[S] (-) COG2119 Predicted membrane protein 8 genomes BUD0890 8 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG0535 rrnAC0497 HVO_0820 Hbo0714 Hmu0629 Hut2731 hla1286 - HQ1562A

Pairwise sequence scores
Consensus score	1696	rrnAC0497	Hmu0629	Hut2731	Hbo0714	HQ1562A	hla1286	VNG0535	HVO_0820
727	rrnAC0497	1167	652	678	620	565	563	424	633
1241	Hmu0629	652	1820	1059	1069	1069	1109	446	1060
1238	Hut2731	678	1059	1707	1051	1050	980	467	1012
1334	Hbo0714	620	1069	1051	1743	1235	1155	470	1115
1357	HQ1562A	565	1069	1050	1235	1735	1197	406	1073
1313	hla1286	563	1109	980	1155	1197	1822	453	1115
500	VNG0535	424	446	467	470	406	453	710	491
1289	HVO_0820	633	1060	1012	1115	1073	1115	491	1704

254 symbols
consensus       VTGYLEILVVAFVAQLAVLPGEKVQFIIAGLSTRYDPLVVVAAAGSAFAGWTALEILFGQ
#oth            224341123213341121111111112112111223131112111211121112113213
rrnAC0497       ------------------------------------------------------------
Hmu0629         :::FV::VA::MI:::S::::::::::::::::K:N::::::::::::::::::::A::A
Hut2731         ::E:::::::::GM:::::::::::::::::::::H:::::S:::T::::::::::G::N
Hbo0714         :::::::::I:::Y:::::::::::::::::::::N::::::::::::::::::::::::
HQ1562A         MST:::::II::IT:::::::::::::::::::::::I::::::::::::::::::::::
hla1286         ::A:A::V::::::::::::::::::M::A:::::::K:::::::::::::::I::A:::
VNG0535         ------------------------------------------------------------
HVO_0820        :::WW::::::L:T::::::::::::::::::::F::K:::::::::::I:::::::L::

consensus       ALQAALPPIALDAITAGLFLLFAVLLYRSAPDAN------SPQSAAETDGGVA-------
#oth            123321233313231142143113123112166422321145653453112652212222
rrnAC0497       -----------------M:::::I::L::::A:GAEQQ::E:A:GFT::::QL:::::::
Hmu0629         :I:::::GVY:::F:::M:::::::::::::TTGA:::::Q:EP::IA::DG:GADHRTD
Hut2731         :::N:::E:Y:T:F:::::V:::::MI::::EP:::::::--D:TTK:::::T:::::::
Hbo0714         :IRS:::::::N::::A:::T:::::::::::S:::EP:::H:::T:::::F::::::::
HQ1562A         ::::V::::::NVV::S::::::I:::::::SN:NTNPDV:DTTT::::::L::::::::
hla1286         :::S:::GVV:::V::V::FV::Y:::::M:NRE:::::::G:I:SDG::DPEAVDSDPE
VNG0535         ----------------------------------::::::-------------:::::::
HVO_0820        ::KN::S:A:::::::V::AT::::::::::::S::::::AESE::T:::::S:::::::

consensus       -------ALEAVTLPGPLNRVPGSFGGFLPIFAMMAAGEFGDKTQLVTIGLAAQYGA-TS
#oth            2221124453743242447544442122211141122........11..1..32.1.112
rrnAC0497       :::::::---D:RV:VVDWQ::NKL:::::::::::F:::::::::I::T:::::S:HA:
Hmu0629         GGTATVDLP:V:::A:REFT::DR::S:::::LL::::::::::::I::T:::E:::::A
Hut2731         ::::::ESVGTLDVSVFGYE::ALL::W:::::::::::::::::::::::::D::::::
Hbo0714         ::::::DPADQAD:::::T:LS::::::I:::V::::::::::::M::::::ID::::::
HQ1562A         ::::::::::M::::::::::S::::::::::IL:VT:::::::::::::::V:::::::
hla1286         PSDATLA:::S:::::::D:YA::::::::::VLT:T:::::::::::::::V:::::::
VNG0535         :::::::--------------------------::F::::::::::::::::SD:::::P
HVO_0820        ::::::GLDD:P:VF:RELSTQ:-::::::::::::::::::::::::::::V:::::::

consensus       AIWAGEMLAIIPVSLANAYFFHRFSHRFDLRKAHLGSAALFGFFAADTVLSIAAGFSVWE
#oth            ...5......1.1.22..11.23.112113.211132.4..4..13.331334421.2..
rrnAC0497       :::T::::::::::::::L:::::A:::N:::::FVG:G::L:::::FA::VTM:V:L::
Hmu0629         ::::::::::V::::L:::::YT::::::::::::FG:I:::::GL::::::LT:::I::
Hut2731         :::V::::::::I::L::::::::::MVN:::::F:G::::::::::N::K:V::::L::
Hbo0714         :::F:::::::::::::::L::K::::::M::V::L:::::C::GL::::QMTMNV::::
HQ1562A         :::I::::::::I::::::L::S::G:VNM:T:Y::::L:::::GI:AIM::LFD:::::
hla1286         :::L::::::::I:::::::::T:A::::M:R::::::V::A::G:::::::::::::::
VNG0535         :::L::::::::::MV:::::D:::GK::A:::::V::V::F:::G::L:EVSV:V::::
HVO_0820        ::::::::::::::I::::::::::::::T:::Y::A:G::A::::::L::L:T::::::

consensus       TIVATISAAVLAAV
#oth            24264324423332
rrnAC0497       :M:SS:A:Q:G:--
Hmu0629         :::DALTT:L::V:
Hut2731         E:IT:::SV:::::
Hbo0714         SA:KAVA:GLGV:-
HQ1562A         ::I:E:TT::S:::
hla1286         :FME:V:::ASGLF
VNG0535         EL::LA:QLL----
HVO_0820        :L:G:A:D::::LF