[S] (-) COG2138 Uncharacterized conserved protein 8 genomes BUD0982 8 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG1561 rrnAC3011 HVO_B0054 Hbo1619 Hmu1999 - hla2072 NP1108A HQ3032A

Pairwise sequence scores
Consensus score	3067	HVO_B0054	Hbo1619	NP1108A	HQ3032A	VNG1561	rrnAC3011	Hmu1999	hla2072
2469	HVO_B0054	3091	2731	2171	2125	1077	2247	2214	2271
2434	Hbo1619	2731	3092	2119	2159	1086	2227	2206	2253
2387	NP1108A	2171	2119	2987	2061	1058	2186	2230	2205
2510	HQ3032A	2125	2159	2061	3156	1154	2412	2393	2379
1299	VNG1561	1077	1086	1058	1154	1567	1220	1198	1259
2698	rrnAC3011	2247	2227	2186	2412	1220	3082	2573	2577
2704	Hmu1999	2214	2206	2230	2393	1198	2573	3092	2666
2782	hla2072	2271	2253	2205	2379	1259	2577	2666	3116

420 symbols
consensus       --------------A-ATPPSLDDEAVLLVGHGSRREKSNEQVRTLAADLEGRLGVPVDA
#oth            111111111133344644445212212213111111221111123113521521331221
HVO_B0054       ::::::::::::MSLERPD:A:::D::::::::::::E::::::::::K::S::S:::::
Hbo1619         ::::::::::::::MRTEQ:::::D:I::::::::::::::::::::GK::TE:S:::::
NP1108A         ::::::::::::::-:----M::A:::V:A::::::::::::::::::G::::::F::T:
HQ3032A         MSNQNIKTSISPSPQS::AARF:::::::I::::::K::::::E:::::::A::D::T::
VNG1561         ::::::::::::::-:--------------------------------------------
rrnAC3011       :::::::::::MSE:ITA:ET:::::::::::::::::::::::D::VE::::::I::::
Hmu1999         ::::::::::MTAD:A:::V::::::::::::::::::::::::E:::AV:E:::::T::
hla2072         ::::::::::VTAD:TS::V::::::::::::::::::::::::E:::::::::::::::

consensus       AFLELAEPSIEDAIEGLAASVSRVTVVPLSLFAASHVKNDVPLAVQQARTAHDDLTIHNG
#oth            222111213143114331332254222311111111112111222341155232333321
HVO_B0054       :YI:::::::D::::TM:PTCRTM::::::::::::::::::::::R::AT:::TEFRF:
Hbo1619         :YI::::::::::::T::PTCRTL::I:::::::::::::::M:::T:::KY::V:F:F:
NP1108A         G:I:::::::PE:::SV:P:::D:::I:::::::::::A::::V:NE:::E:T:VNV:::
HQ3032A         ::::::T:A::E::DT::::::AIS::H::::::::::::::::LE::::DYPE:::N::
VNG1561         ------------------------------------------------------------
rrnAC3011       ::::::::A:DE::A:::RA::Q:S::H:::::::::::::::::E:::E::PE:::N::
Hmu1999         G::::::::::A::A::::::::::::Q:::::::::::::::::E:::S::P:::::::
hla2072         G:::::::D:A:::G::::::::::L:Q:::::::::::::::::::::D::::::V:::

consensus       AHLGVHPALVDLLDDRAAAVEAELGVDREDDDVAVVLCARGSSDPDSNGDVHKLARLLYE
#oth            311121122321112122211331321145112321211111111121312111211111
HVO_B0054       S:::I::S::::::E::R:::SD:::::::::::::::::::::::::::::::::::::
Hbo1619         S:::I::SI:::::::IRT::SD:::::DN::::::::::::::::::::::::S:::::
NP1108A         R:::::::I:E:::::::::::::N::::::::V::::::::::::::::::::::::::
HQ3032A         :::::::::I:::::::::::ST:E:::HT::::::::::::::::::::::::::::::
VNG1561         ------------------------------------------------------------
rrnAC3011       :::::::::L:::::::::::::::::::E::::A:V:::::::::A:A:::::::::::
Hmu1999         ::::::::I::::::::::::::::L::TA::LT::::::::::::A:S:A:::::::::
hla2072         :::::::::::::::::R:::T::::::D:::::::::::::::::A:S:A:::::::::

consensus       GREFARVEAAFIGVTEPLLEDTLHTVAKRRPDAVVVLPYMLGDGVLTGRIRDGADEFDEE
#oth            112143134312111413123211521141112211311........2..312133.121
HVO_B0054       ::::T:::S::::::T:R::E:::::::D::::::::::::::::::E::V:T:ET::::
Hbo1619         ::::T:::PS:::::S:R::::::S:::D:::::::V::::::::::Q::I:T:ET::D:
NP1108A         ::A::D::::::::::::::PA:::::::::::::::::::::::::E:::ETTAT::D:
HQ3032A         ::::DD:A:T:::::D:V:DE:::R:::T::::I:::::::::::::::::E:::S::::
VNG1561         ---------------------------------------::::::::::::E::A:::AD
rrnAC3011       ::::S::::S:::::::::D::::DI::T:::::::I:::::::::::::K:::R:::::
Hmu1999         ::A:DH::TS::::::::::::::::::::::G::::::::::::::Q::::R::A::::
hla2072         :::::::DT::V:::::::::A::G:::S::::::::::::::::::::::::::::HA:

consensus       YPYVDAAAGDPLGTDSRLLDVLGDRWQEARTGSVEMSCDTCKYKVELDGYEEDVGGARAM
#oth            .1.23.1212.....5.2121.2..31...111.2..........1.3.11313...1.1
HVO_B0054       ::::::G:SG:::::A:VVET:A::Y::::S::::::::::::::::A:::D:E::::::
Hbo1619         ::::R:G:SG:::::E::V:::A::C::::S::::::::::::::::S:::D:Q::::::
NP1108A         :R:AE::C:::::::D:::T::A::FE:::::D:S::::::::::::::F:GEA::::::
HQ3032A         :::LS:::::::::::::::::S::::::::D:::::::::::::D:E::A::::::::T
VNG1561         ::::E::C:::::::::::::::::::::::::::::::::::::::::::::::::K::
rrnAC3011       :::::::P:E:::::T:::::::::::::::::::::::::::::::::::::Q::::::
Hmu1999         :::::::::::::::::::::::::::::::D::::::::::::::::::::::::::::
hla2072         :::::::::::::::P:I:::::::::::::D::D::::::::::::::::A::::::::

consensus       LRALTHQAEHADRDDVDDDPHVHDAPEKHVAVCTNQTCAADGAAAVLERLRQAARDSDAC
#oth            ..113..12.1..211121.12....21..1..1.1...23.112...2...42..2242
HVO_B0054       ::S:V::::::::S::::::::::::::::::::::::::S:::T:::Q:::GV::A:D:
Hbo1619         ::S:V::::::::S::::::::::::A:::::::::::::S:::T:::Q:::H:::::D:
NP1108A         :::M::::A::::S:I:EE:::::::D:::T::::R:::DA:::T::::::::V::R-GI
HQ3032A         ::::I::ET::::::::S::DT::::A:::T::M::::::::::S:::Q:::S:::::::
VNG1561         ::::N::EA:E:::::A::::A::::DR::::::::::::E::P::::::::E:::A:ED
rrnAC3011       :::::::::::::EN::::::::::::::::::::::::Q:::P::::::::::::::Q:
Hmu1999         :::::::ET::::EN:::E::A::::::::::::::::::::S::::::::::E:::E::
hla2072         :::::::ET::::::::::::::::::::::::::::::::::P::::G::::::::EE:

consensus       DARITRSSCLGRCGDGPMVAVYPDGVWYGGVDPDDADRIVSSHLDRDRIVSDLVDQTL--
#oth            12121.1...11..1..2......21..13.4311241.1..111......2112.2.11
HVO_B0054       :VHVS::::::Q:::::I::::::S::::::T:::T::::::::E::::::N::H:S:::
Hbo1619         :VHFS::::::Q:::::I::::::SI:::S:T:::TE:::::::E:::::::::H:S:::
NP1108A         ::::::::::D::::::N::::::N::::::A:E:V:::A::-:E::::::E::::::::
HQ3032A         :V:::::::::::::::::::::::::::S::DEG:TE::::::::::::::Y:::::::
VNG1561         SL:V::T::::Q:::::N::::::::::QR::::::G::::::T:::::::::DS:L:::
rrnAC3011       ::::::::::::::E::::::::::::::::EDE::AE:::::::::::::E::::::::
Hmu1999         :::V::::::::::E::::::::::::::::GE:::E::::::::::::::E::::::SQ
hla2072         :::::::::::::::::::::::::::::D::G:::::::::::::::::::::::::::