[K] (TFA1) COG1675 Transcription initiation factor IIE, alpha subunit 9 genomes BUD0729 9 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG0757 rrnAC0861 HVO_1174 Hbo0385 Hmu1534 Hut0974 hla1561 NP4106A HQ2491A

Pairwise sequence scores
Consensus score	1360	Hut0974	VNG0757	NP4106A	rrnAC0861	Hmu1534	hla1561	HQ2491A	HVO_1174	Hbo0385
1108	Hut0974	1356	1038	1045	1126	1083	1067	1023	1013	1007
1103	VNG0757	1038	1394	1063	1086	1091	1085	988	1004	1033
1167	NP4106A	1045	1063	1359	1116	1134	1092	1016	1052	1065
1186	rrnAC0861	1126	1086	1116	1366	1180	1108	1035	1057	1055
1170	Hmu1534	1083	1091	1134	1180	1393	1114	1016	1070	1072
1226	hla1561	1067	1085	1092	1108	1114	1878	1094	1125	1135
1143	HQ2491A	1023	988	1016	1035	1016	1094	1348	1188	1222
1217	HVO_1174	1013	1004	1052	1057	1070	1125	1188	1360	1259
1208	Hbo0385	1007	1033	1065	1055	1072	1135	1222	1259	1341

251 symbols
consensus       ------------------------------------------------------------
#oth            111111111111111111111111111111111111111111111111111111111111
Hut0974         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
VNG0757         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP4106A         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
rrnAC0861       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
Hmu1534         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
hla1561         MTRSFSSITQTILVAFSLKMAIDSKRSRSGATAGRRGAEKGIGLGKGGQPQLRSAVTVSS
HQ2491A         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
HVO_1174        ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
Hbo0385         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::

consensus       ------------MAFEDLLNDPVIQKYLHELVGPTGMPVAAAPPDGEVTDEELAEELGLE
#oth            111222222222...121.2...1..........1....................1.1..
Hut0974         ::::::::::::::::EY:E::::::::::::::::::::::::::::::::::::::::
VNG0757         :::MALRPPVST:::::::D:::V::::::::::K::::::::::::::::::::R::::
NP4106A         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
rrnAC0861       ::::::::::::::::E::E::::::::::::::K:::::::::::::::::::::::::
Hmu1534         :::::::::::::::::::E::::::::::::::K:::::::::::::::::::::::::
hla1561         GAFNPVLYQIHV::::::::::::::::::::::::::::::::::::::::::::::::
HQ2491A         :::::::::::::::DE:::::::::::::::::::::::::::::::::::::::::::
HVO_1174        ::::::::::::::::E::::::::::::::::::::::::::::::::::::::::R::
Hbo0385         ::::::::::::::::G:::::::::::::::::::::::::::::::::::::::::::

consensus       LNDVRRALFILYENDLASYRRVRDEDSGWLTYLWTFHYENIPENLEEEMHRLLDALEERR
#oth            .................1...1..............3.111.12.21..21.111.12.2
Hut0974         :::::::::::::::::::::L::::::::::::::E:D::::Q::S:::D:FEG:::::
VNG0757         :::::::::::::::::T::::::::::::::::::Q:::V:G::R:::D:::E::VD::
NP4106A         :::::::::::::::::::::L::::::::::::::Q::::::Q:::::::::E:::N::
rrnAC0861       :::::::::::::::::T:::L::::::::::::::Q::K:::Q:Q::::::::G:::::
Hmu1534         :::::::::::::::::::::L::::::::::::::K::::::K:::::::::::::D:E
hla1561         :::::::::::::::::T::::::::::::::::::::D::::::::::Y:::::::::E
HQ2491A         :::::::::::::::::T:::::::::::::::::::::::::::QS::Y:::::::::L
HVO_1174        :::::::::::::::::::::::::::::::::::::::::::::::::Y:::::::::L
Hbo0385         :::::::::::::::::::::::::::::::::::::::::::::::::Y:::::::::L

consensus       EYEREHEFYLCEPCGIRFEFGEAMEFGFECPECGAQLEAMENDRLVDAMERRIEELRDEL
#oth            3..241....115121....31..13..1..11.441.311.23123..241224.22..
Hut0974         :::LD:::::::N:::::::AD::DY:::::D::SS::::::TA:IT::DE::D::ES::
VNG0757         :::L:N::::::V:S:::::::::DL::::::::SAV:::::TD:::::DD:::R::S::
NP4106A         Q::S:N:::::GE:QL::::D:::::::::::::GR::S:::::::N:::QH::A:::::
rrnAC0861       :::::N::::::H:::::::::::::::::::::N:V:T:::T:::T:::N:L:::::::
Hmu1534         S:::DN::::::R:::::::D:::::::Q:::::D:V:S:::T::::::DE::AK:::::
hla1561         ::::T:::::::V:S:::::::::D:::::::::SPV:::D::::RE::GQ:V:K::N::
HQ2491A         ::::S:::::S::A::::::S::::L::Q:::T::P::PI::QEMIN::::::DS:QS::
HVO_1174        D:::N:::::S::A::::::S::::H::Q:::T:::::P:D::D::::::::::::::::
Hbo0385         ::::T:::::S::A::::::S::::L::Q:::T::P::P::::DM:::::::::::::::

consensus       NVDVTG-----
#oth            22244734111
Hut0974         :L:IDT:::::
VNG0757         A:EA--:::::
NP4106A         H:ETAEA::::
rrnAC0861       :A::DVEA:::
Hmu1534         :::HEREDAEA
hla1561         :::::::::::
HQ2491A         ::G::QTV:::
HVO_1174        ::E:::TN:::
Hbo0385         ::EA:N:::::