1929 Hmu2273 Hut2467 hla1366 NP3176A HQ3124A

Pairwise sequence scores
Consensus score	908	Hmu2273	rrnAC3300	VNG1916	NP3176A	Hut2467	HQ3124A	hla1366	Hbo1929	HVO_2218
726	Hmu2273	896	657	617	640	605	646	624	632	633
721	rrnAC3300	657	899	660	685	648	616	614	635	639
692	VNG1916	617	660	900	680	621	614	576	630	624
719	NP3176A	640	685	680	881	621	605	604	645	603
709	Hut2467	605	648	621	621	928	630	660	617	650
764	HQ3124A	646	616	614	605	630	990	721	708	690
731	hla1366	624	614	576	604	660	721	913	695	672
748	Hbo1929	632	635	630	645	617	708	695	919	688
745	HVO_2218	633	639	624	603	650	690	672	688	900

127 symbols
consensus       -------------MDDADDPVDPSDIGED-DAPPVEEKPYKIIFEANKCFGAGKCAEVSD
#oth            11111111123335435246241.23.46221..1221....1....1.11..1..1224
Hmu2273         ::::::::::::::A:E:A:::::QM:GT:::::::D::::::::::::I:::::::::H
rrnAC3300       ::::::::::::::A::::H::::EF::Q::G:::::::::::::::::::::::::K:R
VNG1916         ::::::::::::::S:::TAP:::::::T:::::I:DA::::::::::::::::::A::A
NP3176A         :::::::::::::--MP:E:::::::::G:::::::AA:::::::::::IA::::::::A
Hut2467         :::::::::::MSE::DE:I:Q:::V:G:::G::::A::::::::::R::::::::AE:P
HQ3124A         MSDTNTSTNDNDND::T::SLSA::V:SSA:::::A:::::::::::::::::R::::A:
hla1366         :::::::::MSDEA:AD:EVLRA::::G-:EG::I:::::::V:::::::::::::::G:
Hbo1929         ::::::::::MSESEES:G:LR::EV:DEAN::::D::::::::::::::::::::::A:
HVO_2218        ::::::::::::::SEES:RPK:::F:T:EN::::::::::::::::::::::R::::A:

consensus       NWEMDIDTGLAKPKSYFFGEDELDENIRAAEVCPAKKDRGVIHVVDRRTDEEIAPDPHGD
#oth            1.311241.2.41541121.11122213..12.....23.1..11...21..21...4..
Hmu2273         ::DLNL:::I:A::M::V::::V:DE::::::::::::V::::::::::::::::::E::
rrnAC3300       ::TL:L:::I:::EA::ID:SD::H::A:::A::::::::I:::I::::N:::::::N::
VNG1916         ::::::G::::D:VA:::D::D:QH::D::DA:::::GD:::::::::S::::::::S::
NP3176A         :::::::::I:::DV:::D:SD:EH::E:::A::::::::::::::::::::L::::K::
Hut2467         D::L:LE::::::ST:Y::::D::HHV::::S:::::G::::::I:::::::::::::::
HQ3124A         ::::::AS:::N:::F:I::::::::::::::::::::A::::I::::::::V:::::::
hla1366         ::V::VQS:M:::R::YI:::::::::::::::::::E::::::::::::::::::::::
Hbo1929         ::::::AS:::R::::Y:D::::E::V:::::::::::::::::I:::A::::S:::N::
HVO_2218        :::::LE::::RA::::V::::::::VE:::::::::G::::::I:::::::LS::::::

consensus       GTLSVDW
#oth            .2.....
Hmu2273         :::::::
rrnAC3300       :S:::::
VNG1916         :S:::::
NP3176A         :::::::
Hut2467         :R:::::
HQ3124A         :::::::
hla1366         :::::::
Hbo1929         :::::::
HVO_2218        :::::::