[O] (-) COG1370 Prefoldin, molecular chaperone implicated in de novo protein folding, alpha subunit 8 genomes BUD0804 8 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG0421 rrnAC0210 HVO_1105 Hbo0610 Hmu0680 Hut0914 hla2638 NP0352A -

Pairwise sequence scores
Consensus score	1172	Hut0914	hla2638	VNG0421	rrnAC0210	Hmu0680	NP0352A	Hbo0610	HVO_1105
751	Hut0914	1127	632	558	642	608	543	601	593
836	hla2638	632	1335	590	669	640	612	708	626
784	VNG0421	558	590	1198	632	587	637	638	591
843	rrnAC0210	642	669	632	1186	753	601	633	618
839	Hmu0680	608	640	587	753	1218	636	621	661
778	NP0352A	543	612	637	601	636	1150	663	699
841	Hbo0610	601	708	638	633	621	663	1409	705
807	HVO_1105	593	626	591	618	661	699	705	1205

208 symbols
consensus       ---------------------------------MDDAALDDLRTVADYQFGAGAGDALFP
#oth            11111111111111111111111111111122345334554.223.3..1141124...3
Hut0914         :::::::::::::::::::::::::::::::::--MDEWTR:GRI:::::S:::S::::G
hla2638         ::::::::::::::::::::::::::::::::MS:E::FA::::G:::::::::::::::
VNG0421         ::::::::::::::::::::::::::::::::::Q::GIPA:::::A::Y::A::R::::
rrnAC0210       ::::::::::::::::::::::::::::::::::S:DEFRG::RA::::::G:G:T:::A
Hmu0680         ::::::::::::::::::::::::::::::::::SER:T:L:TR::T::::P::DE::::
NP0352A         ::::::::::::::::::::::::::::::::MS:ERDV:A::::::::::R:::E:::-
Hbo0610         MWRRSLRQPQTATDFTPHAKARDMSDEADESSGDG::T:S::::::N::::S:::A::::
HVO_1105        ::::::::::::::::::::::::::::::MTEGHATD:::::V::::::::::::::::

consensus       DDDGLTVTRSSSGRPRQVHADD---------G-RLVSYGTDGRFTLGVAGGRRLLDALDA
#oth            535533232142...1.1434211111111122.2322.3...21.143..4.1633234
Hut0914         :TT:::::::K::::::I::P::::::::::::::::L:L:::::::LT:::::KA::::
hla2638         P:ET::LR:::G::::::IVG:VNDDPGSPE:D::::::::::::::I:::::IR:GFA:
VNG0421         E:KPHH:Q:::T:::Q:I:R::::::::::::A::::V:L:::L:::P:::Q::I:::EH
rrnAC0210       GP:T:D::HT::::::::::T:::::::::::::IAT::D::::R::L:::N:::::F:G
Hmu0680         :V:::D::TTR:::::::RDG::::::::::D:::LE::S::::::::::::::::G::D
NP0352A         -:GEVEIQ:TG::::Q::LV:G:::::::::E::V::::::::V::SAV::K::QT::SP
Hbo0610         -::N:::R::T:::::::L::E::::::::::::I:::::::::::::E::I::VESSSP
HVO_1105        A:ADIELS::R:::::::YVEG:::::::::D::VT::::::::::::::::::Y:D::G

consensus       PRHRVVVGDESEPFVRDGRNAFAKFVTSADPAIRPGDEVLVVHEDGDLLAVGRAELSAAA
#oth            244214..21.1..1.111.1.....2311443.21..221143115121......2133
Hut0914         :TG::Y::E:::::::E::::::::::E:GAS::SD::::I:R::DT::G::::::P:::
hla2638         :C::M:::E:::::::E::::::::::A::DG::::::::::DDEDA:F::::::::G:E
VNG0421         ::A:::::::::::::::K:V::::::DV:DDA:Q:::LA::::::R:::::::::D::S
rrnAC0210       ::::::::::::::I:E:::::::::Q:::S:L:::::A:::::::Y:::::::::PGSG
Hmu0680         A::Q:::::D::::::E:::::::::R:::EG:::::::::::Y:::::G::::::PGE:
NP0352A         :AY::I:::D:::::::EK:V:::::REV::::::::::::E:Y::::::::::::::::
Hbo0610         :SN::T::S:::::::::K:::::::::V::EV::::::A::TP:DVVIG::::::::E:
HVO_1105        DAYV:R:::::V::::::K::::::::D::::V:S::::C::GP:::::G::::::::D:

consensus       MADFETGMAVKVRNGAG---------EE
#oth            151121.1..4..5.2333111122223
Hut0914         :::LAS:V::S::D::-:::::::::::
hla2638         AEH:AS:V:::::::::SEGDGGNGTD:
VNG0421         :R::::::::S::A:VPAT:::::::DA
rrnAC0210       :D:::::::::::Q::-::::::::::D
Hmu0680         :L:::::::::::H:::TA::::DAS:S
NP0352A         ::::::::::A::D:N-:::::::::P:
Hbo0610         :I::::::::F:::::::::::::::::
HVO_1105        :L::Q:::::R::E::D:::::::::::