9 genomes BUD0739 9 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG2508 rrnAC2971 HVO_2941 Hbo1596 Hmu3202 Hut2382 hla0527 NP0424A HQ1054A

Pairwise sequence scores
Consensus score	810	HQ1054A	hla0527	VNG2508	HVO_2941	Hbo1596	NP0424A	Hut2382	rrnAC2971	Hmu3202
553	HQ1054A	841	441	487	525	569	432	495	487	477
551	hla0527	441	838	533	530	541	511	525	501	496
646	VNG2508	487	533	804	567	584	565	575	557	572
629	HVO_2941	525	530	567	796	674	547	572	558	604
670	Hbo1596	569	541	584	674	803	549	597	597	583
626	NP0424A	432	511	565	547	549	823	619	601	623
709	Hut2382	495	525	575	572	597	619	804	676	700
687	rrnAC2971	487	501	557	558	597	601	676	923	716
698	Hmu3202	477	496	572	604	583	623	700	716	813

133 symbols
consensus       --------------MVR--EDGKRNFALREEDGDEPSVFSGGTPRQAALKAARRLDPAD-
#oth            11111111111111.1111131....111231.41212.1.31..........1.12221
HQ1054A         ::::::::::::::::::::::::::VML-:::EKTRQ:T:RM::::::::::::EGY:G
hla0527         :::::::::::::::::::::::::::::::::S:::E:::NM::::::::::T:E::P:
VNG2508         :::::::::::::::::::::::::::::TD::T:::::::N::::::::::::::DVG:
HVO_2941        ::::::::::::::::::::::::::V::::::T:T:::::SM:::::::::::::::G:
Hbo1596         ::::::::::::::::::::::::::V::::N:T:S:::::SM::::::::::::::V::
NP0424A         :::::::::::::::APDDD:D::::::::QN:::::::::R::::::::::::::::G:
Hut2382         :::::::::::::::A:::DTD::::::::S::N:S::::::::::::::::::::::P:
rrnAC2971       MFCHVLNWHGAVKS:AP::DSD:::::::-:::::S:::::::::::::::::::E::::
Hmu3202         :::::::::::::::A:::DKD:::::::TQ::::T::::::::::::::::::::::::

consensus       --SEDAA--DPEEIRLREKGTDKVHIYEAWAWEEDAP--DDKPD--WMP--GDI---TKG
#oth            121.25.23334311.1.1..411.2131...423..113.21211.121122.111.11
HQ1054A         YN::S::KDN:TK:::L:R:::RI:V:H::::MD:::::S:::E::::E:::E:STV:::
hla0527         ::::EE:::ERITL:::::::Q:::E::G:::KDS::EV::AA:EF:LNDLD:::::::A
VNG2508         :E::SE::::RNR:E::::::::I::::::::::T::::::::::::::::::::::::A
HVO_2941        :::::D:KS:AV::::::::::::::FD::::NSS::::E:::G::::E:::K:::::::
Hbo1596         :::::K:REQAT::::::::::::::FD::::VD::::::::::::::E:::::::::::
NP0424A         :::::N::::ET:L:::::::K:::::QG:::::T::::N:S:::::::::EE:::::EA
Hut2382         ::::::::::::T::::::::E:::V::G:::::::::::::::::::::::E:::::::
rrnAC2971       ::G:EQ:::::::::::::::H::::::::::V:E:::::::::::::::::::::::::
Hmu3202         :::::D:::::::::::::::H::::::G:::::E::::::::G::::::::::::::::

consensus       NVSKQGIEHLEEI
#oth            ....211212132
HQ1054A         :::::E:::::--
hla0527         ::::::::YIDDE
VNG2508         :::::::D:R:T-
HVO_2941        ::::K:::::D:-
Hbo1596         ::::::::::::-
NP0424A         ::::E::Q:::::
Hut2382         ::::::V::::::
rrnAC2971       ::::::V:::D::
Hmu3202         ::::E:V:::D::