[I] (Sbm) COG2185 Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding) 8 genomes BUD1007 8 proteins a Hsa Halobacterium sp. NRC-1 b Hma Haloarcula marismortui f Hvo Haloferax volcanii g Hbo Halogeometricum borinquense h Hmu Halomicrobium mukohataei i Hut Halorhabdus utahensis j Hla Halorubrum lacusprofundi q Nph Natronomonas pharaonis x Hwa Haloquadratum walsbyi VNG0673 rrnAC0934 HVO_0830 Hbo0704 Hmu1056 - hla0029 NP2710A HQ2301A

Pairwise sequence scores
Consensus score	1034	HQ2301A	VNG0673	rrnAC0934	Hmu1056	HVO_0830	NP2710A	Hbo0704	hla0029
818	HQ2301A	1025	766	751	793	798	805	819	772
881	VNG0673	766	1028	776	770	819	812	850	823
881	rrnAC0934	751	776	1175	845	790	855	858	830
882	Hmu1056	793	770	845	1064	803	830	868	837
884	HVO_0830	798	819	790	803	1046	818	871	791
924	NP2710A	805	812	855	830	818	1069	873	828
966	Hbo0704	819	850	858	868	871	873	1075	912
906	hla0029	772	823	830	837	791	828	912	1028

160 symbols
consensus       ----------------MSAD----QEQRTIRCLVAKVGLDGHDRGAHVIARAFRDAGFEV
#oth            1111111111111221..312211543141..11..............12..1.......
HQ2301A         ::::::::::::::::::TE::::NK:QSV::MI::::::::::::::V:::::::::::
VNG0673         ::::::::::::::::::E:::::-ST:NV:::::::::::::::::::T::::::::::
rrnAC0934       MMDRARMKTHRAVRTG::VEQE:::TE:::::::::::::::::::::::::L:::::::
Hmu1056         ::::::::::::::::::::QQ::T:GQR::::::::::::::::::::S::::::::::
HVO_0830        ::::::::::::::::::::::::S::::::::I:::::::::::::::S::::::::::
NP2710A         :::::::::::::MWG::TE::::G:::::::::::::::::::::::::::::::::::
Hbo0704         ::::::::::::::::::::TERG:Q:::::::I::::::::::::::::::::::::::
hla0029         :::::::::::::::::::E::::::T:AV::::::::::::::::::::::::::::::

consensus       IYSGLHRAPDEIVQAAVQEDVDVLGISILSGAHNTLVPKIIDGLKEYDAFEDTLVIVGGI
#oth            1.....21.1.11..1.......1.........2....1123..31.1.3211.112..1
HQ2301A         ::::::K::E:::::::::::::::::::::::K::::::MN::E::G:KSE:::LA::V
VNG0673         ::::::K::::::::::::::::::::::::::::::::::E::A::::A::::::::::
rrnAC0934       :::::::::::V:::::::::::V::::::::::::::::L:::R:::::D:R:IL::::
Hmu1056         :::::::::E:V::::::::::::::::::::::::::Q:L::::::G::::::::::::
HVO_0830        ::::::::::::I::T:::::::::::::::::::::::VMA::E::G:LD:::::::::
NP2710A         ::::::NS:::::::::::::::::::::::::D::::::L:::::::::::::::T:::
Hbo0704         :::::::::E::::::::::::::::::::::::::::::::::::::::::::IL::::
hla0029         V::::::::E:::::::::::::::::::::::::::::V:E:::K::::::::IL::::

consensus       IPDEDRAELRDAGVDEIFGPGTPMEETIEFIRENAPER--
#oth            1.11.442.435.1211....11131113113211.3.41
HQ2301A         ::E:::DD:::H:IAA::::::SID::V::::::::Q:::
VNG0673         :::::::D:EA::::A::::::::AD::S::ES:::H:D:
rrnAC0934       V::D:QE:::GQ:::::::::AS:::M:DY:H::::::::
Hmu1056         V::D:K:::::L::A::::::AS:D:M::YV::H::D:ER
HVO_0830        ::E:::PG:LEE:::A::::::::Q:::D:VK:H::::P:
NP2710A         :::::HD::Y:::::::::::AS:::::T:V:::::::::
Hbo0704         V:::::P::KEM::S:V:::::::Q:::::V:::::Q:D:
hla0029         :::D:ET::KAL::A:V:::::::::::::::N:L:::A: