9 genomes BUD0687 9 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG1289 rrnAC1179 HVO_1248 Hbo0297 Hmu1468 Hut1217 hla2383 NP3526A HQ1807A

Pairwise sequence scores
Consensus score	501	Hbo0297	HVO_1248	NP3526A	HQ1807A	Hut1217	VNG1289	hla2383	rrnAC1179	Hmu1468
348	Hbo0297	520	390	309	344	321	293	309	287	289
380	HVO_1248	390	518	308	328	352	302	332	307	314
354	NP3526A	309	308	470	284	307	323	334	320	309
357	HQ1807A	344	328	284	540	305	290	361	338	347
425	Hut1217	321	352	307	305	627	324	356	369	367
383	VNG1289	293	302	323	290	324	535	347	349	357
397	hla2383	309	332	334	361	356	347	466	367	378
413	rrnAC1179	287	307	320	338	369	349	367	465	415
420	Hmu1468	289	314	309	347	367	357	378	415	453

83 symbols
consensus       MAFEEDDTVVLHDKHSEYDGETGTITQVVETMFGDATYTVSFEDGQEQGIPEDALEAA--
#oth            .2.11215.12111..11..22.211114.1...141.112.11...4.123.3.12111
Hbo0297         :E:D:G:A:::N:::::F::QV:K:::::::::::E::V:::DE:::V::SP:Q:D::::
HVO_1248        :S::K::K:::N:::::F::::::V:::I:S:::EP:::I::DE:::V::AQ:Q::::::
NP3526A         ::::KG:R::F:::::D::::::EVA::S::::::K::V:D::E:::G::A:::::::::
HQ1807A         :E:D:::S:::::::::F::K:::V::::::::::::::::::::::V::AA:Q:DPV::
Hut1217         ::::::E:::M::E:::::::V::V:R:M:::::::::::Q:DE:::::V::::::::PD
VNG1289         :S::KG::::::E:::D::::E:E:::TA::::::VN::I:::::::A:V:::S:DLV::
hla2383         :S::KE:E::::::::::::::::::::M::::::::::::::::::T:V:::::D:V::
rrnAC1179       :::::::S:I:::E::D::::E::::::::::::::N::::::::::::V:::N::::::
Hmu1468         :::::::::::::::::::::E::::::::::::::N::I:::::::::::::S:::V::

consensus       ---------EDDD--EAD-E---
#oth            11111112224234322242222
Hbo0297         ::::::::::G:EAD:::D::::
HVO_1248        :::::::::DG::AD:::E::::
NP3526A         ::::::::::::E::---:-:::
HQ1807A         ::::::::::TEANTDENNTASE
Hut1217         EEVSSTESDDEE:VA:::D:SDN
VNG1289         :::::::AEA:::DA:::A::::
hla2383         ::::::::::SEE::---:-:::
rrnAC1179       :::::::::::E-::---:-:::
Hmu1468         ::::::::::E--::---:-:::