[G] (Fbp) COG0158 Fructose-1,6-bisphosphatase 8 genomes BUD0952 9 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG0684 rrnAC0772 HVO_1446 HVO_2131 Hbo0108 Hmu0950 - hla0825 NP1592A HQ1881A

Pairwise sequence scores
Consensus score	2137	HVO_2131	Hmu0950	rrnAC0772	HQ1881A	HVO_1446	Hbo0108	hla0825	NP1592A	VNG0684
1495	HVO_2131	2201	1088	1141	1248	1314	1321	1161	1225	1122
1397	Hmu0950	1088	2148	1376	1110	1160	1174	1164	1197	1031
1401	rrnAC0772	1141	1376	2187	1105	1186	1202	1108	1272	1099
1526	HQ1881A	1248	1110	1105	2336	1412	1540	1294	1220	1173
1704	HVO_1446	1314	1160	1186	1412	2260	1610	1314	1268	1255
1715	Hbo0108	1321	1174	1202	1540	1610	2256	1368	1327	1256
1570	hla0825	1161	1164	1108	1294	1314	1368	2199	1290	1227
1539	NP1592A	1225	1197	1272	1220	1268	1327	1290	2120	1284
1405	VNG0684	1122	1031	1099	1173	1255	1256	1227	1284	2187

327 symbols
consensus       -----MTDTN-TE-----------------IDAIVDAIAATAPEIRAGLPGRRVYAEDEN
#oth            112343415544244533321111111111246132432411121.612223.454444.
HVO_2131        ::::::::PSSR:DDV::::::::::::::V::::ETLC:A::S:::::::::::E:GT:
Hmu0950         :::::::::T:--:::::::::::::::::TGR::GEF:DA:T:::EAIATE:QF:DE::
rrnAC0772       ::MSKSL:IST::AEQT:::::::::::::VTEVI:T:V::T:DV:RAVADY:GQSNSV:
HQ1881A         ::MASSI:SHM::STADSESESFSLTDDEI:NS:L:IL:R::::::N:::::::KTNE::
HVO_1446        MGLMAT::V:TADTARAVRT::::::::::::GV::I::S::::::T:::::::T:::::
Hbo0108         ::MATKDE::P::TESDEST:::::::::::TQ:F:VV:RA:::::S::::::I:::ED:
hla0825         :::::::E:DPI-:::::::::::::::::VE::F::V:V:::::::A::::::ESGTD:
NP1592A         ::::::A:A-:--:::::::::::::::::::D:::VVVS:::DV:D::T:::::EA:::
VNG0684         ::::::A:V-:--::::::::::::::::::::VF::::DA:::V:::::DH:ATRD:Q:

consensus       PSGESQLEADVYADELLEERLGALDGVGEYASEEREAVI---DTGGG-----LSVAVDPL
#oth            11.132111.24..1.155134421112211....4324321142411111232.14...
HVO_2131        ::::R:::::T::::::LK::RP::::::::::::PD::::::I:E::::::V:::L:::
Hmu0950         :::::::A::LV:::::::::L::::::S:::::::S:TV:::E:HR:::::-H::::::
rrnAC0772       :T:DD::A::LR::::F:Q:VLGI:::AS::::::AD:K:::T:D:R::::::H::M:::
HQ1881A         :::::PM::::F:::::RN:::S:::I::::::::SSAD::::::S:::::::::CI:::
HVO_1446        ::::T:MA:::F::D::C::I::::::::::::::PESV::::V:T:::::R::::::::
Hbo0108         ::::T:M:::::::D::C::I:DI:::::::::::P:::::::::S:::::::::C::::
hla0825         :::::VMAG:L::::::ADA:T:V::::SFV::::::AV::::A:::VGEDAYA::I:::
NP1592A         ::::R:::::::::::::A::LDV:A::S:::::::S::EA::E::R:::::YH::A:::
VNG0684         A::DT::::::W::D::FD:TESIE::NW::::::D::VTVG:AE:::::::YA::L:::

consensus       DGSSNLKPNNTMGTIFGVYDAPLPATGRDLVAAGYVLYGPTTTMIVARDGTVREYVI-ED
#oth            ...1.121.241..2321.2412.17.5311..1111..121111212215.41222642
HVO_2131        :::T::::::V:::LYSI::E:::TG:EN:L::::I::::V::LVAG:::V:S::IL::S
Hmu0950         ::::::E::SG:::::::::TQP:TI::N:::::F:I:::::S:V:::NDR::::I::H:
rrnAC0772       ::::::E::SG::::::I:SEQP:TV:TN:L:::F:I:::I:S:V:::::S::::IL:::
HQ1881A         :::::::S:AA::::AA::::::::R:S:::::A:::::A:::::A:VE:N:AD:::YQ:
HVO_1446        ::::::::::::::::A:::G::::H::::::::::::::VM::::::N:::D:::LHD:
Hbo0108         :::::::::::::::VA:::::I::::A:ML::A:::::A:::::::::D::T::::Q::
hla0825         ::::::RS::A:::VV::::::::::::::::::::::::I::::::D:DG:::E:VEG:
NP1592A         :::::::S::::::L::::EE::::A:DA:::::::::::I::L:T::::::T:S::D::
VNG0684         :::::V:S::PC::VV:I::Q::::P:SS:::::F:::::::::V::::D::::SLVS:T

consensus       GD----RRVVRDDVTLPDDPTVYGFGGRVPDWTDDFEAYAREVESD--LKLRYGGAMIGD
#oth            1511115342432231.5114111...1133.433.3311333353322......1.11.
HVO_2131        :I::::K:PL:EEL:::G::AIFS:::::NR:F:::::F:::T:RTEGM::::::S::::
Hmu0950         ::::::A:::D:::SV:T:::::::::GREN:N:A:AD::T:LQER::::::::::::A:
rrnAC0772       ::::::K:::D::::V:E::::F::::G:DS:::E::S::EA:RHE:::::::::::VA:
HQ1881A         :S::::YEPIEQE:RV:SE:::::::::::N:PR::NSFVSDI:::TSM::::::::V::
HVO_1446        AS::::HEL::E::S:::EGS:::::::::::::::::F:::::Q:ASR::::::S::::
Hbo0108         :E::::YEA::E:I::::::::::::::::::VES:TE:::DI:::ASM::::::S::::
hla0825         ::GGVS:S::E::LR::E::L:::::::::::P:::T:::::I:DE:::::::::::V::
NP1592A         :T:::::T::T::L:::S::V:::::::::N::PA:AD:VES:A:E::::::::::::::
VNG0684         :A::::TTDL-GP:E::A:::::::::::::::PA::SFV:D::D:::::::::::::A:

consensus       VNQVLTYGGIFAYPALEDAPEGKLRVQFEGYPIGYIIETAGGASSDGEQSLLDVEPDDLH
#oth            11.1.2...2.2..22332.4....32..15.21112.4...22.1.4311.4433342.
HVO_2131        :::I:H:::V:::::QT:::G::::Q::::F:::::::C:::R:::::::::SGT:E:I:
Hmu0950         :S:::::::L:S:::::YR:T::::L::::Q:M:::V:A:::K::::H:::::R:I::I:
rrnAC0772       I::::::::::S:::::SR:::::::::::H:MA::L:S:::R::::D::::EI:::E::
HQ1881A         :::::::::::G::::TN::S:::::::::::::::::C::::::::S::::A::SN:I:
HVO_1446        :::I::::::::::T::S:::::::::::::::::V:::::::T:::TK:::::DK:G::
Hbo0108         :::I::::::::::T:Q:S:::::::::::::V:::::::::R:::::::::A::K:E::
hla0825         ::::::::::::::::V:::D::::LS::AN::A::V:K::::A:N::TDI::::SEGV:
NP1592A         :::::::::V:G::G:::R::::::LL:::H::AA:V:A::::::::DG:::KK::EQ::
VNG0684         :::::V:::V:G::GM:S::D::::A:::AL::A::V::::::::::T::::::A:TR::

consensus       DRTPLYVGNDELIERLEAALA------
#oth            2.2.322.1332123.14233543211
HVO_2131        ::V:V:I:::S:V:S::TR:D::::::
Hmu0950         :::::HL::TS::::::ERYERHE:::
rrnAC0772       E:::::L:::D::D::::NID::::::
HQ1881A         ::::V:::TPS:V::::G:::GKADSE
HVO_1446        A:::M::::T::VAK:::::D::::::
Hbo0108         A:::V::::E::::K::::F:ED::::
hla0825         ::I::::::EA:V::::D:::NE::::
NP1592A         E::::F:::::Y::::::::P::::::
VNG0684         E:::TF::T:DV:AA:D:::PDHTN::