[K] (-) COG1813 Predicted transcription factor, homolog of eukaryotic MBF1 8 genomes BUD0970 8 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG1483 rrnAC0872 HVO_2718 Hbo2447 Hmu1784 - hla1680 NP2072A HQ2874A

Pairwise sequence scores
Consensus score	1273	NP2072A	HQ2874A	hla1680	HVO_2718	Hbo2447	VNG1483	rrnAC0872	Hmu1784
720	NP2072A	1237	617	589	622	628	604	675	678
915	HQ2874A	617	1291	747	756	919	673	641	679
935	hla1680	589	747	1428	860	871	653	634	684
1026	HVO_2718	622	756	860	1302	950	738	734	744
1030	Hbo2447	628	919	871	950	1306	746	647	722
856	VNG1483	604	673	653	738	746	1256	750	784
810	rrnAC0872	675	641	634	734	647	750	1260	860
854	Hmu1784	678	679	684	744	722	784	860	1236

192 symbols
consensus       MAKYSTGGGGGGGDGDSCELCGRSTADLQRANVAGAELLVCPDCAP-HDD-----GKGGS
#oth            .1....133.2243142.....33453.33.1....4.31.43.441.113321646443
NP2072A         ::::::::V::DES:A-:::::AEDRS:ET:T::::::N::DQ:LK::G:::::::DA:Q
HQ2874A         :P:::::S:::S::::::::::Q:::T:TQ:::::::::I:EE:T:::::AG::A:P:S:
hla1680         ::::::::::::D:::A::::::E:T:::::T::::K::::S::R:::::AGNAP:GR:G
HVO_2718        ::::::NR::::::::::::::::::K:R:::::::D:::::::::::GENRHADR:S::
Hbo2447         :P:::::S::::::A:::::::::SPK:R:::::::N:::::::::::::SKH:E:T:::
VNG1483         :P::::::A:S::G:QA:::::STADS::D::::::::T::::::S:::E:::::--SAA
rrnAC0872       :::::::S::DSAG:S-:::::SDGG:::T::::::T:Q::DS::RD:GE::::NERTTG
Hmu1784         :::::::-S:S:SA:E::::::A:D:::ET::::::T:Q::A::SQ::GE::::TS:TE:

consensus       SDASRDDSEG----------------SRKKRAAQNQAKMYDA-AKGDSKHWEEDGTNYED
#oth            334233443511111111111111113.32211234.225.21334.231.123112.15
NP2072A         T:TEDRTQ:R::::::::::::::::K:R:K::::V:RLD:::R:V:TD-:Q-ED:E::E
HQ2874A         NNEE:S:D:P::::::::::::::::::Q:::V:QH:R:H:Q::TS::R:::RE:::::Q
hla1680         :GG::GG:S:GSPGGASSESTGTGTE::::EI:RK::::::S::T::::::::G:::::S
HVO_2718        ::::::G:S:::::::::::::::::N:::::::RT::L::S:::::::::::K:::::K
Hbo2447         :SSDTS:::P::::::::::::::::::::::::R::::::Q::::::::::RE:::::K
VNG1483         A::DG:AADA::::::::::::::::D:TQ::VE:::QQF::VTR:::S::::::::::T
rrnAC0872       N:S:::EQ--::::::::::::::::N::RK::::A::LQ:::QRA:TS:::-::AD:D:
Hmu1784         ::G::G:RDT::::::::::::::::D::R:::::A:::A:::QQP:AS:::-:::::::

consensus       DQLPYLVSDYGEVVAEARQDAGLQIDELAEELDVDEADILAVEQGRATRANVGGSLIRAL
#oth            .2......3..44135...11.1144...4.133124123.1.11..13.1....31321
NP2072A         :P:::::::::TL:EQ:::AE::::::::R:VGA::D:VV:::::::A:::::::::S::
HQ2874A         ::::::::E:::IA:S:::A::FT:::::T::E:ESG:::::::::::::G:::::::E:
hla1680         :R::::::G::DD::A:::::::TVE::::::::::D:LF:::D:::AT:G::::VV:::
HVO_2718        :R::::::G::G::ES::::::::LA:::D:::L::KQL::I:::::::::::::A::::
Hbo2447         :R:::::::::D:::T:::::::TVE:::A:::A::S::D::::::::::G:::::V::I
VNG1483         ::::::::::::R:VR::::::::RS:::A::EI:D::V:::::A:::K::::::V:A::
rrnAC0872       ::::::::K:::R:T:::::E:::TS:::::::L:D::::::::::::Q::::::T:K::
Hmu1784         :::::::::::S::T:::::::::TQ::::::S:::S:V:::::::::Q:G::::VVAK:

consensus       EERLDVTLVDE-
#oth            .34.11312141
NP2072A         :::::IE:A:T:
HQ2874A         :ST::I::::::
hla1680         ::::G:DI::::
HVO_2718        ::::::::::::
Hbo2447         ::K:::::::::
VNG1483         :DF:::Q:S:D:
rrnAC0872       :QY::ID::ESN
Hmu1784         :DF:::E:AE-: