8 genomes BUD0820 8 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG1183 rrnAC1364 HVO_1120 Hbo3773 Hmu1883 Hut1424 hla1506 NP1544A -

Pairwise sequence scores
Consensus score	695	HVO_1120	Hut1424	Hmu1883	rrnAC1364	NP1544A	Hbo3773	hla1506	VNG1183
324	HVO_1120	855	208	237	222	191	230	179	174
352	Hut1424	208	662	244	291	219	265	191	250
391	Hmu1883	237	244	688	335	219	270	209	260
387	rrnAC1364	222	291	335	792	250	252	240	301
399	NP1544A	191	219	219	250	810	382	322	305
464	Hbo3773	230	265	270	252	382	897	341	345
400	hla1506	179	191	209	240	322	341	1682	348
375	VNG1183	174	250	260	301	305	345	348	649

223 symbols
consensus       ------------------------------------------------------------
#oth            111111111111111111111111111111111111111111111111111111111111
HVO_1120        ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
Hut1424         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
Hmu1883         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
rrnAC1364       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP1544A         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
Hbo3773         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
hla1506         LRPGSYSRAKTSSRIPGDRRPADINARPDPPPDLCAPFGPTPPRVFDLIYRNAIYPCGVR
VNG1183         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::

consensus       ------------------------MVEDDDRRRVVDEPRGAD---------------SRE
#oth            11111111111111111111111224554325466242.5441111111111111112.2
HVO_1120        :::::::::::::::::::::::::DD::P:::----::IDG:::::::::::::::::Q
Hut1424         :::::::::::::::::::::::MTANA:G:PEAI:Q:::R:::::::::::::::::::
Hmu1883         ::::::::::::::::::::::::-MP::PLSVT:::::D:V::::::::::::::::::
rrnAC1364       ::::::::::::::::::::::::---MEEFDHE::A::::T::::::::::::::::::
NP1544A         :::::::::::::::::::::::::::RTE:::ID:GD:APN:::::::::::::::G::
Hbo3773         :::::::::::::::::::::::::::KP::Y::GE:::TV:ERDSSDGRENLGNAVE::
hla1506         TCSGAFRGRENPRNRVRWGMCTPG:::KT::TGGS:GM:S:::::::::::::::::G:R
VNG1183         ::::::::::::::::::::::::--MTA::T::T::::S:T:::::::::::::::G::

consensus       WEVFVREDEADPLRHVGSVSAPSADIAREQARSLFAWYARDLWLCPADAVARYQTGEL-A
#oth            1.1.1.34642112.1.1.2.23414.313.54..2352432.11.23327.24365323
HVO_1120        ::::Y:DVPTE:M::::::::::E:L:T::::T::GGGDA::::A:::EFL:LGGND:A:
Hut1424         :::::::TVE:::::::::T:DEKAT:::::E:::G-DVVTV::::GS:::::PDP:::-
Hmu1883         ::L::::H:S:::T:A::::::::::::::::Q::D:S:EA::::::E::E:C::ERAS:
rrnAC1364       ::::::::T::::T:::::::::V:::::::A::::RT:VT:::::::KTR::::D:T:T
NP1544A         ::L:::S:SE:::::::::R::D::G:Y:L:CR::::::E:V:V::SAD:T::T:T:::T
Hbo3773         ::::::::DD:A:::::::::::::::Y:::TK::G:::N:I:V::::::C::S:HT::D
hla1506         F::::::R:::::::::T:T::TP:A:HGE:SK::::::::V:V::::ETH::SA:S:AD
VNG1183         ::::::A:ADA::K:::::T:GT::T:H:H:S:::D:V::SI:V::::ETQ::T::GV:-

consensus       EDAERVAGD----------------------------------
#oth            5443444543544444533344223332112211111111111
HVO_1120        KGE:STD:TEHGGMEHDGAGDARGAENGVSAE:::::::::::
Hut1424         LPG:::---::::::::::::::::::::::::::::::::::
Hmu1883         VA:TE:DEA::::::::::::::::::::::::::::::::::
rrnAC1364       LGTGKTED:ATMSVDEMESETLRGENR::::::::::::::::
NP1544A         :::PT:TP:AADGEPATGSESR:::::::::::::::::::::
Hbo3773         D::::MTISSKDEERTHEA::::::::::::::::::::::::
hla1506         :ESGEA:::ENPDADEPRVYEETEGTPTVSCGGAPVDDTEGSR
VNG1183         -:GG:S:--::::::::::::::::::::::::::::::::::