[NT] (CheR) COG1352 Methylase of chemotaxis methyl-accepting proteins 8 genomes BUD0846 8 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG0966 rrnAC2206 HVO_1222 Hbo0336 Hmu0404 Hut1636 hla1008 NP2170A -

Pairwise sequence scores
Consensus score	2079	HVO_1222	Hbo0336	VNG0966	hla1008	NP2170A	Hut1636	rrnAC2206	Hmu0404
1311	HVO_1222	2149	1482	800	1030	1005	1106	1083	1113
1277	Hbo0336	1482	2096	856	1069	999	1086	1069	1070
1125	VNG0966	800	856	1766	815	937	931	976	996
1363	hla1008	1030	1069	815	2061	1069	1089	1204	1167
1326	NP2170A	1005	999	937	1069	2093	1212	1176	1116
1630	Hut1636	1106	1086	931	1089	1212	2074	1477	1438
1638	rrnAC2206	1083	1069	976	1204	1176	1477	2060	1603
1641	Hmu0404	1113	1070	996	1167	1116	1438	1603	2068

285 symbols
consensus       ---MSSGSDRGFRELLEYIGDELDFETGFYNDAYLDRRITARMRRRDIDDYREYQRLL-E
#oth            1245565343515622332444351333311221111112111..12412164.432.15
HVO_1222        :MPS:ATD:PA:DR::D::E:S:Q:Q:SS::::::::::S::::::R::::GS:HD:::T
Hbo0336         MARTD:S::PT:::::D:VESS:S:A:SS::::::::::S::::::GVES:D:::S:::D
VNG0966         :::---------------------------------------::::GVEE:AG:LT::E:
hla1008         :::::GE:ETP:EGV:RQ:N:TVP::P:Y::ES::::::::::::::TESHT::E::::R
NP2170A         ::MKGTDT:T::EAVVR:VA:NMA::PDS::ES::::::S:::::T:C:::EG:LDI::A
Hut1636         :MSRR:::P::::S::::::S::::::D::::::::::::::I::T:S::::A:E::::K
rrnAC2206       ::::NK::E:T:ND:V:F::E:M:::S:::::S::::::::::::T:TE::QT:::::::
Hmu0404         :::::Q:DQ:Q:Q::::F::A:M:::S::::::::::::::::::T:::S::::R:Q:::

consensus       RDDDEREALLDALSINVTSFFRNPEVWEALRDVLRELTSDHRR---VRIWSAPCADGREP
#oth            3132.231.112.11...2...1122.22..4.1222235413111133...111....1
HVO_1222        D:EE:QQ:::::::V::::::::::::::::E:::D:S:RGS:HDPIK::::A:S::::A
Hbo0336         G:EE:QT:::N:::V::::::::::::D:::E:IADIA::G:-::::N::::A:S::::A
VNG0966         D:::::AE:::T::V:::E:::DEK::T::::::L::ADTV:S:::ID::::A:::::::
hla1008         E::G:::::M:::T::::E::::::M:D:::G::::R::EQ:::::::V::::S::::::
NP2170A         DSE::Q::::::::::::::::::P:::R:::::AM::EE::T::::NC:::::::::::
Hut1636         ::G::A:::M:S::::::G::::::A::R:::::::::T:::T:::::V:::::::::::
rrnAC2206       ::NG:::E:::S:::::::::::::A::R::P::::::ENN:::::::L::::S::::::
Hmu0404         ::::::A::::S::::::G::::::A::S::S:::D::DQ:::::::NL:::::::::::

consensus       YSLAMLALDDPRIDERRVEILATDINEDILAEARAGVYETSRTTDIADQLEPLSDPERYV
#oth            ..4....3.12421324231211..3311133..2.3.3213.2.1331.3112345421
HVO_1222        :::::::H::D:V::::I::VG:::KRE::RA::::E:RA:E:N:V:E::D:IGRW::F:
Hbo0336         ::M::::H::D:::PNK:K::G:::KPE:IRA::::E:HA:E:N::EE::::::QNN:::
VNG0966         :::::::::-AGL:P:N:S::::::D::A::R::::R::ST::A::S:::GF:DN:QE::
hla1008         ::V::::C:::E:::S:::V:GS::S:EA:DS::E:::H:T::::::EE:::::::D:::
NP2170A         ::I::::R:::N:R::A:::T::::DAEA:::::E::::ST:::::GS:::::::::AH:
Hut1636         :::::::R::AQ:::::LD:::::::P::::::::::::::Q::::EAE::::::VSP:I
rrnAC2206       ::A::::::::E::A:::::T:::::A:::E:::K:T:A::Q::::::E::::D:YTK:I
Hmu0404         ::A::::::::QV:D:S:S::G::::::::R:::E:T::::H::::::E:A::D:YSE:I

consensus       D--RDGD-TFRVRDRVKDMVTFEQHDLIRGDPKRDFDLVLCRNLLIYIDSEYKEPIFETL
#oth            1112121131413251431.4.131..132423341.113...22...1434.51211.2
HVO_1222        :::::D::::::K:A:T:::R::RR::::EE:PGT::::V::::F:::NA:S:RAV::::
Hbo0336         E:::::::IY::T:E::SL:S:RK:::VQER:PDT::::V::::F:::N::A:QA::D::
VNG0966         ::::E::RA:V:N:::::L::::R::::T::::SG::::A:::VC::::KQ::L::LD:V
hla1008         E::::E::A::::SE:QRL:D::A:::::DGARDP::V:::::::::::VDH:GAL:D::
NP2170A         EITD::T:S:A:K:D::R:::::K::::S:R::SGH:::::::::::::KS:::::::::
Hut1636         ::::::::::T:::SIRE::S:::::::::::QGE:::M::::F::::::SF:::::::I
rrnAC2206       E::Q::::::Q:::Q::E:::::::::::::::::::::F:::::::::::F:V:::::I
Hmu0404         ::::::::S::I:K::S:::E:::::::::AS:::::::F:::::::::G:::V:::::I

consensus       EESLREGGYLMIGMTETLPPECRDRFEPVDKRRRIYRRV------
#oth            451.331.3.21.21.12.55323411231224111233233221
HVO_1222        GSA:NPD:::T::::::I::T::QQ:D::E::L::::ASDAAVGR
Hbo0336         GSA:TPD:::T::::::I::S:::::D::E::L::::NAANSNP:
VNG0966         SK::::::H:VL:Q:::::G:VKE:::AE:P:I:::S::ADT:::
hla1008         :A::ADD:V:VL::::SV::DRS::Y::I:::::VF:::::::::
NP2170A         TDA:::::F:T::KS::::RSF::AYD:Y:RGKH::::K::::::
Hut1636         S::::S:::::::::::I:NQ::GT::S:::Q::::T::::::::
rrnAC2206       RG:::::::::::::::::A::::S::A::::H::::::::::::
Hmu0404         :::::::::::::::::::TA:::S::A:::QH::::K:::::::