[R] (-) COG2945 Predicted hydrolase of the alpha/beta superfamily 8 genomes BUD0997 8 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG1833 rrnAC3468 HVO_2635 Hbo2207 Hmu2480 - hla1252 NP1966A HQ3030A

Pairwise sequence scores
Consensus score	1503	HQ3030A	NP1966A	rrnAC3468	Hmu2480	VNG1833	hla1252	HVO_2635	Hbo2207
712	HQ3030A	1683	619	569	471	475	549	605	579
906	NP1966A	619	1553	797	665	729	673	708	715
992	rrnAC3468	569	797	1522	723	767	794	800	764
799	Hmu2480	471	665	723	1280	548	505	611	566
960	VNG1833	475	729	767	548	1586	814	831	839
1021	hla1252	549	673	794	505	814	1654	938	860
1173	HVO_2635	605	708	800	611	831	938	1673	1124
1096	Hbo2207	579	715	764	566	839	860	1124	1597

237 symbols
consensus       -MSETVLIPGGRDVRATLDAA-------------------DADAVVVACPPHPQHGGHRG
#oth            13442243223113323115343334322323331111116524222111111132.212
HQ3030A         :::H::HFN::::A:GH::TRESKAKY:::::::::::::TI:SC:I:::::::::::SS
NP1966A         :::KS:VV:AD::I:G::::P::::::::::::::::::::::RC::::::::::::N:N
rrnAC3468       :-MT::G:::::::T:S::RP:::::::::::::::::::AS:T:I::::::::Y::S:S
Hmu2480         :--------------------:::::::::::::::::::--------------M::S:S
VNG1833         MHQ::::V::A:::E::::EPADG::::::::::::::::::T:C::::::::::R::::
hla1252         :V:::::::::::::::::T:ASDGGGDATGNGS::::::R:::::::::::::QR::::
HVO_2635        ::T::I:V:::::::::::P:RGDGIDDADETDDTDDAAAGR::::I:::::::QQ::::
Hbo2207         :VT::::::::::::G:::::DDGINDCSEGDKT::::::ST:T::I::::::::R::::

consensus       DRRLVAVSDALTDRGIDCLRFDYGAWDEGRGERADALNALEWARERYDRVGLFGFSFGGA
#oth            .5..6..133.652232...11..3..2.3..33.342133..611124211..1...14
HQ3030A         ::::C::::Q:PP-E:::::IT::S::H:H::Y::VA::::::HN:::QC::::Y:::A:
NP1966A         :P::E::::D:---DAA:::::::P:::::::LE:VRA:YA:::::::A:::::Y::::C
rrnAC3468       :S::K::::::AP-D:S:::::::::::::::::::E:::A::D::::A:::::Y:::A:
Hmu2480         ::::R::::::G:::VA:::::::P::::::::R:C:A::::::::F:S:A:::Y:::AG
VNG1833         :D::Q::AA::VED:LA:::::::D::G:M:::E::R::IR::G:::AHTAV:::::::S
hla1252         :E::T:::N:::::::::::::::D::::Y::ST::D:TVG::V:::E:::::::::::T
HVO_2635        :A::::::::::A::V:::::::::::::Y:::::::R:V:::A::::::::::::::::
Hbo2207         :D::::::EE:NR::::::::::::::::Y:::::T:R:V:::S:Q::::A:::::::::

consensus       VALLAAAE-GA---DPAAVSALAPAARLADG--LDAVAALDD---IDVPVQVVYGTRDDT
#oth            3.232.231542244342222.2.234232221212321254111333.32241111.43
HQ3030A         L:IGV:TT:ST:::CVEF::::::PQSID::SVVETTT::YN:::TNI:T:LI:::Q:EM
NP1966A         L::V:::AESEAGTP:S::AV:S:::S::A:E:::::::VA::::::A:MAL:::E::TM
rrnAC3468       :::CT::A:HDTAA::::L:V:::P:GVTAH:::::A::::A:::::C:::::VAE::A:
Hmu2480         :::::::::AD::PQ:::::V:::P:::D::::TETPP:VG::::::C:L::C::E::::
VNG1833         I:A::::T:TE::H:LW:A:L:::T:E::A::::::A:::T::::VPA::::A:A:::T:
hla1252         :::VT::S:RP:::GL:G:C::::T:::NPD::V::::V:::LIDLS::TRIL:A:::S:
HVO_2635        M::::::::::::::VG:::::G::G::::D::::::::F:R::::P::::::::::::I
Hbo2207         M:::::V::::::::A:::::::::HK:::D::::V:::FPE::::P::::::::::::V

consensus       ADWEPVVERAR-EAGQT---VASLPADHFFVGQHGRVGAAVGAF----LVSHL--S-
#oth            212421122132253541112441321.2.1136331233134.1112364515433
HQ3030A         ISIN:T::MLQQN:SSDKFDIR:F:TG:A:QMFLDK::I::SS:ADNITN:ERKY:A
NP1966A         I:ATA:ADALT:D::GD::::::::::::::::TQ:::::IA:::::FNDGA:PD:V
rrnAC3468       V::::::D::T::L:::::::ER:::::H::::S::I:ET::P::::::RD::::-:
Hmu2480         V::R:::AA:::DR:A::::IE::::::H::::GE::SVCITS:::::NEI::::-:
VNG1833         ::::::::A::SDPET::::::E:D:::::::K::T:A:T::E:::::::G:RRGR:
hla1252         ::::::::::K::L:IE:::TIGFES::::::RA:D::EE::::::::FGPR:ED:L
HVO_2635        :::K:::::::::YH:P::::VEFA::::::::EDK:A:::AD::::::::N:GVE:
Hbo2207         ::A:R:AA:::::FE:S::::VA:E::::::::::K:AET:SD::::::T:W:::-: